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211.
Fructose absorption was studied by the breath hydrogen test in 114 healthy children aged 0.1-6 years, given either 2 g/kg or 1 g/kg of fructose. All 57 children given 2 g/kg had peak breath hydrogen excretions > or = 20 ppm. At 1 g/kg only 25/57 (44%) showed incomplete absorption and the percentage incompletely absorbing fructose and the peak breath hydrogen value were significantly higher in children aged 1-3 years. Interestingly, this age distribution correlates with that of toddler diarrhoea. 相似文献
212.
Bowel migration in the normal fetus: US detection 总被引:1,自引:0,他引:1
Cyr DR; Mack LA; Schoenecker SA; Patten RM; Shepard TH; Shuman WP; Moss AA 《Radiology》1986,161(1):119-121
Ten fetuses underwent ultrasound scanning at 7-10 weeks gestational (postmenstrual) age. In all cases, an echogenic mass measuring 0.5-1.0 cm was demonstrated within the base of the umbilical cord at its insertion into the fetal abdomen. No area with echogenicity characteristic of the small bowel was identified within the lower part of the fetal abdomen. All fetuses were reexamined 4-12 weeks later, at which time the mass in the umbilical cord was no longer seen, and normal fetal bowel was visualized in the lower abdominal cavity of the fetus. This sequence of findings appears to represent the sonographic demonstration of normal fetal bowel migration early in gestation and should not be confused with defects of the abdominal wall such as omphalocele or gastroschisis. 相似文献
213.
OM Al-Amro Al-Akloby† AA Al-Zayir‡ 《Journal of the European Academy of Dermatology and Venereology》2004,18(6):659-664
BACKGROUND: A total of 10 455 new dermatology patients were seen in the dermatology clinics of King Fahd Hospital of the University (KFHU), Al-Khobar, Eastern Saudi Arabia, between January 1990 and December 1995. We identified 21 patients with a histopathologically confirmed diagnosis of congenital nonbullous ichthyosiform erythroderma (CNBIE). We have reviewed the epidemiological and clinical features of these patients. OBJECTIVE: To document the epidemiological and clinical features of patients with CNBIE in eastern Saudi Arabia. METHODS: We used the dermatology outpatient department (OPD) logbooks to identify diagnosed cases of CNBIE from new patients presenting with different dermatological problems over a 6-year period. We used specifically designed data-collection protocol forms to extract epidemiological and clinical data from the patients' medical records. These were entered into a computer database and analysed using standard statistical software. RESULTS: A total of 21 patients (five males, 16 females) with a male : female ratio of 0.31 : 1 were identified from a total of 10 455 new patients seen in our dermatology clinics over the study period. The occurrence rate of CNBIE in our clinics was 0.2%, or two per 1000 new dermatology cases. Nineteen (90%) of 21 CNBIE patients were born with collodion membranes. Eighty-one per cent of our patients had a positive family history of CNBIE. Consanguinity among the parents of our CNBIE patients was significantly high at 95%. CONCLUSIONS: To the best of our knowledge, this preliminary study is the first report of its kind from Saudi Arabia (documenting the clinico-epidemiological features of CNBIE patients in the Eastern Province). The high rate of parental consanguinity among the parents of our Saudi CNBIE patients may account for the high incidence rate of this genodermatosis in eastern Saudi Arabia. In comparison with results of other studies that reported a low occurrence rate of CNBIE among dermatology patients, our results were of a significantly higher rate. 相似文献
214.
盛瑞兰 《南京医科大学学报(英文版)》1994,(1)
DetectionofImmunoglobulinHeavyChianandTCellReceptorγGeneRearrangementinLymphNodeAspirateswithPCR:DiagnosticSignificanceforLym... 相似文献
215.
