全文获取类型
收费全文 | 936篇 |
免费 | 55篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 40篇 |
妇产科学 | 5篇 |
基础医学 | 96篇 |
口腔科学 | 46篇 |
临床医学 | 79篇 |
内科学 | 184篇 |
皮肤病学 | 41篇 |
神经病学 | 30篇 |
特种医学 | 153篇 |
外国民族医学 | 1篇 |
外科学 | 125篇 |
综合类 | 39篇 |
预防医学 | 59篇 |
眼科学 | 5篇 |
药学 | 52篇 |
中国医学 | 1篇 |
肿瘤学 | 40篇 |
出版年
2021年 | 5篇 |
2020年 | 7篇 |
2019年 | 8篇 |
2018年 | 13篇 |
2017年 | 14篇 |
2016年 | 14篇 |
2015年 | 25篇 |
2014年 | 16篇 |
2013年 | 33篇 |
2012年 | 26篇 |
2011年 | 30篇 |
2010年 | 34篇 |
2009年 | 48篇 |
2008年 | 26篇 |
2007年 | 18篇 |
2006年 | 18篇 |
2005年 | 19篇 |
2004年 | 38篇 |
2003年 | 20篇 |
2002年 | 15篇 |
2001年 | 17篇 |
2000年 | 11篇 |
1999年 | 24篇 |
1998年 | 57篇 |
1997年 | 65篇 |
1996年 | 58篇 |
1995年 | 42篇 |
1994年 | 44篇 |
1993年 | 39篇 |
1992年 | 8篇 |
1991年 | 15篇 |
1990年 | 16篇 |
1989年 | 17篇 |
1988年 | 22篇 |
1987年 | 23篇 |
1986年 | 21篇 |
1985年 | 9篇 |
1984年 | 4篇 |
1983年 | 8篇 |
1982年 | 18篇 |
1981年 | 3篇 |
1980年 | 9篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1977年 | 5篇 |
1976年 | 6篇 |
1970年 | 2篇 |
1968年 | 3篇 |
1965年 | 2篇 |
1959年 | 2篇 |
排序方式: 共有1001条查询结果,搜索用时 0 毫秒
81.
Safety of intra‐arterial treatment in acute ischaemic stroke patients on oral anticoagulants. A cohort study and systematic review 下载免费PDF全文
82.
When red cells (RBCs) are treated with papain, one form of the U antigen, which we have named UPS (U papain-sensitive), is almost completely removed or denatured. A second form, UPR (U papain-resistant), remains unaltered on the treated RBCs. Tests on 42 examples of anti-U showed that two contained only anti-UPS, 19 contained only -UPR, and 21 contained separable -UPS and -UPR. In those sera containing both antibodies, anti-UPR was always the stronger of the two. These findings suggest 1) that UPS is located on the Ss sialoglycoprotein (glycophorin B) at a position distal to a papain-sensitive site or that the cleavage point is within the portion of the SGP that comprises UPS, and 2) that UPR is located between the papain-sensitive site and the RBC membrane. The UPS determinant was not denatured by neuraminidase, L-cysteine, trypsin, ficin, or alpha-chymotrypsin, and it was only partially denatured by pronase. The finding that RBCs treated with para-chloromercuribenzoic acid or para-chloromercuriphenyl sulfonic acid did not react with anti-UPR but did continue to react with anti-UPS suggests that the in situ configuration of UPR, but not UPS, is dependent on the presence of one or more disulfide bonds. RBCs of the S-s-U+(weak) phenotype were shown to carry markedly reduced amounts of both UPS and UPR. 相似文献
83.
H. C. Pape M. Grotz D. Remmers A. Dwenger R. Vaske D. Wisner H. Tscherne 《Intensive care medicine》1998,24(6):590-598
Objective: To perform a reproducible long-term (10 days) large animal model of multiple systems organ failure without necessity of a
continuous stimulus. Design: Adult female merino sheep submitted to a 5-day stimulation period followed by a 5-day observation period. Day 1: Hemorrhagic
shock was combined with a traumatic surgical insult (reamed intramedullary femoral nailing), followed by serial administrations
every 12 h for 5 days of a combination of endotoxin and zymosan activated plasma. Organ function was followed for 5 further
days. Results: Cardiac index increased significantly during the study (day 1: 491 ± 8 mm Hg; day 10: 427 ± 20, p < 0.05). Liver function was impaired and bilirubin levels increased significantly (day 1: 2.9 ± 0.3 μmol/l; day 10: 7.2 ±
0.9; p < 0.05). Creatinine clearance decreased initially (day 1: 54 ± 7 ml/min), increased to a peak on day 2 (104 ± 27), and then
deteriorated again (day 10: 53 ± 18). Conclusion: This new large animal model of trauma-induced MOF is reproducible and may be suitable for the study of new therapeutic approaches
to therapy.
