全文获取类型
收费全文 | 1658篇 |
免费 | 122篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 26篇 |
儿科学 | 51篇 |
妇产科学 | 10篇 |
基础医学 | 207篇 |
口腔科学 | 115篇 |
临床医学 | 233篇 |
内科学 | 235篇 |
皮肤病学 | 17篇 |
神经病学 | 140篇 |
特种医学 | 70篇 |
外科学 | 271篇 |
综合类 | 8篇 |
一般理论 | 2篇 |
预防医学 | 207篇 |
眼科学 | 15篇 |
药学 | 100篇 |
肿瘤学 | 80篇 |
出版年
2023年 | 11篇 |
2022年 | 17篇 |
2021年 | 25篇 |
2020年 | 30篇 |
2019年 | 34篇 |
2018年 | 38篇 |
2017年 | 43篇 |
2016年 | 58篇 |
2015年 | 53篇 |
2014年 | 87篇 |
2013年 | 74篇 |
2012年 | 105篇 |
2011年 | 118篇 |
2010年 | 67篇 |
2009年 | 56篇 |
2008年 | 113篇 |
2007年 | 122篇 |
2006年 | 103篇 |
2005年 | 91篇 |
2004年 | 98篇 |
2003年 | 68篇 |
2002年 | 82篇 |
2001年 | 33篇 |
2000年 | 23篇 |
1999年 | 20篇 |
1998年 | 22篇 |
1997年 | 13篇 |
1996年 | 12篇 |
1995年 | 13篇 |
1994年 | 13篇 |
1993年 | 8篇 |
1992年 | 5篇 |
1991年 | 8篇 |
1989年 | 5篇 |
1988年 | 6篇 |
1987年 | 6篇 |
1986年 | 7篇 |
1985年 | 5篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1982年 | 9篇 |
1981年 | 7篇 |
1980年 | 9篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1976年 | 8篇 |
1975年 | 10篇 |
1974年 | 6篇 |
1973年 | 4篇 |
1970年 | 4篇 |
排序方式: 共有1787条查询结果,搜索用时 15 毫秒
41.
Virve Koljonen Markku Laitila Harri Sintonen Risto P. Roine 《Burns : journal of the International Society for Burn Injuries》2013
Objective
Health-related quality of life (HRQoL) has gained increasing interest as an important indicator of adaptation after a burn injury. Our objective was to compare HRQoL of medium severity hospitalized burn victims with no need for intensive care treatment with that of the general population.Methods
The 15D HRQoL questionnaire at discharge, and 6, 12 and 24 months thereafter.Results
44 patients filled in the baseline questionnaire between June 2007 and December 2009. At discharge the mean (SD) HRQoL score (on a scale of 0–1) of the patients was worse in comparison with that of the general population (0.839 (0.125) vs. 0.936 (0.071)), p < 0.001. The most striking differences (p < 0.001) were seen on the dimensions of sleeping, usual activities, discomfort and symptoms, and sexual activity. At the 2-year follow-up the mean HRQoL score had increased from 0.835 (0.121) to 0.856 (0.149), but the difference was not statistically significant. Of the dimensions, moving and usual activities improved statistically significantly.Conclusions
HRQoL of patients hospitalized for treatment of burns is, at discharge, compromised compared with that of the general population. During follow-up HRQoL showed slight improvement but remained at a clearly lower level. 相似文献42.
Max Mazanikov Marianne Udd Leena Kylänpää Harri Mustonen Outi Lindström Jorma Halttunen Reino Pöyhiä 《Surgical endoscopy》2013,27(6):2163-2168
Background
There is a lack of studies about procedural sedation of alcoholics. Dexmedetomidine is recommended for procedural sedation and reported effective for alcohol withdrawal. We evaluated the suitability of dexmedetomidine for sedation of alcoholics during endoscopic retrograde cholangiopancreatography (ERCP).Methods
Fifty patients with chronic alcoholism scheduled for elective ERCP were randomized 1:1 to receive dexmedetomidine (Dex group) (loading dose 1 μg kg?1 over 10 min, followed by constant intravenous infusion 0.7 μg kg?1 h?1) or saline placebo (P group). Patient-controlled sedation with propofol–alfentanil was used by patients as a rescue method. Sedation was considered as successful if no intervention of an anesthesiologist was needed. Consumption of sedatives was registered, and sedation levels and vital signs were monitored.Results
Dexmedetomidine alone was insufficient in all patients. The mean ± SD consumption of propofol was 159 ± 72 mg in the P group, and 116 ± 61 mg in the Dex group (p = 0.028). Sedation was successful in 19 of 25 (76 %) patients in the Dex group and in all patients in the P group (p = 0.022). The incidence of sedation adverse events did not differ between the groups. Dexmedetomidine was associated with delayed recovery.Conclusions
Patient-controlled sedation with propofol and alfentanil but not dexmedetomidine can be recommended for sedation of alcoholics during ERCP. 相似文献43.
44.
This study assesses whether sense of coherence (SOC) predicts incidence of tooth decay over 4 years and the role of dental behaviours in explaining the effect of SOC on incidence of tooth decay. Data from 994 adults who participated in both the Health 2000 survey and the Follow-Up Study of Finnish Adults' Oral Health were analysed for this study. At baseline, participants provided information on demographic characteristics, education level, the SOC scale and dental behaviours (tooth brushing frequency, dental attendance and sugar intake frequency). The 4-year incidence of tooth decay was calculated using data from baseline and follow-up clinical oral examinations. Baseline SOC was significantly related to 4-year incidence of tooth decay after adjustment for demographic factors and education (relative risk: 0.79, 95% CI: 0.63-0.98). This effect was fully attenuated after further adjustment for the three dental behaviours. Tooth brushing frequency and dental attendance were the only dental behaviours significantly related to incidence of tooth decay. This prospective study suggests that SOC predicts incidence of tooth decay and that dental behaviours may help explaining why adults with strong SOC have lower risk of developing tooth decay than those with weak SOC. 相似文献
45.
46.
P. Jylhä M. Ketokivi O. Mantere T. Melartin K. Suominen M. Vuorilehto M. Holma I. Holma E. Isometsä 《European psychiatry》2013,28(8):483-491
ObjectiveTo study, whether temperament and character remain stable over time and whether they differ between patients with and without personality disorder (PD) and between patients with specific PDs.MethodsPatients with (n = 225) or without (n = 285) PD from Jorvi Bipolar Study, Vantaa Depression Study (VDS) and Vantaa Primary Care Depression Study were interviewed at baseline and at 18 months, and in the VDS also at 5 years. A general population comparison group (n = 264) was surveyed by mail.ResultsCompared with non-PD patients, PD patients scored lower on self-directedness and cooperativeness. Cluster B and C PDs associated with high Novelty Seeking and Harm Avoidance, respectively. In logistic regression models, sensitivity and specificity of Temperament and Character Inventory (TCI) dimensions for presence of any PD were 53% and 75%, and for specific PDs from 11% to 41% and from 92% to 100%, respectively. The 18-month test-retest correlations of TCI-R dimensions ranged from 0.58 to 0.82.ConclusionsMedium-term temporal stability of TCI in a clinical population appears good. Character scores differ markedly between PD and non-PD patients, whereas temperament scores differ only somewhat between the specific PDs. However, the TCI dimensions capture only a portion of the differences between PD and non-PD patients. 相似文献
47.
48.
49.
Patient‐specific pharmacokinetic parameter estimation on dynamic contrast‐enhanced MRI of prostate: Preliminary evaluation of a novel AIF‐free estimation method 下载免费PDF全文