全文获取类型
收费全文 | 221篇 |
免费 | 12篇 |
国内免费 | 41篇 |
专业分类
儿科学 | 15篇 |
妇产科学 | 1篇 |
基础医学 | 39篇 |
口腔科学 | 8篇 |
临床医学 | 37篇 |
内科学 | 59篇 |
皮肤病学 | 3篇 |
神经病学 | 5篇 |
特种医学 | 51篇 |
外科学 | 9篇 |
综合类 | 16篇 |
预防医学 | 6篇 |
眼科学 | 2篇 |
药学 | 15篇 |
中国医学 | 1篇 |
肿瘤学 | 7篇 |
出版年
2021年 | 1篇 |
2020年 | 1篇 |
2019年 | 1篇 |
2018年 | 1篇 |
2017年 | 4篇 |
2016年 | 2篇 |
2015年 | 9篇 |
2014年 | 4篇 |
2013年 | 11篇 |
2012年 | 4篇 |
2011年 | 2篇 |
2010年 | 10篇 |
2009年 | 11篇 |
2008年 | 4篇 |
2007年 | 28篇 |
2006年 | 6篇 |
2005年 | 11篇 |
2004年 | 1篇 |
2003年 | 1篇 |
2002年 | 2篇 |
2001年 | 1篇 |
2000年 | 3篇 |
1999年 | 5篇 |
1998年 | 14篇 |
1997年 | 27篇 |
1996年 | 20篇 |
1995年 | 7篇 |
1994年 | 9篇 |
1993年 | 7篇 |
1992年 | 1篇 |
1991年 | 2篇 |
1989年 | 8篇 |
1988年 | 6篇 |
1987年 | 6篇 |
1986年 | 6篇 |
1985年 | 3篇 |
1984年 | 5篇 |
1983年 | 3篇 |
1982年 | 4篇 |
1981年 | 7篇 |
1980年 | 5篇 |
1979年 | 1篇 |
1977年 | 1篇 |
1976年 | 7篇 |
1975年 | 2篇 |
排序方式: 共有274条查询结果,搜索用时 15 毫秒
41.
42.
目的:用HPLC和电荷转移络合UV法分别测定特非那丁粒剂的含量,并对测定结果进行比较,方法:HPLC法,色谱柱:SpherisorbC8(150*4.6mm,5μm);流动相:甲醇-0.1mol/L三乙胺磷酸缓冲液(80:20),检测波长235nm。电荷转移络合UV法,利用碘与TFN在氯仿中形成电荷转移络合物的原理,在紫外294nm的波长处测定TFN的含量。结果:两法测定的线性范围和平均回收率分别 相似文献
43.
44.
45.
46.
47.
MA Islam RI Chowdhury N Chakraborty W Bari HH Akhter 《The European journal of contraception & reproductive health care》2013,18(4):203-213
Objectives There are only a few studies on maternal morbidity, delivery complications and maternal mortality in Bangladesh. This study analyzes data from a follow-up study conducted by the Bangladesh Institute of Research for Health and Technologies (BIRPERHT) on maternal morbidity in rural Bangladesh in 1993. Methods A total of 1020 pregnant women were interviewed in the follow-up component of the study. The survey collected information on socioeconomic and demographic characteristics, pregnancy-related care and practice, morbidity during the period of follow-up as well as in the past, information concerning complications at the time of delivery and during the postpartum period. For the purpose of this study, we selected 993 pregnant women with at least one antenatal follow-up. Both bivariate and multivariate analyses were conducted to identify the potential risk factors for complication during delivery and duration of labor. Results and conclusions It appears that complications during the antenatal period can result in various complications at the time of delivery. Some of the important findings are: hemorrhage during the antenatal period increases the risk of excessive hemorrhage during delivery, the risk of obstructed labor increases significantly if abdominal pain is observed during the antenatal period, prolonged labor appears to be significantly higher for the first pregnancy, and pregnancies suffering from abdominal pain during pregnancy tend to have a higher risk of prolonged labor during delivery. The duration of labor appears to be negatively associated with the number of previous pregnancies, being longest for the first pregnancies. The duration of labor pain is significantly higher for the respondents who reported the index pregnancy as undesired, and, similarly, the respondents who were reported to be involved with gainful employment would have a shorter duration of labor pain than those having no involvement with gainful employment. 相似文献
48.
Cathy CROMBIE W Ivon BURNS Christos KARAPETIS Ray M LOWENTHAL Fred KIRSTEN J Andrew DAVIDSON Fiona ABELL William HH REECE Jose IGLESIAS Paul DE SOUZA 《Asia-Pacific Journal of Clinical Oncology》2009,5(1):24-31
Aim: Two 21-day gemcitabine–carboplatin schedules were evaluated in patients with advanced non-small cell lung cancer in order to assess the effect of timing of the carboplatin dose on toxicity and efficacy.
Methods: Patients were randomized to gemcitabine (1000 mg/m2 on days 1 and 8 of a 21-day cycle) and carboplatin (AUC 5, on day 1) (Carbo d1 arm) or the same gemcitabine schedule with carboplatin given on day 8 (Carbo d8 arm). Twenty patients with Stage IIIB or IV non-small-cell lung cancer were enrolled in each arm.
Results: The achieved dose intensities of both gemcitabine and carboplatin were significantly higher in the Carbo d1 arm. The total rates of grade 3 or 4 hematological and non-hematological toxicities (any toxicity, any cycle) were 80% and 65%, respectively, with no significant differences between the two arms. Nine patients in the Carbo d1 arm, but only one patient in the Carbo d8 arm, required a platelet transfusion. There were 10 partial responses (four Carbo d1 arm, six Carbo d8 arm), giving an overall response rate of 25% (95% CI 13–41%).
Conclusion: Administration of carboplatin on day 8 of this regimen confers no clear advantage compared with day 1 carboplatin, with similar toxicity but lower dose intensity. A formula for the prediction of thrombocytopenia is proposed. 相似文献
Methods: Patients were randomized to gemcitabine (1000 mg/m
Results: The achieved dose intensities of both gemcitabine and carboplatin were significantly higher in the Carbo d1 arm. The total rates of grade 3 or 4 hematological and non-hematological toxicities (any toxicity, any cycle) were 80% and 65%, respectively, with no significant differences between the two arms. Nine patients in the Carbo d1 arm, but only one patient in the Carbo d8 arm, required a platelet transfusion. There were 10 partial responses (four Carbo d1 arm, six Carbo d8 arm), giving an overall response rate of 25% (95% CI 13–41%).
Conclusion: Administration of carboplatin on day 8 of this regimen confers no clear advantage compared with day 1 carboplatin, with similar toxicity but lower dose intensity. A formula for the prediction of thrombocytopenia is proposed. 相似文献
49.
50.
生物制剂可用于治疗各种疾病,包括肿瘤、风湿、胃肠道疾病、皮肤科疾病、呼吸道疾病、激素缺乏症和感染。尽管近来批准了很多生物制品,但有关其药物间相互作用临床研究还不多。单克隆抗体是最主要的一类治疗性生物制品,本文介绍评价其药物间相互作用的风险评估策略,指出了评估中的关键因素,并建议将相互作用风险评估作为治疗性生物制品综合药物开发的一部分。 相似文献