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41.
Sebastien Fantini Jason Clohessy Karine Gorgy Florence Fusalba Christoffer Johans Ky?sti Kontturi Vincent J Cunnane 《European journal of pharmaceutical sciences》2003,18(3-4):251-257
The transfer of ionic species of three beta-blockers (propranolol, sotalol and timolol) has been studied by cyclic voltammetry at a macroscopic water 1,2-dichloroethane (1,2-DCE) interface. The aqueous solution has been gellified in order to study the effect of the gel on the transport properties of the drugs. The gelling agent also stabilizes the interface overcoming mechanical instability. The standard potential and standard Gibbs energy of transfer across the interface, the partition coefficient and the diffusion coefficient of each drug were determined in the presence of a gelled interface. The diffusion coefficients were shifted relative to those obtained at normal water 1,2-DCE interfaces (free of gel). 相似文献
42.
Jamir D. Arlikar Shivaji B. Mane Nitin P. Dhende Yogendra Sanghavi Arvind G. Valand Pradip R. Butale 《Pediatric surgery international》2009,25(3):289-292
Fetus in fetu is a rare disorder. Its embryopathogensis and differentiation from teratoma has not been well established. It
is a parasitic twin of a diamniotic monozygotic twin. Here we report, two cases of fetus in fetu with review of literature.
In case report 1, a 2-year-old boy was referred for asymptomatic lump in abdomen since birth. X-ray showed the mass in the
abdomen with some calcification and fluid inside. CT scan reported a heterogenous mass in the retroperitoneum with bony malformation.
CT showed presence of three vertebrae in it. After surgically excising the mass and opening the sac it showed presence of
trunk and two limbs with one of the limbs having a nail. Histopathology showed presence of GI tract. In case report 2, 4 month
female was found to have lump in the abdomen by housemaid while bathing. X-ray showed a soft tissue shadow while ultrasonography
revealed cystic mass arising from right kidney. CT suggested cystic mass with calcification not arising from kidney. During
exploration whole mass was excised and there was frank fetus inside it. Histopathology confirmed presence of four vertebral
bodies with germ layers. Although fetus in fetu is rare condition, correct diagnosis using imaging can be made before surgery.
Complete excision is curative. 相似文献
43.
Jamir Sardá Jr. Michael K. Nicholas Ali Asghari Cibele A.M. Pimenta 《European Journal of Pain》2009,13(2):189-195
There is evidence that cognitions (beliefs) and mood contribute to physical disability and work status in people with chronic pain. However, most of the current evidence comes from North America and Europe. This study examined the contribution of demographic, pain and psychosocial factors to disability and work status in chronic pain patients in two matched samples from quite different countries (Australia and Brazil). Data were collected from 311 chronic pain patients in each country. The results suggest that although demographic and pain variables (especially pain levels) contribute to disability, self‐efficacy beliefs made a significant contribution to disability in both samples. Age and educational level also contributed to unemployment in both samples. But there were some differences, with self‐efficacy and physical disability contributing to work status only in the Brazilian sample. In contrast, depression was the only psychological risk factor for unemployment in the Australian sample. Catastrophising and pain acceptance did not contribute to disability or unemployment in either sample. These findings confirm key aspects of biopsychosocial models of pain in two culturally and linguistically different chronic pain samples from different countries. They suggest that different chronic pain populations may share more similarities than differences. 相似文献
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