全文获取类型
收费全文 | 7850篇 |
免费 | 406篇 |
国内免费 | 35篇 |
专业分类
耳鼻咽喉 | 127篇 |
儿科学 | 403篇 |
妇产科学 | 206篇 |
基础医学 | 814篇 |
口腔科学 | 184篇 |
临床医学 | 649篇 |
内科学 | 1764篇 |
皮肤病学 | 143篇 |
神经病学 | 567篇 |
特种医学 | 246篇 |
外科学 | 1561篇 |
综合类 | 166篇 |
一般理论 | 2篇 |
预防医学 | 356篇 |
眼科学 | 178篇 |
药学 | 482篇 |
中国医学 | 32篇 |
肿瘤学 | 411篇 |
出版年
2023年 | 67篇 |
2022年 | 208篇 |
2021年 | 316篇 |
2020年 | 191篇 |
2019年 | 219篇 |
2018年 | 260篇 |
2017年 | 171篇 |
2016年 | 220篇 |
2015年 | 234篇 |
2014年 | 340篇 |
2013年 | 469篇 |
2012年 | 609篇 |
2011年 | 606篇 |
2010年 | 346篇 |
2009年 | 287篇 |
2008年 | 453篇 |
2007年 | 497篇 |
2006年 | 481篇 |
2005年 | 427篇 |
2004年 | 400篇 |
2003年 | 347篇 |
2002年 | 282篇 |
2001年 | 97篇 |
2000年 | 82篇 |
1999年 | 67篇 |
1998年 | 37篇 |
1997年 | 21篇 |
1996年 | 31篇 |
1995年 | 37篇 |
1994年 | 30篇 |
1993年 | 29篇 |
1992年 | 44篇 |
1991年 | 51篇 |
1990年 | 28篇 |
1989年 | 43篇 |
1988年 | 29篇 |
1987年 | 21篇 |
1986年 | 24篇 |
1985年 | 20篇 |
1984年 | 18篇 |
1983年 | 15篇 |
1982年 | 8篇 |
1981年 | 21篇 |
1980年 | 14篇 |
1979年 | 10篇 |
1978年 | 9篇 |
1977年 | 10篇 |
1973年 | 7篇 |
1972年 | 6篇 |
1967年 | 12篇 |
排序方式: 共有8291条查询结果,搜索用时 15 毫秒
101.
Yilmaz HH Yildirim D Ugan Y Tunc SE Yesildag A Orhan H Akdag C 《Rheumatology international》2012,32(5):1171-1178
The aim of this study was to investigate the clinical, radiographic, and magnetic resonance imaging (MRI) findings of temporomandibular
joint (TMJ) and masticatory muscles in rheumatoid arthritis (RA) patients. Twenty-eight RA patients and 29 healthy subjects
were participated in the study. The patient underwent clinical and laboratory investigation. DAS28 scores were calculated.
Lateral panoramic radiography was performed to evaluate condylar erosion and condylar movement. Craniofacial MRI was performed
to evaluate TMJ and masseter, medial and lateral pterygoid muscles’ thickness, and cross-sectional area. It was found that
the mean maximal interincisal distance, range of lateral, retrusive (P < 0.05) and protrusive motion were all lesser in RA group. Lateral panoramic radiography revealed a distinct erosion in 10.7%
(3/28) and restricted condylar movement in 53.6% (15/28) of RA patients. Two RA patients demonstrating marked condylar erosion
in lateral panoramic radiographs were RF negative and had DAS28 scores 3.41 and 4.61. MRI findings revealed condylar erosion
and effusion in one RA patient and atrophic changes of masticatory muscles in another patient. There was no statistical significance
between RA and healthy groups for the thickness and cross-sectional areas of the masticatory muscles. RA group revealed a
strong linear relationship for the right and left muscle thickness and cross-sectional areas in regression analysis. TMJ symptoms
are frequent findings and thought to be affected from mean disease duration in RA. Laboratory findings should be considered
for disease activity–related TMJ involvement. RA patients did not present muscular atrophy or hypertrophy. 相似文献
102.
