全文获取类型
收费全文 | 2013篇 |
免费 | 118篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 52篇 |
妇产科学 | 33篇 |
基础医学 | 213篇 |
口腔科学 | 30篇 |
临床医学 | 189篇 |
内科学 | 335篇 |
皮肤病学 | 16篇 |
神经病学 | 220篇 |
特种医学 | 120篇 |
外科学 | 290篇 |
综合类 | 56篇 |
一般理论 | 1篇 |
预防医学 | 243篇 |
眼科学 | 15篇 |
药学 | 128篇 |
中国医学 | 21篇 |
肿瘤学 | 164篇 |
出版年
2022年 | 9篇 |
2021年 | 17篇 |
2020年 | 18篇 |
2019年 | 27篇 |
2018年 | 33篇 |
2017年 | 25篇 |
2016年 | 21篇 |
2015年 | 29篇 |
2014年 | 42篇 |
2013年 | 88篇 |
2012年 | 89篇 |
2011年 | 85篇 |
2010年 | 73篇 |
2009年 | 63篇 |
2008年 | 79篇 |
2007年 | 85篇 |
2006年 | 106篇 |
2005年 | 84篇 |
2004年 | 102篇 |
2003年 | 75篇 |
2002年 | 58篇 |
2001年 | 51篇 |
2000年 | 64篇 |
1999年 | 46篇 |
1998年 | 38篇 |
1997年 | 35篇 |
1996年 | 36篇 |
1995年 | 41篇 |
1994年 | 24篇 |
1993年 | 20篇 |
1992年 | 45篇 |
1991年 | 32篇 |
1990年 | 30篇 |
1989年 | 60篇 |
1988年 | 29篇 |
1987年 | 46篇 |
1986年 | 40篇 |
1985年 | 31篇 |
1984年 | 37篇 |
1983年 | 22篇 |
1982年 | 17篇 |
1981年 | 17篇 |
1980年 | 15篇 |
1979年 | 16篇 |
1978年 | 16篇 |
1977年 | 13篇 |
1976年 | 11篇 |
1975年 | 16篇 |
1974年 | 14篇 |
1973年 | 10篇 |
排序方式: 共有2137条查询结果,搜索用时 15 毫秒
71.
R Gustafson 《Drug and alcohol dependence》1988,21(3):237-242
Twenty subjects participated in an experiment testing the effects of a moderate dose of beer on physical aggression. Subjects were randomly assigned to a beer drinking group or a control group. Aggression was measured in terms of number of shocks given, shock intensity, and shock duration in a modified version of the Buss' aggression machine. There were no differences among groups and there was no interaction of beer by frustration on aggression. The results are explained in terms of expectancies held by subjects as to the effects of beer intoxication on behaviour. 相似文献
72.
73.
腺病毒载体介导的PML生长抑制因子对前列腺癌细胞生长和致瘤能力的抑制效果 总被引:1,自引:0,他引:1
为探讨用腺病毒载体携带PML(PromyelocyticLeukemia)基因作为前列腺癌基因治疗的可能性,应用重组人携带PML基因腺病毒(AdPML)感染培养的前列腺癌细胞,观察表达PML蛋白的癌细胞与对照组癌细胞的体外生长和裸鼠体内致瘤能力变化,对荷瘤裸鼠瘤体周围注射AdPML,观察治疗组和对照组肿瘤生长的变化。结果显示,感染AdPML的前列腺癌细胞体外生长和裸鼠体内致瘤能力明显下降,荷瘤裸鼠瘤体周围注射AdPML后肿瘤生长速度明显减慢。证实了PML是一种生长抑制因子,提示其可能被应用于前列腺癌的基因治疗研究 相似文献
74.
75.
Background
Despite extensive research, the five-year survival rate of oral squamous cell carcinoma (OSCC) patients has not improved. Effective treatment of OSCC requires the identification of molecular targets and signaling pathways to design appropriate therapeutic strategies. Several genes from the mTOR signaling pathway are known to be dysregulated in a wide spectrum of cancers. However, not much is known about the involvement of this pathway in tumorigenesis of OSCC. We therefore investigated the role of the tumor suppressor genes, TSC1 and TSC2, and other members of this pathway in tumorigenesis of OSCC. 相似文献76.
Schaffer MA Mather S Gustafson V 《Journal of health care for the poor and underserved》2000,11(4):385-399
An agency providing health care services for homeless persons and a nursing department at a liberal arts college established a service-learning partnership to complete a health needs assessment of homeless persons. Under the guidance of agency staff and a nursing faculty member, seven nursing students surveyed shelter residents (n = 101) in four urban shelters and conducted a focus group to identify residents' perceptions of health, health care needs, and health care service delivery. The service-learning partnership expanded the agency's services by providing research consultation and data collection that resulted in recommendations to improve health care services for the homeless. The agency contributed to the education of health professionals by providing students with a meaningful community service experience. 相似文献
77.
