全文获取类型
收费全文 | 11253篇 |
免费 | 734篇 |
国内免费 | 62篇 |
专业分类
耳鼻咽喉 | 102篇 |
儿科学 | 309篇 |
妇产科学 | 228篇 |
基础医学 | 1634篇 |
口腔科学 | 255篇 |
临床医学 | 990篇 |
内科学 | 2565篇 |
皮肤病学 | 424篇 |
神经病学 | 1131篇 |
特种医学 | 262篇 |
外科学 | 929篇 |
综合类 | 57篇 |
现状与发展 | 1篇 |
一般理论 | 3篇 |
预防医学 | 1346篇 |
眼科学 | 217篇 |
药学 | 780篇 |
中国医学 | 50篇 |
肿瘤学 | 766篇 |
出版年
2024年 | 6篇 |
2023年 | 132篇 |
2022年 | 262篇 |
2021年 | 506篇 |
2020年 | 260篇 |
2019年 | 430篇 |
2018年 | 519篇 |
2017年 | 315篇 |
2016年 | 302篇 |
2015年 | 375篇 |
2014年 | 525篇 |
2013年 | 639篇 |
2012年 | 982篇 |
2011年 | 945篇 |
2010年 | 549篇 |
2009年 | 445篇 |
2008年 | 714篇 |
2007年 | 705篇 |
2006年 | 601篇 |
2005年 | 639篇 |
2004年 | 546篇 |
2003年 | 504篇 |
2002年 | 453篇 |
2001年 | 68篇 |
2000年 | 28篇 |
1999年 | 74篇 |
1998年 | 74篇 |
1997年 | 60篇 |
1996年 | 56篇 |
1995年 | 49篇 |
1994年 | 27篇 |
1993年 | 38篇 |
1992年 | 26篇 |
1991年 | 22篇 |
1990年 | 14篇 |
1989年 | 7篇 |
1988年 | 12篇 |
1987年 | 8篇 |
1986年 | 7篇 |
1985年 | 7篇 |
1984年 | 14篇 |
1983年 | 13篇 |
1982年 | 7篇 |
1981年 | 8篇 |
1980年 | 7篇 |
1979年 | 6篇 |
1978年 | 7篇 |
1977年 | 6篇 |
1974年 | 5篇 |
1968年 | 4篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
22.
23.
24.
Thilo Klindert Isabel Stroetmann Gunther Seitz Georg Hfner Klaus Th. Wanner Gerlinde Frenzen Brigitta Eckhoff 《Archiv der Pharmazie》1997,330(6):163-168
A number of novel pyridazinomorphinans have been synthesized by the inverse electron demand Diels-Alder reaction of various 3,6-disubstituted 1,2,4,5-tetrazines with enamines derived from dihydrocodeinone and with codeinone. Reduction of some of the pyridazinomorphinans did not furnish the expected pyrroloepoxymorphinans; in all cases investigated reductive cleavage of the epoxybridge was observed to yield dihydropyridazino- or pyrrolomorphinans. The structures of all new compounds were assigned by the spectral data, that of the cycloadduct of codeinone was additionally verified by X-ray crystallography. Compounds 5a, 8, 11a , and 16 have been evaluated for their affinity at μ and κ opioid receptors in radioligand binding assays. Their ability to inhibit [3H]DAMGO binding at μ and [3H]U 69.593 binding at κ receptors, respectively as compared to codeine has been found to be lower. 相似文献
25.
António Travassos Susana Teixeira Pinto Ferreira Isaura Regadas Ana Sofia Travassos Florindo Esteves Esperancinha Isabel Prieto Grapa Pires Robert van Velze A Valido Maria do Céu Machado 《Ophthalmic surgery, lasers & imaging》2007,38(3):233-237
The anatomic response to intravitreal bevacizumab injection in three patients with aggressive, posterior retinopathy of prematurity is described. In all cases, the worse eye was treated with a single intravitreal injection of 0.75 mg of bevacizumab as monotherapy or complementary to laser therapy. In 24 hours, all injected eyes showed regression of the tunica vasculosa lentis and iris vessel engorgement and disappearance of iris rigidity. In addition, plus disease and retinal proliferation began to regress. None of the eyes required additional treatment. Follow-up of up to 10 months 相似文献
26.
