全文获取类型
收费全文 | 536篇 |
免费 | 36篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 7篇 |
儿科学 | 50篇 |
妇产科学 | 18篇 |
基础医学 | 51篇 |
口腔科学 | 9篇 |
临床医学 | 57篇 |
内科学 | 95篇 |
皮肤病学 | 10篇 |
神经病学 | 39篇 |
特种医学 | 25篇 |
外科学 | 100篇 |
综合类 | 7篇 |
预防医学 | 17篇 |
眼科学 | 19篇 |
药学 | 40篇 |
中国医学 | 20篇 |
肿瘤学 | 10篇 |
出版年
2023年 | 6篇 |
2022年 | 13篇 |
2021年 | 14篇 |
2020年 | 4篇 |
2019年 | 19篇 |
2018年 | 16篇 |
2017年 | 14篇 |
2016年 | 19篇 |
2015年 | 25篇 |
2014年 | 24篇 |
2013年 | 31篇 |
2012年 | 55篇 |
2011年 | 62篇 |
2010年 | 24篇 |
2009年 | 19篇 |
2008年 | 40篇 |
2007年 | 30篇 |
2006年 | 34篇 |
2005年 | 23篇 |
2004年 | 25篇 |
2003年 | 15篇 |
2002年 | 21篇 |
2001年 | 8篇 |
2000年 | 3篇 |
1999年 | 3篇 |
1998年 | 4篇 |
1997年 | 4篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1994年 | 4篇 |
1993年 | 1篇 |
1992年 | 3篇 |
1990年 | 1篇 |
1989年 | 2篇 |
1985年 | 1篇 |
1984年 | 1篇 |
1980年 | 2篇 |
1976年 | 1篇 |
1975年 | 1篇 |
排序方式: 共有574条查询结果,搜索用时 15 毫秒
61.
62.
63.
Evaluating the accuracy of functional biomarkers for detecting histological changes in chronic allograft nephropathy 总被引:1,自引:0,他引:1
Serdar Yilmaz Ipek Isik Marjan Afrouzian Mauricio Monroy Aylin Sar Hallgrimur Benediktsson Kevin McLaughlin 《Transplant international》2007,20(7):608-615
The most common cause of late kidney transplant failure is chronic allograft nephropathy (CAN). Much research has focused on identifying biomarkers (or correlates) that would predict subsequent CAN and allow timely intervention. Functional biomarkers such as serum creatinine and estimated glomerular filtration rate (eGFR) have been widely adopted, even though they have not been rigorously evaluated as surrogate markers. This study evaluated serum creatinine and eGFR for predicting the early histopathological changes seen in transplant protocol biopsies (TPB). We prospectively followed 289 kidney transplant patients in the Southern Alberta Transplant Program who had TPB at 6-12 months post-transplant. Tissue samples (n = 280) were independently examined by renal pathologists. The ability of serum creatinine or eGFR to predict the threshold level for abnormal histopathology was evaluated by calculating the area under the receiver operator characteristic curve. Serum creatinine and eGFR had poor predictive value (most confidence intervals included 0.5, indicating no predictive ability) for ten individual histological measurements (Banff 97 scores), and the Chronic Allograft Damage Index. We conclude that serum creatinine and eGFR have a limited clinical role in predicting the early histopathological changes that precede CAN and should not be used for this purpose. 相似文献
64.
Bacakoglu AK Kiray A Muratli K Ekin A Ergur I 《Anatomical science international / Japanese Association of Anatomists》2007,82(2):116-120
In the operative treatment of humeral shaft fractures the radial nerve may be injured during the reduction of fracture fragments or the application of plate and screws. Also, secondary surgical explorations due to delayed or non-union carry a high risk of radial nerve injury because of the scarring of the neighboring tissue and proximity of the nerve to the implants. Consequently, the need for the transposition of the radial nerve to a safer position arises. A total of 22 (11 right, 11 left) cadaveric upper extremities were studied to evaluate the medial transposition of the radial nerve during the open reduction and anterolateral plate fixation of humeral fractures. The radial nerve was transposed medially in a distal plate fixated humeral fracture model. Distance measurements of the radial nerve and the division points of its branches were carried out in the transposed position and in the original course of the nerve. There was no statistically significant difference between the original course and medially transposed measurements. The distances from the reference point to the division points of other branches (posterior antebrachial cutaneous nerve, motor branch to brachioradialis, most distal motor branch to triceps) were not altered. The mean length of the radial nerve was 185.2 +/- 14.3 mm in its original course and 183.7 +/- 13.8 mm in the medially transposed course. In conclusion, the present study shows that medial transposition of the radial nerve through the fracture line does not increase the nerve's length and may be utilized in cases in which anterolateral plate fixation is indicated. 相似文献
65.
66.
67.
Fibrinogen storage disease and cirrhosis associated with hypobetalipoproteinemia owing to fibrinogen Aguadilla in a Turkish child 下载免费PDF全文
68.
PURPOSE: As lateral sphincterotomy and anal dilatation causes complications, a reversible chemical sphincterotomy method has been recently proposed as an alternative treatment in patients with anal fissure. In this study, the effect of botulinum toxin causing temporary paralysis in internal anal sphincter was compared with that of lidocaine in patients with chronic anal fissure. METHOD: A total of 62 outpatients were randomly assigned to receive botulinum toxin or lidocaine pomade. The patients were evaluated before and after two months of treatment with physical examination and anal manometry. Pain and nocturnal pain were scored. RESULTS: In an evaluation period of two months, in 24 of 34 patients of botulinum group (70.58%), and in six of 28 patients of lidocaine group (21.42%) showed complete epithelization (p = 0.006). All patients who had previously reported nocturnal pain became symptom free in botulinum group and in four patients of lidocaine group. Pain following defecation disappeared in 24 patients of botulinum group and in 20 patients of control group (p = 0.959). There was no adverse effect in both groups. While resting anal pressure and maximum voluntary pressure were significantly low in botulinum toxin group, both parameters did not change in lidocaine group. CONCLUSIONS: Botulinum toxin is a reliable and effective method for patients with chronic anal fissure. It can be applied easily without any anesthesia and instrumentation. It is cheaper in comparison with surgical methods and it can be a good alternative treatment in patients with risk of incontinence. 相似文献
69.
70.
Purpose. To investigate the effectiveness of low-level laser therapy (LLLT) in addition to exercise programme on shoulder function in subacromial impingement syndrome (SAIS).Method. Sixty-seven patients with SAIS were randomly assigned to either a group that received laser (n = 34) or a group that received placebo Laser (n = 26). Pain, functional assessment, disability and muscle strength of shoulder were assessed before and after a 3-week rehabilitation programme. Besides Laser or placebo Laser, superficial cold and progressive exercise programme were administered to both groups, 5 days a week, for 3 weeks. A progressive exercise programme that was done daily twice under supervision in clinic and at home was given to the patients.Results. After the treatment, all outcome measurements had shown significant improvement except muscle strength in both the groups. When the parameters of the improvement were compared, there were no significant differences between the two groups after treatment.Conclusion. We concluded that there is no fundamental difference between LLLT and placebo LLLT when they are supplementing an exercise programme for rehabilitation of patients with shoulder impingement syndrome. 相似文献