Office endoscopy--when, why, what, and how 总被引:4,自引:0,他引:4
Comprehensive diagnostic nasal endoscopy is a relatively recent advance in the office practice of rhinology. The examination is performed most commonly with 4.0-mm telescopes (0 and 30 degrees) and 2.7-mm telescopes (30 and 70 degrees). Nasal endoscopy provides the rhinologist with unparalleled visualization with brilliant illumination of the nasal cavity which permits more accurate diagnosis of nasal conditions. It also serves as an excellent teaching tool and source of photodocumentation. 相似文献
78.
Studies on blood viscosity during the menstrual cycle and in the postmenopausal period in healthy women 总被引:1,自引:0,他引:1
H Larsson S Persson P Hedner H Odeberg A Gustafson 《Acta obstetricia et gynecologica Scandinavica》1989,68(6):483-486
Blood viscosity was measured in 14 healthy, menstruating women, aged 17-51 years and in 10 healthy, postmenopausal women, aged 55-64 years. The fertile women were studied once a week during a normal menstrual cycle and the postmenopausal women twice with an interval of 2 weeks. Blood viscosity was measured at natural hematocrit as well as at hematocrit 45%. In the postmenopausal women no changes in blood viscosity were found. In the fertile women, blood viscosity at hematocrit 45% was lowest at the start of the menstrual bleeding and increased to a peak at day 7 (p less than 0.01), with a similar pattern when measured at natural hematocrit. Plasma viscosity also had its lowest value at the onset of menstrual bleeding, increasing to a maximum at day 21. Changes in plasma triglycerides, but not in fibrinogen or cholesterol, seemed to contribute to this increase. Plasma factors only partly explained the variations in blood viscosity, and changes in red cell properties were also found to be of importance. The clinical significance of these rheological changes remains to be established, but at least theoretically there may be an increased risk for thromboembolism, e.g. at surgery, during days 5-15 of the cycle. In studies on blood flow and rheological conditions in fertile women, it seems advisable to standardize for time in the menstrual cycle. 相似文献
79.
Auditory brainstem response (ABR) testing is a reliable and sensitive test for retrocochlear pathology in neurotologic diagnosis. Several investigators have reported the sensitivity of ABR testing as 95% or greater. Fifty-one consecutive patients with surgically confirmed acoustic neuromas were examined. Forty patients had sufficient hearing preoperatively for assessment with ABR. In addition, all had been evaluated with gadolinium-enhanced magnetic resonance imaging and conventional electronystagmography. Overall, 34 of 40 patients (85%) had abnormal ABRs. One of 25 patients with extracanalicular tumors had a normal ABR for a false-negative rate of 4%; however, 5 of 15 patients with intracanalicular tumors had normal ABRs for a false-negative rate of 33%. Tumor size and nerve of origin were important factors affecting the ABR sensitivity. The ABR was less sensitive in detecting intracanalicular tumors than in detecting extracanalicular tumors. 相似文献
80.
Effects of positive and negative pressure ventilation on cerebral blood volume of newborn infants 总被引:3,自引:0,他引:3
KS Palmer SA Spencer YABD Wickramasinghe T Wright DP Southall P Rolfe 《Acta paediatrica (Oslo, Norway : 1992)》1995,84(2):132-139
The effects of intermittent positive airway and continuous negative extrathoracic pressure ventilation on cerebral blood volume in preterm infants were studied using near infrared spectroscopy. In 12 infants continuous negative extrathoracic pressure caused a median decrease in cerebral blood volume of 0.14ml/100ml brain (95% confidence intervals (CI) 0.035–0.280) compared with no respiratory support. Oxygenated and deoxygenated haemoglobin also decreased, implying increased venous drainage as the main effect. In 17 infants intermittent positive pressure ventilation also caused a median reduction in cerebral blood volume of 0.06 ml/100 ml brain (95% CI 0.010–0.115) compared with endotracheal positive airway pressure. Deoxygenated haemoglobin increased by 0.07 ml/100 ml brain (95% CI 0.010–0.100) while oxygenated haemoglobin decreased by O.lOml/lOOml brain (95% CI 0.005–0.175). The increase in deoxygenated haemoglobin implies decreased venous drainage and the decrease in oxygenated haemoglobin implies that other factors may also be significant. Heart rate, blood pressure and oxygen saturation were monitored continuously and remained stable. 相似文献