The smoking control policies recommended by the World Health Organisation have achieved a slight decrease in smoking prevalence in developed countries, although associated mortality is still very high. The use of tobacco products other than cigarettes and even medicinal nicotine (known as nicotine replacement therapy [NRT]) has been proposed as a risk reduction strategy. Among the tobacco products with less individual risk than cigarettes would be any type of tobacco without smoke (smokeless) with a low content in nitrosamines and modified cigarettes; both forms included under the PREP (Potentially Reduced Exposure Products) concept. The idea would be to promote these products among patients who cannot quit smoking or wish to reduce their risk without giving up nicotine intake. The possible effects of risk reduction strategies, including PREP, on the decreased prevalence and morbidity and mortality are reviewed, and the possible implications that this measure could have in Spain are analysed. Tobacco control measures in Spain have only been made recently and are still insufficient. Therefore, the current priority in Spain is to develop control policies that have proven to be more than effective. The marketing and advertising of new tobacco products, even with reduced potential risk, seems more a serious threat than an opportunity for developing smoking control policies. 相似文献
27.
Mario Sénéchal Isabelle Lemieux Isabel Beucler Gerard Drobinski Sylvie Cormont Michelle Dubois Iradj Gandjbakhch Jean-Pierre Després Richard Dorent 《The Journal of heart and lung transplantation》2005,24(7):819-826
BACKGROUND: This study evaluated the prevalence of the atherogenic metabolic triad and the hypothesis that waist circumference and fasting triglyceride concentrations could be used as screening tools for identification of the atherogenic metabolic triad in a population of heart transplant men. It also evaluated the relationship between the atherogenic metabolic triad and coronary artery disease (CAD). METHODS: In the study group of 83 consecutive male heart transplant patients having their routine annual coronarography, 23 patients (28%) were characterized by the atherogenic metabolic triad defined by the presence of elevated fasting insulin and apolipoprotein B concentrations and by small low-density lipoprotein (LDL) particles. RESULTS: Seventy-seven per cent of patients with waist circumference values >/= 90 cm and with elevated triglyceride levels (>/=2.0 mmol/liter) were characterized by this atherogenic metabolic triad. Patients with the atherogenic metabolic triad were at markedly increased risk of CAD (odds ratio of 25.3, 95% CI: 1.11-577.3, p < 0.04) compared to heart transplant patients without the atherogenic metabolic triad. CONCLUSIONS: About 30% of heart transplant patients showed the features of the atherogenic metabolic triad. Measurement and interpretation of waist circumference and fasting triglycerides could be used among heart transplant patients to early identify men characterized by the presence of elevated fasting insulin and apolipoprotein B concentrations and small LDL particles. The presence of the atherogenic metabolic triad identified patients at high risk of CAD even in the heart transplant population. 相似文献
28.
Luís Mariano Isabel Vila?a Jorge Almeida Mota Garcia Maria Júlia Maciel 《Revista portuguesa de cardiologia》2007,26(3):265-270
Apical ballooning is a novel clinical entity reported in different contexts of physical and psychological stress, which is more common in middle-aged women. Of unknown etiology, the syndrome is characterized by a sudden and transient dilatation of the left ventricular apex in the absence of obstructive atherosclerotic coronary disease or evidence of myocardial necrosis, with total late recovery of ventricular function. The authors report the case of a 53-year-old woman who was admitted to the emergency room with left arm ischemia and low cardiac output, requiring ventilatory support. Left catheterization showed typical medial and apical myocardial dysfunction, with normal coronary arteries. Transesophageal echocardiography revealed a thrombus attached to the lower face of the aortic arch, which probably explained the thromboembolism of the arm but was unlikely to be the cause of the left ventricular dysfunction since there were no enzymatic or electrocardiographic signs of myocardial necrosis and normal wall motion was fully recovered. 相似文献
29.
30.
Ana Berta Sousa Ana Medeira Binita M Kamath Nancy B Spinner Isabel Cordeiro 《Revista portuguesa de cardiologia》2006,25(4):447-452
Although most congenital heart defects are isolated abnormalities of embryonic development, with little genetic contribution, a small number are components of syndromes. In such cases, an accurate diagnosis has important implications for individual prognosis and familial genetic counseling. Alagille syndrome (AGS) is a dominantly inherited multisystem developmental disorder, which primarily affects the liver, heart, eyes, skeleton, and face. In recent years, the identification of the AGS gene has drawn attention to the existence of subclinical carriers, and broadened the spectrum of phenotypical variation associated with this syndrome. The authors present a case of mother and son with benign stenosis of the pulmonary artery branches. Subtle facial aspects suggested the diagnosis of AGS, which was confirmed by molecular analysis. Relevant clinical investigations and diagnostic implications are discussed. 相似文献