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991.
Etiology of Syncope and Unexplained Falls in Elderly Adults with Dementia: Syncope and Dementia (SYD) Study
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Andrea Ungar MD PhD Chiara Mussi MD PhD Alice Ceccofiglio MD Giuseppe Bellelli MD PhD Franco Nicosia MD Mario Bo MD Daniela Riccio MD Anna Maria Martone MD Livia Guadagno MD Gabriele Noro MD Giulia Ghidoni MD Martina Rafanelli MD Niccolò Marchionni MD Pasquale Abete MD PhD 《Journal of the American Geriatrics Society》2016,64(8):1567-1573
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Luigi Dall’Oglio Tamara Caldaro Francesca Foschia Simona Faraci Giovanni Federici di Abriola Francesca Rea Erminia Romeo Filippo Torroni Giulia Angelino Paola De Angelis 《World journal of gastrointestinal endoscopy》2016,8(4):212-219
Post-esophageal atresia anastomotic strictures and postcorrosive esophagitis are the most frequent types of cicatricial esophageal stricture. Congenital esophageal stenosis has been reported to be a rare but typical disease in children; other pediatric conditions are peptic, eosinophilic esophagitis and dystrophic recessive epidermolysis bullosa strictures. The conservative treatment of esophageal stenosis and strictures(ES) rather than surgery is a well-known strategy for children. Before planning esophageal dilation, the esophageal morphology should be assessed in detail for its length, aspect, number and level, and different conservative strategies should be chosen accordingly. Endoscopic dilators and techniques that involve different adjuvant treatment strategies have been reported and depend on the stricture’s etiology, the availability of different tools and the operator’s experience and preferences. Balloon and semirigid dilators are the most frequently used tools. No high-quality studies have reported on the differences in the efficacies and rates of complications associated with these two types of dilators. There is no consensus in the literature regarding the frequency of dilations or the diameter that should be achieved. The use of adjuvant treatments has been reported in cases of recalcitrant stenosis or strictures with evidence of dysphagic symptoms. Corticosteroids(either systemically or locally injected), the local application of mitomycin C, diathermy and laser ES sectioning have been reported. Some authors have suggested that stenting can reduce both the number of dilations and the treatment length. In many cases, this strategy is effective when either metallic or plastic stents are utilized. Treatment complications, such esophageal perforations, can be conservatively managed, considering surgery only in cases with severe pleural cavity involvement. In cases of stricture relapse,even if such relapses occur following the execution of well-conducted conservative strategies, surgical stricture resection and anastomosis or esophageal substitution are the only remaining options. 相似文献
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Venerando Rapisarda Carla Loreto Michele Malaguarnera Annalisa Ardiri Maria Proiti Giuseppe Rigano Evelise Frazzetto Maria Irene Ruggeri Giulia Malaguarnera Nicoletta Bertino Mariano Malaguarnera Vito Emanuele Catania Isidoro Di Carlo Adriana Toro Emanuele Bertino Dario Mangano Gaetano Bertino 《World journal of hepatology》2016,8(13):573-590
Hepatocellular carcinoma(HCC)is the most common type of liver cancer.The main risk factors for HCC are alcoholism,hepatitis B virus,hepatitis C virus,nonalcoholic steatohepatitis,obesity,type 2 diabetes,cirrhosis,aflatoxin,hemochromatosis,Wilson’s disease and hemophilia.Occupational exposure to chemicals is another risk factor for HCC.Often the relationship between occupational risk and HCC is unclear and the reports are fragmented and inconsistent.This review aims to summarize the current knowledge regarding the association of infective and non-infective occupational risk exposure and HCC in order to encourage further research and draw attention to this global occupational public health problem. 相似文献
996.
Giulia Cangiano MD Raffaella Nenna MD PhD Antonella Frassanito MD Melania Evangelisti MD PhD Ambra Nicolai MD Carolina Scagnolari MD PhD Alessandra Pierangeli MD PhD Guido Antonelli MD PhD Paola Papoff MD PhD Laura Petrarca MD Paolo Capocaccia MD Corrado Moretti MD Fabio Midulla MD PhD 《Pediatric pulmonology》2016,51(12):1330-1335
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Gabriele Masselli Ilaria Mastroiacovo Emidio De Marco Giulia Francione Emanuele Casciani Elisabetta Polettini Gianfranco Gualdi 《World journal of radiology》2016,8(7):668-682
Crohn’s disease affects more than 500000 individuals in the United States, and about 25% of cases are diagnosed during the pediatric period. Imaging of the bowel has undergone dramatic changes in the past two decades. The endoscopy with biopsy is generally considered the diagnostic reference standard, this combination can evaluates only the mucosa, not inflammation or fibrosis in the mucosa. Actually, the only modalities that can visualize submucosal tissues throughout the small bowel are the computed tomography (CT) enterography (CTE) with the magnetic resonance enterography (MRE). CT generally is highly utilized, but there is growing concern over ionizing radiation and cancer risk; it is a very important aspect to keep in consideration in pediatric patients. In contrast to CTE, MRE does not subject patients to ionizing radiation and can be used to detect detailed morphologic information and functional data of bowel disease, to monitor the effects of medical therapy more accurately, to detect residual active disease even in patients showing apparent clinical resolution and to guide treatment more accurately. 相似文献
998.
Giulia Berti de Marinis Stefano Novello Silvia Ferrari Isabella Barzon Irene Cortella Maria Antonietta Businaro Fabrizio Fabris Anna Maria Lombardi 《Journal of thrombosis and thrombolysis》2016,42(4):586-592
Differential diagnosis between thrombotic thrombocytopenic purpura (TTP) and other thrombotic microangiopathies (TMA) is usually difficult because of frequently overlapping clinical presentations. Severely depressed ADAMTS13 activity (<10 %) seems distinctive for TTP because of its pathogenetic role. However a long debate exists in the literature about its sensibility and specificity. Our aim was to search for clinical differences between TMA patients referred to our laboratory, comparing them for protease activity <10 versus ≥10 %. ADAMTS13 activity ≥10 % patients (n = 73) showed a higher prevalence of drug- (p = 0.005) and cancer-associated (p < 0.001) TMA. Mean platelet count and renal dysfunction prevalence was lower (p < 0.001), while neurological impairment was more frequent (p = 0.001) in the <10 % ADAMTS13 activity group (n = 109), confirming previous literature findings. When taken neurological manifestations singularly, epilepsy (p = 0.04), focal motor deficit (p < 0.001) and cranial nerve palsy (p = 0.007) were more frequent in the <10 % activity group. In our case series, a <10 % ADAMTS13 activity depicts a group of patients with clinical features similar to TTP patients. Focal motor impairment or epileptic manifestations could further address toward a TTP diagnosis. Studies about treatment efficacy and follow-up are advised to determine whether laboratory findings can guide therapeutic decisions. 相似文献
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Cantarini Luca Vitale Antonio Bersani Giulia Nieves Laura Martin Cattalini Marco Lopalco Giuseppe Caso Francesco Costa Luisa Iannone Florenzo Lapadula Giovanni Galeazzi Mauro Ceribelli Angela Brunetta Enrico Selmi Carlo Rigante Donato 《Clinical rheumatology》2016,35(2):501-505
Clinical Rheumatology - The pediatric syndrome characterized by periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) and adult Behçet’s disease share some... 相似文献