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181.
Anette Kersting Kristin Kroker Johannes Steinhard Isabell Hoernig-Franz Ute Wesselmann Katharina Luedorff Patricia Ohrmann Volker Arolt Thomas Suslow 《Archives of women's mental health》2009,12(4):193-201
The objective of this study was to compare psychiatric morbidity and the course of posttraumatic stress, depression, and anxiety
in two groups with severe complications during pregnancy, women after termination of late pregnancy (TOP) due to fetal anomalies
and women after preterm birth (PRE). As control group women after the delivery of a healthy child were assessed. A consecutive
sample of women who experienced a) termination of late pregnancy in the 2nd or 3rd-trimester (N = 62), or b) preterm birth (N = 43), or c) birth of a healthy child (N = 65) was investigated 14 days (T1), 6 months (T2), and 14 months (T3) after the event. At T1, 22.4% of the women after TOP
were diagnosed with a psychiatric disorder compared to 18.5% women after PRE, and 6.2% in the control group. The corresponding
values at T3 were 16.7%, 7.1%, and 0%. Shortly after the event, a broad spectrum of diagnoses was found; however, 14 months
later only affective and anxiety disorders were diagnosed. Posttraumatic stress and clinician-rated depressive symptoms were
highest in women after TOP. The short-term emotional reactions to TOP in late pregnancy due to fetal anomaly appear to be
more intense than those to preterm birth. Both events can lead to severe psychiatric morbidity with a lasting psychological
impact. 相似文献
182.
Zusammenfassung Die zunehmende Verbreitung von Cannabiserfahrung in der Bev?lkerung hat für die Psychiatrie erhebliche Auswirkungen. Die ?sterreichische
Gesellschaft für Psychiatrie und Psychotherapie hat deshalb ein state of art-paper verfasst, in welchem der heutige Wissensstand
über die akuten und chronischen Cannabiswirkungen zusammengefasst wird. Von psychiatrischer Relevanz sind insbesondere die
Fragen, ob Cannabis Sensibilisierungsdroge sei, ob es sogenannte Amotivationssyndrome ausl?sen k?nne und welcher Zusammenhang
zwischen Cannabiskonsum und Psychose besteht. Besonders diskutiert werden Indikationen und Verwendung von Cannabis und Cannabinoiden
als Medikament. Abschlie?end werden eine Reihe von Empfehlungen für die rechtlichen Fragen und justizielle Reaktionen bei
Cannabismissbrauch gegeben.
相似文献
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184.
Christian Güldner Julia Heinrichs Rainer Wei? Annette Paula Zimmermann Benjamin Dassinger Siegfried Bien Jochen Alfred Werner Isabell Diogo 《European journal of medical research》2013,18(1):30
Background
With the Bonebridge, a new bone-anchored hearing aid has been available since March 2012. The objective of the study was to analyse the visualisation of the implant itself as well as its impact on the representation of the bony structures of the petrosal bone in CT, MRI and cone beam CT (CBCT).Methods
The Bonebridge was implanted unilaterally in two completely prepared human heads. The radiological imaging by means of CBCT, 64-slice CT, 1.5-T and 3.0-T MRI was conducted both preoperatively and postoperatively. The images were subsequently evaluated from both the ENT medical and nd radiological perspectives.Results
As anticipated, no visualisation of the implant or of the petrosal bones could be realised on MRI because of the interactive technology and the magnet artefact. In contrast, an excellent evaluability of the implant itself as well as of the surrounding neurovascular structures (sinus sigmoideus, skull base, middle ear, inner ear, inner auditory canal) was exhibited in both the CT and in the CBCT.Conclusion
The Bonebridge can be excellently imaged with the radiological imaging technologies of CT and CBCT. In the process, CBCT shows discrete advantages in comparison with CT. No relevant restrictions in image quality in the evaluation of the bony structures of the petrosal bones could be seen. 相似文献185.
Tropism of the in situ growth from biopsies of childhood neuroectodermal tumors following transplantation into experimental teratoma
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Seema Jamil Isabell Hultman Jessica Cedervall Rouknuddin Q. Ali Gabriel Fuchs Bengt Gustavsson Jurate Asmundsson Bengt Sandstedt Per Kogner Lars Ährlund‐Richter 《International journal of cancer. Journal international du cancer》2014,134(7):1630-1637
Experimental teratoma induced from human pluripotent stem cells with normal karyotype can be described as a failed embryonic process and includes besides advanced organoid development also large elements of tissue with a prolonged occurrence of immature neural components. Such immature components, although benign, exhibit strong morphological resemblance with tumors of embryonic neuroectodermal origin. Here, we demonstrate that biopsy material from childhood tumors of neural embryonic origin transplanted to mature experimental teratoma can show an exclusive preference for matching tissue. Tumor specimens from five children with; Supratentorial primitive neuroectodermal tumor (sPNET); Pilocytic astrocytoma of the brainstem; Classic medulloblastoma; peripheral primitive neuroectodermal tumor (pPNET) or neuroblastoma (NB), respectively, were transplanted. Analysis of up to 120 sections of each tumor revealed an engraftment for three of the transplanted tumors: pPNET, sPNET, and NB, with a protruding growth from the latter two that were selected for detailed examination. The histology revealed a strict tropism with a non‐random integration into what morphologically appeared as matched embryonic microenvironment recuperating the patient tumor histology. The findings suggest specific advantages over xenotransplantation and lead us to propose that transplantation to the human embryonic microenvironment in experimental teratoma can be a well‐needed complement for preclinical in vivo studies of childhood neuroectodermal tumors. 相似文献
186.
Waltering Isabell Schwalbe Oliver Hempel Georg 《International journal of clinical pharmacy》2022,44(1):79-89
International Journal of Clinical Pharmacy - Background Pharmacists in community pharmacies worldwide successfully conduct an increasing number of medication reviews (MR). Since June 2012 MR are... 相似文献
187.
Benita Brünner Juliane Saumweber Merve Samur Denise Weber Isabell Schumann Deepthi Mahishi 《Journal of neurogenetics》2020,34(1):123-132
AbstractIn many animals, the establishment and expression of food-related memory is limited by the presence of food and promoted by its absence, implying that this behavior is driven by motivation. In the past, this has already been demonstrated in various insects including honeybees and adult Drosophila. For Drosophila larvae, which are characterized by an immense growth and the resulting need for constant food intake, however, knowledge is rather limited. Accordingly, we have analyzed whether starvation modulates larval memory formation or expression after appetitive classical olfactory conditioning, in which an odor is associated with a sugar reward. We show that odor-sugar memory of starved larvae lasts longer than in fed larvae, although the initial performance is comparable. 80 minutes after odor fructose conditioning, only starved but not fed larvae show a reliable odor-fructose memory. This is likely due to a specific increase in the stability of anesthesia-resistant memory (ARM). Furthermore, we observe that starved larvae, in contrast to fed ones, prefer sugars that offer a nutritional benefit in addition to their sweetness. Taken together our work shows that Drosophila larvae adjust the expression of learned and naïve choice behaviors in the absence of food. These effects are only short-lasting probably due to their lifestyle and their higher internal motivation to feed. In the future, the extensive use of established genetic tools will allow us to identify development-specific differences arising at the neuronal and molecular level. 相似文献
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189.