全文获取类型
收费全文 | 2176篇 |
免费 | 134篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 66篇 |
儿科学 | 58篇 |
妇产科学 | 73篇 |
基础医学 | 223篇 |
口腔科学 | 77篇 |
临床医学 | 208篇 |
内科学 | 386篇 |
皮肤病学 | 69篇 |
神经病学 | 134篇 |
特种医学 | 70篇 |
外科学 | 332篇 |
综合类 | 45篇 |
预防医学 | 144篇 |
眼科学 | 71篇 |
药学 | 219篇 |
中国医学 | 40篇 |
肿瘤学 | 112篇 |
出版年
2024年 | 4篇 |
2023年 | 36篇 |
2022年 | 83篇 |
2021年 | 110篇 |
2020年 | 87篇 |
2019年 | 97篇 |
2018年 | 104篇 |
2017年 | 89篇 |
2016年 | 68篇 |
2015年 | 80篇 |
2014年 | 98篇 |
2013年 | 110篇 |
2012年 | 174篇 |
2011年 | 145篇 |
2010年 | 93篇 |
2009年 | 71篇 |
2008年 | 150篇 |
2007年 | 109篇 |
2006年 | 111篇 |
2005年 | 84篇 |
2004年 | 68篇 |
2003年 | 69篇 |
2002年 | 59篇 |
2001年 | 32篇 |
2000年 | 19篇 |
1999年 | 21篇 |
1998年 | 15篇 |
1997年 | 9篇 |
1996年 | 5篇 |
1995年 | 8篇 |
1994年 | 5篇 |
1993年 | 3篇 |
1992年 | 10篇 |
1991年 | 7篇 |
1990年 | 13篇 |
1989年 | 11篇 |
1988年 | 10篇 |
1987年 | 10篇 |
1986年 | 5篇 |
1985年 | 8篇 |
1984年 | 8篇 |
1983年 | 3篇 |
1982年 | 3篇 |
1981年 | 5篇 |
1978年 | 3篇 |
1977年 | 4篇 |
1976年 | 3篇 |
1975年 | 3篇 |
1969年 | 2篇 |
1928年 | 1篇 |
排序方式: 共有2327条查询结果,搜索用时 15 毫秒
21.
22.
Bs. Titi Haerana Nurhayati Adnan Prihartono Pandu Riono Ratna Djuwita Syahrizal Syarif Ella Nurlaella Hadi Nastiti Kaswandani 《The Indian journal of tuberculosis》2021,68(3):350-355
BackgroundChildren who inhabit the same house with tuberculosis (TB) patients are at high risk for infection and illness with TB. Nutritional status (stunting) in children is related to the child's ability to withstand MTB (Mycobacterium Tuberculosis). This study aims to estimated the prevalence of tuberculosis infection and its relationship to stunting in children (under five years) with household contact (HHC) with new TB cases.MethodsA cross-sectional design was implemented. Conducted in July 2018–April 2019 at 13 Public Health Center in Makassar City. The sample size was calculated using one sample situation-about precision formula. Samples were children under five who had contact with new diagnosed TB cases. Tuberculosis infection was measured by TST (tuberculin skin test). Logistic regression with causal model to examine TB infection relationship with stunting and covariate variable, analyzed using Stata/MP 13.0 software.ResultsOne hundred twenty-six (126) eligible children. Prevalence of tuberculosis infection was 38.10%. Frequency of stunted was 31 children (24.60%). Stunted nutritional status (aPR): 2.36, 95% CI 1.60–3.44), boys (aPR: 1.47, 95% CI 0.96–2.25), not getting BCG immunization (aPR: 1.58, 95%) CI 0.89–2.82), and high contact intensity (aPR: 2.62, 95% CI 1.10–6.22) best predicted the tuberculosis infection in children with TB case household contacts with a model contribution of 64%.ConclusionStunted nutritional status (moderate and severe), boys, not getting BCG immunization, and high contact intensity are the determinants of TB infection transmission in children HHC with TB. Children under five years of age who have close contact with TB cases should be targeted for priority interventions to prevent the transmission of TB infection and progressing to TB cases. 相似文献
23.