Received: 15 September 1997 Accepted: 3 March 1998 相似文献
84.
85.
SR Kulkarni MS Gohel RA Bulbulia MR Whyman KR Poskitt 《Annals of the Royal College of Surgeons of England》2009,91(3):210-213
INTRODUCTION
Early carotid endarterectomy (CEA) in symptomatic patients may prevent repeat cerebral events. This study investigates the relationship between waiting time for CEA and the incidence of repeat cerebral events prior to surgery in symptomatic patients.PATIENTS AND METHODS
A prospective database of consecutive patients undergoing CEA between January 2002 and December 2006 was reviewed. Repeat event rates prior to surgery were calculated using Kaplan–Meier analysis and predictive factors identified using Cox regression analysis.RESULTS
A total of 118 patients underwent CEA for non-disabling stroke, TIA and amaurosis fugax. Repeat cerebral events occurred in 34 of 118 (29%) patients at a median 51 days (range, 2–360 days) after the first event. The estimated risk of repeat events was 2% at 7 days and 9% at 1 month after first event (Kaplan–Meier survival analysis). Age (HR 1.059; 95% CI 1.014–1.106; P = 0.009] was identified as a predictor of repeat events. Patients underwent surgery at median 97 days (range, 7–621 days) after the first event. Eleven of 60 (18%) patients waiting ≤?97 days for surgery and 23 of 58 (40%) patients waiting >?97 days had repeat events. (P = 0.011, chi-squared test).CONCLUSIONS
Delays in surgery should be reduced in order to minimise repeat cerebral events in patients with symptomatic carotid stenosis, particularly in the elderly population. 相似文献86.
Background
Hepatitis B virus (HBV) infection is an important occupational risk in health care workers (HCW). In spite of HBV vaccine availability in Armed Forces, the high prevalence of HBV infection in HCW continues to be a problem. The study was undertaken to study the HBV vaccine-compliance among HCW.Methods
A cross-sectional study was conducted at a tertiary care hospital. HCW were requested to fill up the pre set questionnaire to assess the HBV vaccination coverage.Result
Amongst 254 HCW, only 57.7% were vaccinated against HBV. The vaccine compliance was lowest among housekeeping professionals. The mean age at vaccination was high (30.5 years). Amongst the vaccine non-compliant subjects, 34.3% were above 30 years of age. 32.2% HCW completed primary vaccination after spending more than 10 years in the profession. Accessibility of HBV vaccine, knowledge and perception of HBV risk were important factors in vaccine non-compliance.Conclusion
Due to low and delayed HBV vaccine-compliance, HCW continue to be at the risk of occupational HBV. Health education highlighting occupational risk of HBV, accessibility of vaccine and mandatory vaccination of HCW is recommended to increase HBV vaccine compliance among HCW.Key Words: Health care workers, Hepatitis B virus, Occupational risk, Hepatitis B vaccine 相似文献87.
Background: Management of patients with cleft lip and palate (CLP) includes orthodontic treatment prior to bone grafting. Palatal expansion is done using slow or rapid palatal expansions (RPE). Controversy still exists regarding choice of expansion appliances used. This study was conducted to find out whether the Quad helix appliance represents a reasonable alternative to using conventional rapid maxillary expansion appliance among cleft lip and palate patients. 相似文献
88.
89.
90.
Grotz TE Mansfield AS Kottschade LA Erickson LA Otley CC Markovic SN Jakub JW 《Oncology (Williston Park, N.Y.)》2011,25(14):1340-1348
The majority of locoregional recurrences in melanoma occur in the form of intradermal or subcutaneous local or in-transit metastasis. In-transit melanoma represents contamination of the lymphatic space that, if treated, can result in long-term cure in a subset of patients. The management of in-transit metastases is challenging, since the treatments and extent of disease vary greatly based on the number, depth, location, and distribution of lesions, and on their biological behavior. A number of different treatment options exist, but there is no level 1 evidence to guide clinical decision-making. Herein we present our institutional treatment algorithm, which allows for individualization based on the patient's presentation. 相似文献