全文获取类型
收费全文 | 1036123篇 |
免费 | 71805篇 |
国内免费 | 1871篇 |
专业分类
耳鼻咽喉 | 13956篇 |
儿科学 | 31457篇 |
妇产科学 | 28198篇 |
基础医学 | 140910篇 |
口腔科学 | 27342篇 |
临床医学 | 87588篇 |
内科学 | 195255篇 |
皮肤病学 | 17795篇 |
神经病学 | 86324篇 |
特种医学 | 43823篇 |
外国民族医学 | 171篇 |
外科学 | 164515篇 |
综合类 | 26924篇 |
现状与发展 | 2篇 |
一般理论 | 267篇 |
预防医学 | 84356篇 |
眼科学 | 23315篇 |
药学 | 74121篇 |
中国医学 | 2240篇 |
肿瘤学 | 61240篇 |
出版年
2018年 | 28597篇 |
2017年 | 22599篇 |
2016年 | 25468篇 |
2015年 | 8801篇 |
2014年 | 12078篇 |
2013年 | 17810篇 |
2012年 | 29853篇 |
2011年 | 44381篇 |
2010年 | 32083篇 |
2009年 | 24378篇 |
2008年 | 41582篇 |
2007年 | 45699篇 |
2006年 | 25288篇 |
2005年 | 26484篇 |
2004年 | 27226篇 |
2003年 | 27207篇 |
2002年 | 24514篇 |
2001年 | 36129篇 |
2000年 | 36884篇 |
1999年 | 31079篇 |
1998年 | 9445篇 |
1997年 | 8788篇 |
1996年 | 8579篇 |
1995年 | 8128篇 |
1994年 | 7835篇 |
1992年 | 26711篇 |
1991年 | 26204篇 |
1990年 | 25756篇 |
1989年 | 24767篇 |
1988年 | 23281篇 |
1987年 | 22943篇 |
1986年 | 21772篇 |
1985年 | 21143篇 |
1984年 | 16422篇 |
1983年 | 14031篇 |
1982年 | 8896篇 |
1981年 | 8216篇 |
1979年 | 16748篇 |
1978年 | 12135篇 |
1977年 | 10199篇 |
1976年 | 9354篇 |
1975年 | 10171篇 |
1974年 | 12665篇 |
1973年 | 12151篇 |
1972年 | 11550篇 |
1971年 | 10691篇 |
1970年 | 10242篇 |
1969年 | 9934篇 |
1968年 | 8920篇 |
1967年 | 8235篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
191.
Metoclopramide, a substituted benzamide derivative, was orally administered to a patient with intractable hiccups. Dysphoria, akathisia, depressed mood with suicidal ideation, insomnia, racing thoughts, and labile affect were seen following the administration of metoclopramide. The episode met criteria for an organic affective syndrome. It is suggested that the mental status of patients undergoing metoclopramide therapy be monitored, since these symptoms have not been previously reported. 相似文献
192.
193.
194.
Donor interleukin-4 promoter gene polymorphism influences allograft rejection after heart transplantation. 总被引:3,自引:0,他引:3
Femke J Bijlsma Joyce vanKuik Marcel G J Tilanus Nicolaas deJonge Erik H Rozemuller Jan G van den Tweel Frits H J Gmelig-Meyling Roel A deWeger 《The Journal of heart and lung transplantation》2002,21(3):340-346
BACKGROUND: The cytokine interleukin-4 (IL-4) is secreted mainly by activated T lymphocytes and characterizes the T-helper 2 (Th2) sub-type. In transplantation Th2 cells are believed to induce graft tolerance. Previous studies revealed that patients with a relatively high frequency of IL-4 producing helper T lymphocytes (HTL) before heart transplantation (HTX) had no or less rejection episodes compared with patients with a low frequency of IL-4 producing HTL. Three single nucleotide polymorphisms (SNPs) have been identified in the promoter region of the IL-4 gene, which influence promoter strength. We investigated whether there was a correlation between SNP genotypes in the IL-4 promoter and heart failure, and rejection after HTX. METHODS: Seventy HTX patients, 61 donors, and 36 controls were genotyped for the 3 SNPs by sequencing. RESULTS: Of the SNPs at -285 and -81, only the C and A alleles, respectively, were found in this study. Both alleles were found for the -590 SNP. No relation between patient genotype of the SNP at -590 and heart failure and rejection was found. However, incidence of rejection was significantly lower in patients that received a donor heart with the T-positive genotype compared with patients that received a heart from a T-negative donor. Patients who had the T-negative genotype and received a heart from a T-positive donor, suffered significantly less from rejection than T-negative patients that received a T-negative donor heart. This was not significant in the T-positive patient group. CONCLUSIONS: This indicates that IL-4 production within the donor heart and by cells from the donor is important for reducing incidence of episodes of rejection. 相似文献
195.
196.
197.
The efficacy of radiology in evaluating dysphagia was studied in 86 patients by comparison to endoscopic findings. In the 66 patients with endoscopic abnormalities radiology was correct in 54, for a sensitivity of 82%. Sensitivity of radiology improved to 95% if mild esophagitis was excluded. In the 20 patients with normal endoscopy, radiology was normal in 18 (90%). Thus radiology proved to be a reliable means of evaluating the esophagus in patients with dysphagia. 相似文献
198.
P Tugwell L Hart G Kraag A Park C Dok F Bianchi C Goldsmith W W Buchanan 《The Journal of rheumatology》1984,11(4):457-461
A crossover double-blind controlled trial was performed on 36 patients with rheumatoid arthritis to assess the necessity for serum salicylate monitoring in determining optimal dosage. There was no clinically or statistically significant increase in the clinical improvement of patients associated with serum monitoring but potentially toxic serum levels occurred without tinnitus when serum monitoring was not used. 相似文献
199.
200.