全文获取类型
收费全文 | 859篇 |
免费 | 63篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 87篇 |
妇产科学 | 10篇 |
基础医学 | 121篇 |
口腔科学 | 21篇 |
临床医学 | 113篇 |
内科学 | 185篇 |
皮肤病学 | 21篇 |
神经病学 | 51篇 |
特种医学 | 111篇 |
外科学 | 90篇 |
综合类 | 10篇 |
预防医学 | 47篇 |
眼科学 | 2篇 |
药学 | 29篇 |
中国医学 | 1篇 |
肿瘤学 | 24篇 |
出版年
2021年 | 10篇 |
2020年 | 6篇 |
2019年 | 14篇 |
2018年 | 13篇 |
2017年 | 12篇 |
2016年 | 12篇 |
2015年 | 21篇 |
2014年 | 16篇 |
2013年 | 43篇 |
2012年 | 28篇 |
2011年 | 26篇 |
2010年 | 36篇 |
2009年 | 38篇 |
2008年 | 23篇 |
2007年 | 17篇 |
2006年 | 14篇 |
2005年 | 16篇 |
2004年 | 13篇 |
2003年 | 10篇 |
2002年 | 17篇 |
2001年 | 19篇 |
2000年 | 9篇 |
1999年 | 11篇 |
1998年 | 24篇 |
1997年 | 32篇 |
1996年 | 31篇 |
1995年 | 33篇 |
1994年 | 28篇 |
1993年 | 45篇 |
1992年 | 10篇 |
1991年 | 15篇 |
1990年 | 18篇 |
1989年 | 21篇 |
1988年 | 24篇 |
1987年 | 18篇 |
1986年 | 18篇 |
1985年 | 15篇 |
1984年 | 9篇 |
1982年 | 12篇 |
1981年 | 18篇 |
1980年 | 9篇 |
1978年 | 15篇 |
1977年 | 10篇 |
1976年 | 18篇 |
1975年 | 5篇 |
1973年 | 6篇 |
1971年 | 5篇 |
1969年 | 7篇 |
1968年 | 8篇 |
1966年 | 7篇 |
排序方式: 共有924条查询结果,搜索用时 15 毫秒
71.
72.
73.
Stephanie Ogden Miny Samuel Christopher EM Griffiths 《Clinical Interventions in Aging》2008,3(1):71-76
Chronic sun exposure leads to photodamage, which is characterized clinically by fine and coarse wrinkles, dyspigmentation, telangiectasia, laxity, roughness and a sallow appearance. Many treatments claim to reduce the signs of photodamage, however evidence from randomized controlled trials (RCT) to support these claims is limited. The use of topical retinoids, particularly tretinoin, isotretinoin and tazarotene, has been shown to significantly reduce signs of photodamage both clinically and histologically. Over recent years a number of RCTs, have affirmed that topical tazarotene is an effective and safe treatment for photodamaged skin. 相似文献
74.
Serial cranial sonograms of 55 neonates with large perinatal intraventricular/intraparenchymal hemorrhages and moderate-to-severe posthemorrhagic hydrocephalus were reviewed. In all 55 patients, the ventricles were initially enlarged and filled with anechoic cerebrospinal fluid, which contained discrete hyperechoic fragments of hematoma. Between 7 and 25 days after the initial hemorrhagic episode, however, diffuse, low-level echogenicity appeared in the ventricles of 34 patients. The low-level echogenicity was transient and persisted for 7-59 days (average, 18 days). In 32 patients, low-level echogenicity was a benign finding associated with prior intraventricular hemorrhage. In two patients, the low-level echogenicity was associated with ventriculitis. Low-level echogenicity appeared, increased, then cleared, but reappeared with the onset of ventriculitis in these two patients. Thickening of the ependyma and abnormal periventricular echogenicity, signs of inflammation, were also present. Although low-level echogenicity may commonly be a benign finding, the possibility of ventriculitis should not be ignored. 相似文献
75.
C Neoh FCOphth A Agius-Fernandez FCOphth SB Kaye MD FCOphth EM Molyneux MRCP CA Hart PhD MRCPath 《International journal of clinical practice》1994,48(1):27-28
SUMMARY Four cases of primary meningococcal conjunctivitis in children are reported. This represents an incidence of 2% of patients presenting with conjunctivitis to a paediatric A&E department. All were initially treated with topical chloramphenicol, followed by systemic rifampicin once the diagnosis had been established. No ocular or systemic complications developed, nor recolonisation of the conjunctiva or colonisation of the nasopharynx at follow-up (1–2 years). 相似文献
76.
