全文获取类型
收费全文 | 3724篇 |
免费 | 171篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 17篇 |
儿科学 | 95篇 |
妇产科学 | 84篇 |
基础医学 | 380篇 |
口腔科学 | 113篇 |
临床医学 | 268篇 |
内科学 | 1103篇 |
皮肤病学 | 43篇 |
神经病学 | 187篇 |
特种医学 | 199篇 |
外科学 | 689篇 |
综合类 | 9篇 |
预防医学 | 113篇 |
眼科学 | 13篇 |
药学 | 191篇 |
中国医学 | 6篇 |
肿瘤学 | 408篇 |
出版年
2023年 | 21篇 |
2022年 | 42篇 |
2021年 | 80篇 |
2020年 | 35篇 |
2019年 | 54篇 |
2018年 | 79篇 |
2017年 | 67篇 |
2016年 | 70篇 |
2015年 | 57篇 |
2014年 | 97篇 |
2013年 | 128篇 |
2012年 | 214篇 |
2011年 | 215篇 |
2010年 | 145篇 |
2009年 | 101篇 |
2008年 | 177篇 |
2007年 | 233篇 |
2006年 | 219篇 |
2005年 | 254篇 |
2004年 | 207篇 |
2003年 | 182篇 |
2002年 | 188篇 |
2001年 | 91篇 |
2000年 | 90篇 |
1999年 | 87篇 |
1998年 | 39篇 |
1997年 | 21篇 |
1996年 | 21篇 |
1995年 | 36篇 |
1994年 | 33篇 |
1993年 | 27篇 |
1992年 | 62篇 |
1991年 | 51篇 |
1990年 | 68篇 |
1989年 | 43篇 |
1988年 | 37篇 |
1987年 | 32篇 |
1986年 | 31篇 |
1985年 | 41篇 |
1984年 | 19篇 |
1983年 | 18篇 |
1979年 | 28篇 |
1978年 | 15篇 |
1976年 | 15篇 |
1975年 | 14篇 |
1974年 | 15篇 |
1973年 | 15篇 |
1972年 | 12篇 |
1971年 | 11篇 |
1968年 | 12篇 |
排序方式: 共有3918条查询结果,搜索用时 15 毫秒
991.
Koide M Ito K Taniguchi T Yokoi H Nakamura R Irie H Kinoshita N Hashimoto T Tamaki S Sawada T Azuma A Matsubara H 《Kaku igaku. The Japanese journal of nuclear medicine》2006,43(1):1-6
A 97-year-old woman was provoked a convulsion after taking a new quinolone antibiotic drug Levofloxacin and a non-steroidal anti-inflammatory drug Loxoprofen. At a later time, she was suffered from severe chest pain. An electrocardiogram showed ST segment elevation in leads II, III and aVF, and T-wave inversion in leads V1 to V4. Coronary angiography demonstrated no organic stenosis, however biventriculography revealed apical ballooning akinesis and basal hyperkinesis. Positron emission tomography was also performed to assess the uptake of 18F-fluorodeoxyglucose (FDG) after 75 g oral glucose loading for evaluating myocardial glucose metabolism at 10th day. Severely reduced uptake of FDG was observed in the apical ballooning region. Left ventriculography showed normal wall motion at 19th day. Thallium-201 myocardial single-photon emission computed tomography (SPECT) to determine the status of myocardial perfusion at the 20th hospital day showed normal perfusion. Iodine-123-beta-methyl-p-iodophenyl penta-decanoic acid myocardial SPECT to evaluate myocardial fatty acid metabolism at the 23rd day revealed severely reduced uptake in the apical ballooning region. These findings suggested that the coronary microcirculation was impaired in the apical ballooning region. 相似文献
992.
993.
Eisuke Shiozawa Tomoko Norose Kazuhiro Kaneko Toshiko Yamochi-Onizuka Masafumi Takimoto Michio Imawari Hidekazu Ota 《Journal of gastroenterology and hepatology》2009,24(2):307-315
Background and Aim: The World Health Organization (WHO) has adopted criteria for the histological differential diagnosis of gastric extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (GML) based on the criteria proposed by Wotherspoon in 1993 (WHO/Wotherspoon score). These histological criteria are commonly used by pathologists for initial diagnoses, but have not been adopted uniformly for the post-treatment evaluation of GML. In 2003, the Groupe d'Etude des Lymphomes de l'Adult (GELA) proposed a new histological grading system (GELA grade) in preference to use of the WHO/Wotherspoon score for post-treatment evaluation. In the present study, we compared the WHO/Wotherspoon and GELA systems to examine which histological criterion is better for post-treatment evaluation.
