准分子激光屈光性角膜切削术治疗近视及近视散光临床分析

目的评价准分子激光屈光性角膜切削术治疗近视及近视散光的临床效果。方法应用准分子激光（NIDEKEC—5000型）治疗24D以下．伴或不件5D以内散光的近视眼。214只治疗眼随诊6个月以上。结果随诊1年以上的病例显示术后3个月屈光度及视力基本稳定。术后6个月时，在等值球镜度低于6D的治疗眼中，裸眼视力≥1．0者占92．04％，≥0．5为100％，80．53％的裸眼视力≥术前最佳矫正视力，99．12％的眼屈光度在预定矫正度数的±1．00D以内。低于10D的高度近视眼也有近似的疗效。214只治疗眼中操眼视力≥1．0者占78．97％，≥0．5为90．65％，72．43％的裸眼视力≥术前最佳矫正视力，88．32％的眼屈光度在预定矫正度数的±1．00D以内。6只眼（2．80％）最佳矫正视力减少2行以上，有Ⅱ级以上Haze的有7眼间（3．27％）。结论准分子激光屈光性角膜切削术治疗近视及近视散光具有很高程度的精确性和安全性，在＜10D的近视眼中更显示了良好的预测性和稳定性。     

催化分光光度法测定人发中微量铁

拟定了一简单实用的测定人发中铁的催化分光光度法。在实验条件下,人发中常见的数10种微量元素均不干扰铁的测定,回收率达86～106%。     

超细α-FeOOH制备过程研究 Ⅰ.制备工艺

以制备晶形、粒度、轴比等满足高性能磁粉要求的铁黄为目标,研究了碱法超细α-FeOOH合成的工艺配方和工艺条件对粒子性能的影响,包括碱比、气量、转速、Fe(OH)_2结晶条件、熟化时间等工艺参数的影响规律。重复稳定地制备出三类超微粒α-FeOOH粒子,其粒度分别为0.18、0.28、0.39μm,分布均匀,无枝叉。     

预防性应用钙拮抗剂对缺血大鼠心肌细胞和红细胞内钙变化的影响

利用大鼠缺血模型观察预防性应用钙桔抗剂尼莫地平对大鼠缺血心肌和红细胞内钙的影响发现，缺血时大鼠心肌细胞、心肌组织和红细胞内均有钙积聚，红细胞膜钙泵活性下降；缺血前30分钟给予尼莫地平可使红细胞内钙恢复至正常水平，红细胞膜钙泵活性升高；心肌细胞和心肌组织内钙虽较缺血鼠降低，但仍高于对照组。提示：（1）缺血时细胞的钙内流可能是全身性的；（2）预防性应用尼莫地平可阻滞或减轻细胞内钙超载，同时还可保护细胞膜膜泵活性。     

妇科腹腔镜手术几种激光对兔子宫壁损伤的实验研究

为掌握妇科腹腔镜手术所应用的激光器的治疗剂量，对几种激光引起的兔子宫壁热损伤进行观察。实验研究证实：所有激光产生的损伤程度与所用的剂量呈正相关。术后４８ｈ与即刻损伤程度相比，半导体激光的损伤程度明显加深、加宽；但ＣＯ２激光和ＮｄＹＡＧ激光接触式光刀无显著变化。说明应用激光行妇科腹腔镜手术治疗时，所产生的损伤与应用的功率密度有关，为临床合理选用腹腔镜下的激光治疗提供依据     

盐酸蒽丹西酮合用地塞米松对顺铂所致家犬的止吐作用

家犬静脉注射顺铂造成呕吐模型,分别用盐酸蒽丹西酮、盐酸蒽丹西酮加地塞米松进行止吐作用的观察。0.2mg/kg盐酸蒽丹西酮仅有部分止吐作用,无论0.5mg/kg和0.2mg/kg的地塞米松均无任何止吐作用,而两者合用时,止吐作用大大增强,0.2mg/kg盐酸蒽丹西酮加0.2mg/kg地塞米松,可达到完全控制顺铂所致的恶心、呕吐。     

强化政府行为促进妇幼卫生事业发展

中山市各级政府切实加强妇幼卫生工作的领导，卫生部门主动开展工作，有关部门紧密配合，以提高人口素质为宗旨，抓重点、攻难点，始终把妇幼卫生工作的主要目标纳入各级政府社会经济发展目标管理，作为考核干部和政府工作的重要内容，使各项指标如期圆满完成。     

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.

Six human cytochrome P450s expressed in HepG2 cells using vaccinia virus cDNA-directed expression, were used to study the biotransformation of caffeine and its metabolites. CYP1A2 alone was responsible for caffeine 3-demethylation and paraxanthine 7-demethylation; in addition, 1A2 catalysed virtually all reactions related to caffeine and its metabolites. The metabolic profile of caffeine biotransformation by CYP1A2 averaged 81.5% for paraxanthine, 10.8% for theobromine and 5.4% for theophylline formation. It remained quite uniform when caffeine concentrations were varied. The most striking finding was that CYP2E1 (the ethanol-inducible form) had major influences upon caffeine metabolism: in particular, it catalysed the formation of theophylline and theobromine from caffeine. Thus, the in vivo metabolite profiling of caffeine may reveal CYP2E1 activities in addition to the previously documented activities of CYP1A2, polymorphic N-acetyltransferase and xanthine oxidase.     

A comparison of arterial and venous flaps.

The survival rate and elastic properties of the anterior abdominal skin flap in Sprague-Dawley rats were studied in three groups of animals. In group 1 where the flaps were supplied by a normal artery, arterial flaps (1A) had better survival rate and elastic properties than venous flaps (1B). In group 2, where the flaps were supplied by an artery with diminished perfusion pressure, the arterial flaps (2A) still had slightly better results than venous flaps (2B). However, in group 3 where the flaps were supplied by a vein, venous flaps (3B) had better results than arterial flaps (3A).     

健侧颈7移位治疗臂丛神经根性撕脱伤最佳时间选择的实验研究

健侧颈７移位治疗臂丛神经根性撕脱伤手术分第一阶段（健侧颈７移位到移植神经），第二阶段（移植神经另一端移植修复患侧神经），二次手术间隔多少时间才能获得最好的神经再生？选用ＳＤ大鼠及健侧颈７移位的实验模型，按二次手术间隔时间的不同（０、１、２、３、４、８、１６周）分成７组，在第二次术后１２周，进行电生理测定肌张力恢复率及组织切片的形态学观察，结果证实二次手术最佳间隔时间为４～８周．此结果可提供临床参考．