精索内静脉造影定位不能触及的隐睾(附12例报告)

本文报告精索内静脉造影定位不能触及的隐睾症12例。10例造影获得成功,其中右侧3例,左侧7例。造影及手术对照结果提示:①精索内静脉及蔓状丛显影表明有睾丸存在。②出现盲端静脉表明无睾丸存在。③长段精索内静脉显影无典型蔓状丛表明有睾丸存在。     

父母提示对儿童少年饮食行为的影响

目的 了解父母提示或强迫对城市儿童少年饮食行为的影响，为制定营养教育策略提供科学依据。方法 采用三阶段分层随机整群抽样的方法从广泛，上海，济南和哈尔滨等4个城市，随机选取学龄前儿童和中小学生家长9464名作为调查对象，使用问卷调查子总是或经常服从的比率为38．0％－44．0％；有10．1％－10．9％的父母在就餐时总是或经常强迫孩子吃某种食物，强迫后，孩子总是或经常服从的比率为28．2％－33．5％。结论 城市儿童少年父母就餐时对孩子的提示或强迫会影响孩子的饮食，应在家长中开展营养知识教育，使他们能够正确指导孩子的饮食。     

关于肽类生长因子对神经发育作用及其机制的认识

肽类生长因子对神经系统发育发挥着重要的调控作用，与神经退行性疾病的发生和发展也密切相关，在研究过程中要运用哲学原理作指导，充分认识肽类生长因子结构和功能的多样性、其受体及其作用机制的复杂性，处理好基础研究与实践的辨证关系，从单纯分析研究走向系统研究。     

肾移植术后并发泌尿系统肿瘤的相关因素与临床干预

目的:探讨肾移植术后并发泌尿系统肿瘤的相关因素与临床干预措施.方法:报告9例(10次)此种患者的临床资料.9例肾移植术后均行免疫抑制治疗.肿瘤均发生在自体肾、输尿管和膀胱:肾透明细胞癌、肾肉瘤和膀胱腺癌各1例,肾盂输尿管膀胱移行细胞癌6例,其中1例先发生膀胱腺癌后又发生肾盂输尿管移行细胞癌.肿瘤发生于移植术后8～146个月,且8例发生在应用新型免疫抑制剂之后.患者均有服用龙胆泻肝丸或冠心苏合丸史.8例接受了根治性手术,1例未能手术切除.结果:9例随访8～44个月,未能手术切除1例于术后5个月肝转移死亡.1例肉瘤复发后放弃治疗后死亡.1例膀胱肿瘤复发,行膀胱全切腹壁造瘘术,1例腺癌已出现肺和胸膜转移.另5例最后随访时存活良好.结论:肾移植术后并发泌尿系统肿瘤以移行细胞癌为多;可能与服用含马兜铃的中药和应用新型免疫抑制剂有关;根治性手术治疗、减少免疫抑制剂用量和更换免疫抑制剂种类是主要临床干预措施.     

三步正骨手法整复尺桡骨中下段双骨折的多中心临床研究

目的：比较观察三步正骨手法整复及髓内针内固定治疗尺桡骨中下段双骨折的疗效。方法：随机分实验组105例和对照组105例，实验组接受拔伸旋转、夹挤分离和折顶回旋三步正骨手法复位加小夹板外固定，对照组接受手术开放复位，髓内针内固定治疗。结果：随访6个月，骨折解剖对位及近解剖对位情况，对照组优于实验组；骨折愈合及功能恢复情况，实验组均优于对照组。结论：应用三步正骨手法整复尺桡骨中下段双骨折，有利于伤肢功能恢复并能减少骨折延迟愈合、不愈合的发生。     

降脂减肥茶长期毒性实验研究

目的:观察降脂减肥茶的长期毒性。方法:降脂减肥茶高、中、低剂量组按7g/kg、3.2g/kg、1.5g/kg给SD大鼠灌胃,分别相当于临床用量的100倍、50倍、20倍。给药6周、12周和停药3周后,观察大鼠的行为活动、食欲、二便、体重、血液学和血液生化学指标,以及主要脏器系数和病理组织学检查。结果:3个给药组分别与对照组比较,各项指标差异无显著性意义。结论:本品在临床推荐的用药剂量下有一定的安全性。     

肾癌组织中微血管密度检测及其临床意义

目的探讨肾癌微血管密度(MVD)与其组织学类型、肿瘤分级及转移之间的关系;评价MVD对肾癌预后估价的意义.方法应用Ⅷ因子相关抗原(FⅧ-RAg)单克隆抗体进行免疫组化SABC法染色,检测49例原发性肾癌根治性切除术标本中MVD.结果的例肾癌组织中平均MVD为58.62±23.86,明显高于正常肾组织(P＜0.01).MVD与其局部淋巴结转移无相关性(P＞0.05),而与肾癌的分级及远处转移呈正相关(P＜0.01),与5 a生存期呈负相关(P＜0.01).结论肾癌组织中MVD与其组织学类型、肿瘤分级、远处转移及生存期均密切相关,检测肿瘤组织中MVD可作为估价肾癌预后的一项重要指标.     

Technical and Dosimetric Considerations in Multi-Isocenter Intensity Modulated Radiotherapy for Nasopharyngeal carcinoma with Small Multileaf Collimator

Multileaf collimator (MLC)-assisted intensity modulated radiotherapy (IMRT) has greatly improved the target coverage and avoidance of organs at risk (OAR) for the treatment of nasopharyngeal carcinoma; however, its implementation is also constrained by the features of the MLC. Nasopharyngeal carcinoma tends to have a large gross target volume (GTV) and clinical target volume (CTV) due to its biological characteristics. More than one isocenter may be needed when small MLCs (i.e., BrainLAB M3, whose largest field is 10 × 10 cm²) are used to treat the nasopharyngeal carcinoma. The BrainLAB IMRT system was used to evaluate the effectiveness of a multi-isocenter IMRT plan for treating nasopharyngeal cancers. Dose coverage of GTVs and CTVs were compared among IMRT plans with 1, 2 and 3 isocenters, as were dose objectives for OARs including brainstem, cord, and parotids. The dosimetric variation and the delivery time were also measured with a phantom. IMRT plans with more than 1 isocenter achieved a better dose coverage, homogeneity, and conformity on GTVs and CTVs; however, with risk of higher doses given to OARs. In most cases, one can generate satisfactory IMRT plans using the 2-isocenter IMRT planning strategy. Two-isocenter planning strategy may be a suitable compromise when more isocenters are needed.     

THE PRELIMINARY RESULTS OF TREATMENT OFADVANCED AND RECURRENT MALIGNANT LYMPHOMA BY BEAC REGIMEN SUPPORTED WITH AUTOLOGOUS HEMATOPOIETIC STEM CELLS TRANSPLANTATION

High dose chemotherapy with autologous hematopoietic stem cells transplantation (AHSCT) developed dramatically in the past decade, and great achievement has been made in the treatment of chemosensitive solid tumors, malignant lymphoma, multiple myeloma, and pediatric solid tumors. So far, high dose chemotherapy with autologous hematopoietic stem-cell support has been proposed as a potentially curative treatment for patients with recurrent, aggressive lymphoma that remains sensitive to further…