Güzel A Günaydin M Güzel A Alaçam H Murat N Gacar A Güvenç T 《Experimental lung research》2012,38(3):147-156
Aspiration is a serious complication of gastrointestinal (GI) decontamination procedure. Studies have shown that tumor necrosis factor-α (TNF-α) blockers have beneficial effects on lung injury. Therefore, the authors investigated the attenuation by infliximab (INF) on activated charcoal (AC)- and polyethylene glycol (PEG)-induced lung injury in rat model. Forty-two male Sprague-Dawley rats were allotted into 1 of 6 groups: saline (NS), activated charcoal (AC), polyethylene glycol (PEG), NS+INF treated, AC+INF treated, and PEG+INF treated. All materials were aspirated into the lungs at a volume of 1 mL/kg. Before aspiration, the rats were injected subcutaneously with INF. Seven days later, both lungs and serum specimens in all groups were evaluated histopathologically, immunohistochemically, and biochemically. Following aspiration of AC and PEG, evident histopathological changes were assigned in the lung tissue that were associated with increased expression of inducible nitric oxide synthase (iNOS), increased serum levels of oxidative stress markers (malondialdehyde [MDA], surfactant protein-D [SP-D], TNF-α), and decreased antioxidant enzyme (glutathione peroxidase [GSH-Px]) activities. INF treatment significantly decreased the elevated serum MDA and TNF-α levels and increased serum GSH-Px levels. Furthermore, the current results show that there is a significant reduction in the activity of iNOS in lung tissue and increased serum SP-D levels of AC and PEG aspiration-induced lung injury with INF treatment. These findings suggest that INF attenuates lung inflammation and prevents GI decontamination agent-induced lung injury in rats. 相似文献
103.
Marchaim D Chopra T Bogan C Bheemreddy S Sengstock D Jagarlamudi R Malani A Lemanek L Moshos J Lephart PR Ku K Hasan A Lee J Khandker N Blunden C Geffert SF Moody M Hiro R Wang Y Ahmad F Mohammadi T Faruque O Patel D Pogue JM Hayakawa K Dhar S Kaye KS 《American journal of infection control》2012,40(8):760-765
104.
105.
A. C. Papanicolaou K. M. Hasan C. Boake Thomas J. Eluvathingal L. Kramer 《Neurocase》2013,19(4):226-228
We report a case of episodic amnesia in which the anatomical basis of injury was investigated by diffusion tensor imaging (DTI). Two months after an adult male suffered severe closed head injury, conventional magnetic resonance imaging (CMRI) revealed only a right superior frontal lesion. However, 14 years later, DTI revealed structural anomalies not visible on CMRI involving limbic white matter tracts, notably the fornix, which could explain the amnesia. 相似文献
106.
107.
Ahmet Bacaksiz Mehmet Akif Vatankulu Mehmet Kayrak Hasan Huseyin Telli Selim S. Ayhan Osman Sonmez Ayse Alp Sadik Buyukbas 《Clinics (S?o Paulo, Brazil)》2013,68(7):997-1003
OBJECTIVES:
Acute ST-elevation myocardial infarction is associated with ventricular dysfunction due to ischemia-induced progressive myocardial damage. The decrease in ventricular compliance causes left atrial dilatation and stretching of the atrial myocardium, which are the main stimuli for the secretion of atrial natriuretic peptide. The aim of this study was to evaluate left atrial dimensions and atrial natriuretic peptide levels in patients early after their first acute ST-elevation myocardial infarction and assess the probable interaction between coronary lesions and these measurements.METHODS:
A total of 110 patients with acute myocardial infarction and 50 controls were studied. Plasma atrial natriuretic peptide was measured at admission. Left ventricular function, diameter, and volume index were evaluated using transthoracic echocardiography. Gensini and vessel scores of the patients who underwent coronary angiography were calculated.RESULTS:
Plasma atrial natriuretic peptide in the patients with myocardial infarction was increased compared with that in controls (3.90±3.75 vs. 1.35±0.72 nmol/L, p<0.001). Although the left atrial diameter was comparable in patients and controls, the left atrial volume index was increased in patients with acute myocardial infarction (26.5±7.1 vs. 21.3±4.9 mL/m2, p<0.01). Multivariate regression analysis showed a strong independent correlation between the left atrial volume index and the plasma atrial natriuretic peptide level (β = 0.23, p = 0.03).CONCLUSIONS:
The left atrial volume index and plasma atrial natriuretic peptide level were correlated in patients with acute myocardial infarction. 相似文献108.
109.
110.