A modified Western blot (WB) that includes both shared (r21e) and unique recombinant envelope proteins from human T-lymphotropic virus (HTLV) type I (rgp46I) and type II (rgp46II) was compared to conventional HTLV serologic tests in 379 United States blood donors and individuals residing in diverse geographic regions, and the specimens were categorized as positive (n = 158), indeterminate (n = 158), or negative (n = 63) for HTLV infection. Of the 158 HTLV-I/II-positive specimens (66 requiring radioimmunoprecipitation assay [RIPA] for confirmation), 156 reacted concordantly with r21e, gag, and either rgp46I or rgp46II, thus eliminating the need for RIPA in all but two specimens and yielding a test sensitivity of 98.7 percent. Of the 158 indeterminate and 63 negative specimens, none reacted with r21e and rgp46I or rgp46II, yielding a test specificity of 100 percent. Furthermore, analysis of an additional 184 consecutive specimens from a retrovirology reference laboratory demonstrated that the modified WB correctly identified 27 of 28 HTLV-I specimens and all 13 HTLV-II specimens, with a test sensitivity of 97.6 percent. None of specimens that were indeterminate or nonreactive in conventional WB and/or RIPA and none of the screening enzyme immunoassay-negative specimens reacted with r21e and either rgp46I or rgp46II, for a test specificity of 100 percent. Thus, the modified WB appears to be highly sensitive and specific for simultaneous detection and discrimination of HTLV-I from HTLV-II and has the advantage of being a one-step assay that is easily performed in all types of laboratory settings and allows rapid, reliable, and standardized testing for HTLV-I/II infection. 相似文献
77.
J. L. Srensen E. N. Hauge H. Wroblewski F. Biering-Srensen 《Clinical physiology and functional imaging》1994,14(3):281-289
Summary. In a methodological study including 14 paraplegics and seven normal controls cutaneous and subcutaneous blood flow rates were investigated by 133Xenon wash-out after atraumatic labelling. In paraplegics, areas suffering pressure sores were included. The method was found applicable for the authors' purposes. In seven paraplegics median (95% confidence limits) cutaneous blood flow was 5–2 (2–4–8–5) ml (100 g min)“1 and subcutaneous 4–3 (2–0–13–2) ml (100 g min)-1. This did not differ from normal controls. In seven paraplegics with ischial pressure sores a trend for increased cutaneous blood-flow rates from areas adjacent to sores was obvious (P= 0–06). During 704 head-up tilt, elimination-rate constants were reduced by a factor of 0–54 (0–50–0–70). A proximal blockade or infiltration of the 133Xenon depots with lidocaine did not inhibit employment of the method. The proximal block did not alter the local blood flow rate, but infiltration increased it in both paraplegics and normal individuals. Intra- and interdepot coefficients of variation were about 11% and 40% respectively. Interindividual coefficients of variation varied between 25% and 46%. 相似文献
78.
One hundred nulliparous college female undergraduates were randomly assigned to a series of 10 treatment groups that comprised a variety of cognitive-behavioral pain-coping strategies designed as part of a labor preparation analogue. The efficacy of these treatments was subsequently assessed during a one-hour session involving twenty 80-sec exposures to a laboratory pain stimulus patterned to resemble labor contractions. Dependent variables included self-reported pain, systolic and diastolic blood pressure, frontalis EMG, and heart rate. One of the cognitive strategies--sensory transformation--was found to have a significant effect on self-reported pain. Analyses conducted on the other five dependent variables failed to show significant treatment effects. 相似文献
79.
EM Keane MRCGP DOM H Wilson MPS D McGrane MB BCh D Coakley MD JB Walsh FRCP 《International journal of clinical practice》1995,49(2):71-72
SUMMARY In this test a course of 4 drops twice a day for 5 days of ear wax solvents, a cerumenolytic, sodium bicarbonate, or sterile water significantly increased the clearance of wax from ears by natural expulsion and eliminated the requirement for ear syringing in 50% of cases. 相似文献
80.
CR Valeri G Ragno LE Pivacek R Srey JR Hess LE Lippert F Mettille R Fahie EM O''Neill IO Szymanski 《Transfusion》2002,42(12):1618-1618