The medical records of all patients discharged over a 3-year period with a diagnosis of pancreatic insufficiency were reviewed. In some patients, abdominal radiographs or sonograms provided adequate information. However, computed tomography (CT) was a key diagnostic tool in understanding the cause of pancreatic insufficiency in 11 of the 13 patients in whom it was performed. CT study detected previously undiagnosed carcinoma in one patient, enabled diagnosis of chronic pancreatitis in five, confirmed complete surgical removal of the pancreas in two, and--despite optimal use of contrast material and 5-mm contiguous sections--was unable to detect any pancreatic tissue in three patients, suggesting complete idiopathic atrophy. Pancreatic insufficiency is a difficult clinical diagnostic problem. CT scanning should be employed early if abdominal radiographs or sonograms do not detect an abnormality. 相似文献
216.
Using a flow model that simulated the inferior vena cava (IVC), the authors conducted an in vitro comparison of the Mobin-Uddin (MU), Kimray-Greenfield (KG), Amplatz spider (A), Günther basket (G), Simon nitinol (SN), and bird's nest (BN) filters. The following parameters were evaluated: clot-trapping capacity and flow dynamics, which included measurements of pressure gradients across filters and assessment of flow patterns. The MU, A, G, SN, and BN filters trapped an average of 80%-100% of small clots and 100% of large clots. The KG filter, in a central position, trapped 0%-10% of small clots and 60%-100% of larger clots. In the eccentric position, the KG filter trapped only 20% of all clots. The BN and SN filters showed the least flow turbulence. Moderate turbulence was observed with the G and KG filters, while the MU and A filters showed marked turbulence. The current standard KG filter allowed the passage of small and large clots. When specific parameters were considered--such as clot-trapping capacity and flow-dynamic performance--the BN, SN, and G IVC filters were superior to the other filters that were tested. 相似文献
217.
AA Carmine 《药学实践杂志》1986,(2):6-7
哌仑西平(Pirenzepine)为吡啶并苯二氮(?)类抗胆碱能化合物,其结构与丙咪嗪有关。然而,它是一个“选择性”抗毒蕈碱药,由于它难于透入中枢神经系统,基本上没有中枢活性。药效学研究动物研究表明,对于毒蕈碱受体位点哌仑西平是乙酰胆碱的竞争性抑制剂,在等摩 相似文献
218.
We have previously shown that circulating progenitor cells in patients with polycythemia vera (PV) are hypersensitive to insulin-like growth factor I (IGF-I) with respect to erythroid burst formation in serum- free medium, and that this effect occurs through the IGF-I receptor. To investigate the molecular basis of this IGF-I hypersensitivity phenomenon, we examined tyrosine phosphorylation of the IGF-I receptor beta subunit in peripheral blood mononuclear cells (PBMNC) from eight PV patients and six normals. Cells were exposed to IGF-I at concentrations of 10(-8) and 10(-10) mol/L for 0, 1, 3, and 10 minutes, and then lysed. The IGF-I receptor beta subunit was immunoprecipitated, and the protein was resolved by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blotted with antiphosphotyrosine antibody (4G10). We found that, in the absence of exogenous IGF-I, there was a basal level of tyrosine phosphorylation of the IGF-I receptor beta subunit, and it was substantially greater in PV than in normal. At 10(-10) mol/L IGF-I in normals, no evidence of increased tyrosine phosphorylation was detected; however in PV, a pronounced increase in tyrosine phosphorylation was observed at both 10(-10) and 10(-8) mol/L IGF-I, and it occurred earlier and attained a higher level than in normal. In contrast, in PBMNC from three patients with erythrocytosis, no significant increase above normal was seen in either basal or induced tyrosine phosphorylation of the IGF-I receptor beta subunit. Thus, our findings show two distinctive features of the PV phenotype in PBMNC: (1) an increased basal tyrosine phosphorylation of the IGF-I receptor beta subunit, and (2) a hypersensitive and hyperresponsive receptor with respect to tyrosine phosphorylation. These features may influence the ability of the receptor to transmit a proliferative signal; thus, they may play a role in the pathogenesis of PV. 相似文献
219.
AA Vein JG van Dijk MD Ferrari 《Cephalalgia : an international journal of headache》2004,24(10):910-911
220.