Hassan Malekinejad Soheyl Varasteh Fatemeh Rahmani Hadi Cheraghi Arash Alizadeh Mehdi Behfar 《Toxin reviews》2015,34(2):101-108
This study was conducted to clarify the role of efflux transporter MRP2 in acetaminophen-induced hepatotoxicity in cats. Sixteen mixed bred male cats and four liver samples from mixed breed male dogs were used. The cats were assigned into four groups (n?=?4), received saline and 2, 10 and 50?mg/kg doses of acetaminophen orally for 14 days. Unlike the intact dogs, the MRP2 was not detectable in control cats. MRP2 at mRNA level was expressed in the liver of cats, which received the medium and high doses. Data suggest that the MRP2 expression may involve in the acetaminophen-induced hepatotoxicity in cats. 相似文献
24.
Kılavuz Sebile Basaranoglu Murat Epcacan Serdar Bako Derya Ozer Arife Donmez Yasemin Nuran Ceylan Emine Ipek Tukun Ajlan Ceylaner Serdar Geylani Hadi Mungan Halise Neslihan Onenli 《Metabolic brain disease》2022,37(4):1283-1287
Metabolic Brain Disease - Gaucher disease type 2 is the most progressive and the rarest form of Gaucher disease, defined as the acute neuronopathic type. We presented two GD2 patients who died... 相似文献
25.
Gregoric ID Cohn WE Akay MH La Francesca S Myers T Frazier OH 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2008,35(2):184-185
The CentriMag left ventricular assist system can be used for perioperative or postcardiotomy circulatory support of the failing heart. The device resides at the patient's bedside, and the cannulae are usually inserted through a midline sternotomy, with the inflow cannula in the left ventricle or right superior pulmonary vein and the outflow cannula in the aorta. In a patient whose chest has been closed and who has a delayed need for temporary mechanical support, a less invasive method of left ventricular assist device cannula insertion is preferred. In these cases, the CentriMag cannulae can be inserted through a right minithoracotomy with the inflow cannula in the right superior pulmonary vein and the outflow cannula in the aorta, with no heparinization. Herein, we describe this approach in a patient who experienced postcardiotomy cardiogenic shock after aortocoronary bypass surgery. This technique may facilitate ambulation and recovery in selected patients. 相似文献
26.
Majid Nimrouzi Omid Sadeghpour Mohammad Hadi Imanieh Mohammadreza Shams Ardekani Alireza Salehi Mohamad Bagher Minaei Mohammad M. Zarshenas 《Iranian journal of pediatrics.》2015,25(2)
Background:
Polyethylene glycol (PEG) is often considered as the first-line treatment for functional constipation in children. Descurainia sophia (L.) Webb et Berth (D. sophia) is a safe recommended medicine in Iranian folk and Traditional Persian Medicine for the treatment of constipation.Objectives:
To clinically compare D. sophia with PEG 4000 (without electrolyte) in pediatric constipation and to assess its efficacy and side effects.Patients and Methods:
120 patients aged 2 - 12 years with constipation for at least 3 months were included in an 8 weeks lasting randomized controlled trial within two parallel-groups. Children received either PEG, 0.4 g/kg/day, or D. sophia seeds, 2 grams (for children aged 2 - 4 years) and 3 grams (for those aged > 4 years) per day.Results:
A total of 109 patients completed the study (56 in D. sophia and 53 in PEG group). At the end of the study, 36 (64.3%) patients in D. sophia group and 29 (54.7%) in PEG group were out of Rome III criteria (P = 0.205). Median weekly stool frequency in 0, 1, 2, 3 weeks of the treatment was found to be 2, 5, 5, 5 in D. sophia and 3, 4, 4, 5 in PEG group (P = 0.139, 0.076, 0.844, 0.294), respectively. The number of patients who suffered flatulence was less (5, 8.9%) in D. sophia group as compared to PEG group (6, 11.3%) at the end of the trial (P = 0.461). D. sophia taste was less tolerated.Conclusions:
D. sophia is introduced as a cheap and available medication which can be applied as a safe alternative to conventional PEG in the management of pediatric chronic functional constipation. 相似文献27.