Methods: Fourteen cases of GML under long-term follow up were initially diagnosed according to the WHO criteria with detailed immunohistology, and were periodically evaluated with both histological criteria after anti- Helicobacter pylori treatment. They were also evaluated based on histological stromal changes accompanying the disappearance of lymphoma tissue.
Results: The study showed strong similarities between the WHO/Wotherspoon and GELA systems and no clear advantage of either system for post-treatment evaluation. The GELA grade could not be used for the evaluation of changes in the degree of lymphoma infiltration from pre- to post-treatment because the four-item scale is not comparable with the formal six-point WHO/Wotherspoon scale. Stromal changes in the lamina propria, including an empty appearance and fibrosis, were correlated with lymphoma reduction after treatment and appear to be good indicators for post-treatment evaluation.
Conclusion: We propose the utilization of the WHO/Wotherspoon score accompanied by the assessment of stromal changes for the post-treatment evaluation of GML. 相似文献
Methods: Fourteen cases of GML under long-term follow up were initially diagnosed according to the WHO criteria with detailed immunohistology, and were periodically evaluated with both histological criteria after anti- Helicobacter pylori treatment. They were also evaluated based on histological stromal changes accompanying the disappearance of lymphoma tissue.
Results: The study showed strong similarities between the WHO/Wotherspoon and GELA systems and no clear advantage of either system for post-treatment evaluation. The GELA grade could not be used for the evaluation of changes in the degree of lymphoma infiltration from pre- to post-treatment because the four-item scale is not comparable with the formal six-point WHO/Wotherspoon scale. Stromal changes in the lamina propria, including an empty appearance and fibrosis, were correlated with lymphoma reduction after treatment and appear to be good indicators for post-treatment evaluation.
Conclusion: We propose the utilization of the WHO/Wotherspoon score accompanied by the assessment of stromal changes for the post-treatment evaluation of GML. 相似文献
994.
995.
996.
Hidekazu Fujimaki Yoshika Kurokawa Shoji Yamamoto Masahiko Satoh 《Immunopharmacology and immunotoxicology》2013,35(4):703-714
To clarify the possible role of interleukin-6 in aggravation of inflammatory responses in diesel exhaust-exposed mice, we compared the infiltration of inflammatory cells and the production of chemokines between interleukin-6-deficient and wild-type mice following 0, 1.0, or 3.0 mg diesel particles/m3 diesel exhaust inhalation for 4 weeks. Exposure to diesel exhaust significantly increased the number of inflammatory cells and the amount of CCL17 and CXCL3 in bronchoalveolar lavage fluids from wild-type mice, but not in interleukin-6-deficient mice. These findings suggest that interleukin-6 plays a critical role in airway inflammatory responses induced by diesel exhaust inhalation. 相似文献
997.
Hidekazu Hirai Toshihiko Shibata Yasuyuki Sasaki Hiromichi Fujii Shoji Kubo Shigefumi Suehiro 《General thoracic and cardiovascular surgery》2010,58(5):235-238
A 38-year-old man had Stanford type B chronic aortic dissection. Blood pressure was diffi cult to control, and further examination
revealed primary aldosteronism. Magnetic resonance images showed a 1-cm nodule in the left adrenal gland. Graft replacement
for aortic dissection under extracorporeal circulation and resection of the left adrenal gland were undertaken simultaneously.
The postoperative course was uneventful, and blood pressure was controlled without antihypertensive drugs. 相似文献
998.
999.
Yukio Obitsu Nobusato Koizumi Naozumi Saiki Satoshi Kawaguchi Hiroshi Shigematsu 《Journal of cardiothoracic surgery》2010,5(1):28
We herein present a 60 years old woman with Takayasu arteritis and an extensive thoracic aortic aneurysm who initially underwent
a total aortic arch replacement. Then, in the second stage, thoracic endovascular aortic repair was performed using the elephant
trunk graft as the proximal landing zone at four weeks after aortic arch repair. The postoperative course was relatively uncomplicated,
but a type II endoleak was noted. Currently, about 5 years postoperatively, the slight type II endoleak from intercostal artery
persists, but aneurism dilatation has not been noted, so the patient is being followed up. 相似文献
1000.