首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   3187542篇
  免费   283798篇
  国内免费   13975篇
耳鼻咽喉   44493篇
儿科学   100694篇
妇产科学   82418篇
基础医学   508407篇
口腔科学   86645篇
临床医学   291710篇
内科学   563019篇
皮肤病学   87650篇
神经病学   277029篇
特种医学   126393篇
外国民族医学   361篇
外科学   503795篇
综合类   96756篇
现状与发展   58篇
一般理论   2172篇
预防医学   268631篇
眼科学   72666篇
药学   214801篇
  22篇
中国医学   9202篇
肿瘤学   148393篇
  2021年   55411篇
  2020年   36919篇
  2019年   58393篇
  2018年   73152篇
  2017年   56898篇
  2016年   62537篇
  2015年   76812篇
  2014年   111626篇
  2013年   177042篇
  2012年   85353篇
  2011年   84309篇
  2010年   116898篇
  2009年   123077篇
  2008年   72183篇
  2007年   73714篇
  2006年   85125篇
  2005年   80716篇
  2004年   82347篇
  2003年   73751篇
  2002年   63748篇
  2001年   89909篇
  2000年   82228篇
  1999年   85582篇
  1998年   64302篇
  1997年   62444篇
  1996年   60084篇
  1995年   55397篇
  1994年   49411篇
  1993年   46212篇
  1992年   58839篇
  1991年   55486篇
  1990年   52645篇
  1989年   51965篇
  1988年   48482篇
  1987年   47391篇
  1986年   45429篇
  1985年   45592篇
  1984年   43170篇
  1983年   39990篇
  1982年   39882篇
  1981年   37627篇
  1980年   35579篇
  1979年   35130篇
  1978年   32191篇
  1977年   29734篇
  1976年   27311篇
  1975年   25822篇
  1974年   26313篇
  1973年   25164篇
  1972年   23685篇
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
81.
Journal of Neuro-Oncology - Adjuvant radiation is often used in patients with low grade gliomas with high-risk characteristics with a recommended dose of 45–54 Gy. We used the...  相似文献   
82.
Maternal and Child Health Journal - Early life exposures can have an impact on a child’s developmental trajectory and children born late preterm (34–36 weeks gestational age)...  相似文献   
83.
84.
85.
Troppmair  Teresa  Egger  J.  Krösbacher  A.  Zanvettor  A.  Schinnerl  A.  Neumayr  A.  Baubin  M. 《Der Anaesthesist》2022,71(4):272-280
Die Anaesthesiologie - Die Qualität eines Rettungssystems zeichnet sich auch durch den effizienten Einsatz seiner personellen und Fahrzeugressourcen aus. So können im berechtigten Fall...  相似文献   
86.
87.
Cutaneous leiomyomas are rare benign smooth‐muscle tumors. These lesions are distinguished based on their cell of origin and are subclassified as pilar leiomyoma, angioleiomyoma, and genital‐type leiomyoma. Nipple leiomyoma is the least common genital‐type leiomyoma, arising from the dartoic muscle cell of the nipple. Histologic examination of the lesion is necessary for definitive diagnosis, and these uncommon tumors can pose a diagnostic challenge. We describe herein a series of six nipple leiomyomas with a spectrum of histologic appearances.  相似文献   
88.
Introduction: The Hedgehog (HH) pathway constitutes a collection of signaling molecules which critically influence embryogenesis. In adults, however, the HH pathway remains integral to the proliferation, maintenance, and apoptosis of adult stem cells including hematopoietic stem cells.

Areas covered: We discuss the current understanding of the HH pathway as it relates to normal hematopoiesis, the pathology of acute myeloid leukemia (AML), the rationale for and data from combination therapies including HH pathway inhibitors, and ultimately the prospects that might offer promise in targeting this pathway in AML.

Expert opinion: Efforts to target the HH pathway have been focused on impeding this disposition and restoring chemosensitivity to conventional myeloid neoplasm therapies. The year 2018 saw the first approval of a HH pathway inhibitor (glasdegib) for AML, though for an older population and in combination with an uncommonly-used therapy. Several other clinical trials with agents targeting modulators of HH signaling in AML and MDS are underway. Further study and understanding of the interplay between the numerous aspects of HH signaling and how it relates to the augmented survival of AML will provide a more reliable substrate for therapeutic strategies in patients with this poor-risk disease.  相似文献   

89.
Despite orientation and mobility (O&M) being a significant factor determining quality of life of people with low vision or blindness, there are no gold standard measures or agreement on how to measure O&M performance. In the first part of this systematic review, an inventory of O&M outcome measures used by recent studies to assess the performance of orientation and/or mobility of adults with vision impairment (low vision and blindness) is presented. A wide variety of O&M outcome measures have been implemented in different fields of study, such as epidemiologic research and interventional studies evaluating training, assistive technology, vision rehabilitation and vision restoration. The most frequent aspect of outcome measures is efficiency such as time, distance, speed and percentage of preferred walking speed, followed by obstacle contacts and avoidance, and dis/orientation and veering. Other less commonly used aspects are target identification, safety and social interaction and self-reported outcome measures. Some studies employ sophisticated equipment to capture and analyse O&M performance in a laboratory setting, while others carry out their assessment in real-world indoor or outdoor environments. In the second part of this review, the appropriateness of implementing the identified outcome measures to assess O&M performance in clinical and functional O&M practice is evaluated. Nearly a half of these outcome measures meet all four criteria of face validity (either clinical or functional), responsiveness, reliability and feasibility and have the potential to be implemented in clinical or functional O&M practice. The findings of this review confirm the complicated and dynamic nature of O&M. Multiple measures are required in any evaluation of O&M performance to facilitate holistic assessment of O&M abilities and limitations of each individual.  相似文献   
90.
Introduction: Percutaneous renal mass biopsy has evolved over the last decade with improvements on previous pitfalls including low tissue yield, high non-diagnostic rates, and complications. As understanding of tumor biology and natural history of renal cortical neoplasms has improved, percutaneous renal mass biopsy is poised to have an expanding role in an area characterized by individualized management and refined risk stratification.

Areas covered: This review summarizes the evolution of renal mass biopsy to its current state with respect to outcomes, indications, and clinical guidelines.

Expert opinion: With improved understanding of differential biological potential of renal cortical neoplasms combined with technical improvements in diagnostic yield and accuracy, utilization of renal mass biopsy is becoming an important adjunct to patient care in a broad range of clinical scenarios, including active surveillance, thermal ablation, and use of primary systemic therapy in localized and advanced settings.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号