Vijay Kumar Rajeev Kumar Gupta Ravi Kumar Gundampati Devendra Kumar Singh Sweta Mohan Syed Hadi Hasan Manisha Malviya 《RSC advances》2018,8(2):619
The current study aims at the development of an electrochemical sensor based on a silver nanoparticle–reduced graphene oxide–polyaniline (AgNPs–rGO–PANI) nanocomposite for the sensitive and selective detection of hydrogen peroxide (H2O2). The nanocomposite was fabricated by simple in situ synthesis of PANI at the surface of rGO sheet which was followed by stirring with AEC biosynthesized AgNPs to form a nanocomposite. The AgNPs, GO, rGO, PANI, rGO–PANI, and AgNPs–rGO–PANI nanocomposite and their interaction were studied by UV-vis, FTIR, XRD, SEM, EDX and XPS analysis. AgNPs–rGO–PANI nanocomposite was loaded (0.5 mg cm−2) on a glassy carbon electrode (GCE) where the active surface area was maintained at 0.2 cm2 for investigation of the electrochemical properties. It was found that AgNPs–rGO–PANI–GCE had high sensitivity towards the reduction of H2O2 than AgNPs–rGO which occurred at −0.4 V vs. SCE due to the presence of PANI (AgNPs have direct electronic interaction with N atom of the PANI backbone) which enhanced the rate of transfer of electron during the electrochemical reduction of H2O2. The calibration plots of H2O2 electrochemical detection was established in the range of 0.01 μM to 1000 μM (R2 = 0.99) with a detection limit of 50 nM, the response time of about 5 s at a signal-to-noise ratio (S/N = 3). The sensitivity was calculated as 14.7 μA mM−1 cm−2 which indicated a significant potential as a non-enzymatic H2O2 sensor.The current study aims at the development of an electrochemical sensor based on a silver nanoparticle–reduced graphene oxide–polyaniline (AgNPs–rGO–PANI) nanocomposite for the sensitive and selective detection of hydrogen peroxide (H2O2). 相似文献
28.
29.
Brian E. Dixon Jamie Pina Hadi Kharrazi Fardad Gharghabi Janise Richards 《Online Journal of Public Health Informatics》2015,7(2)
Objective: To categorize and describe the public health informatics (PHI) and
global health informatics (GHI) literature between 2012 and 2014.Methods: We conducted a semi-systematic review of articles published between
January 2012 and September 2014 where information and communications
technologies (ICT) was a primary subject of the study or a main component of the
study methodology. Additional inclusion and exclusion criteria were used to
filter PHI and GHI articles from the larger biomedical informatics domain.
Articles were identified using MEDLINE as well as personal bibliographies from
members of the American Medical Informatics Association PHI and GHI working
groups.Results: A total of 85 PHI articles and 282 GHI articles were identified. While
systems in PHI continue to support surveillance activities, we identified a
shift towards support for prevention, environmental health, and public health
care services. Furthermore, articles from the U.S. reveal a shift towards PHI
applications at state and local levels. GHI articles focused on telemedicine,
mHealth and eHealth applications. The development of adequate
infrastructure to support ICT remains a challenge, although we identified a
small but growing set of articles that measure the impact of ICT on clinical
outcomes.Discussion: There is evidence of growth with respect to both implementation of
information systems within the public health enterprise as well as a widening of
scope within each informatics discipline. Yet the articles also illuminate the
need for more primary research studies on what works and what does not as both
searches yielded small numbers of primary, empirical articles.Conclusion: While the body of knowledge around PHI and GHI continues to mature,
additional studies of higher quality are needed to generate the robust evidence
base needed to support continued investment in ICT by governmental health
agencies. 相似文献
30.
Eskandarifard Ebrahim Silva Rui Nobari Hadi Clemente Filipe Manuel Pérez-Gómez Jorge Figueiredo António José 《Sport Sciences for Health》2022,18(2):297-305
Sport Sciences for Health - The purposes of this study were to describe the fitness and hormonal levels according to playing time (PT) (i.e., PT during season less (PT1) or more (PT2) than 50% of... 相似文献