全文获取类型
收费全文 | 2239篇 |
免费 | 280篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 45篇 |
儿科学 | 68篇 |
妇产科学 | 21篇 |
基础医学 | 235篇 |
口腔科学 | 175篇 |
临床医学 | 329篇 |
内科学 | 489篇 |
皮肤病学 | 45篇 |
神经病学 | 180篇 |
特种医学 | 34篇 |
外科学 | 284篇 |
综合类 | 25篇 |
一般理论 | 1篇 |
预防医学 | 278篇 |
眼科学 | 22篇 |
药学 | 137篇 |
肿瘤学 | 156篇 |
出版年
2024年 | 3篇 |
2023年 | 49篇 |
2022年 | 22篇 |
2021年 | 43篇 |
2020年 | 44篇 |
2019年 | 45篇 |
2018年 | 77篇 |
2017年 | 70篇 |
2016年 | 64篇 |
2015年 | 74篇 |
2014年 | 115篇 |
2013年 | 131篇 |
2012年 | 152篇 |
2011年 | 164篇 |
2010年 | 109篇 |
2009年 | 107篇 |
2008年 | 116篇 |
2007年 | 171篇 |
2006年 | 121篇 |
2005年 | 130篇 |
2004年 | 148篇 |
2003年 | 137篇 |
2002年 | 123篇 |
2001年 | 17篇 |
2000年 | 15篇 |
1999年 | 24篇 |
1998年 | 35篇 |
1997年 | 34篇 |
1996年 | 24篇 |
1995年 | 23篇 |
1994年 | 16篇 |
1993年 | 16篇 |
1992年 | 12篇 |
1991年 | 6篇 |
1990年 | 7篇 |
1989年 | 6篇 |
1988年 | 5篇 |
1987年 | 8篇 |
1985年 | 6篇 |
1984年 | 7篇 |
1983年 | 4篇 |
1982年 | 8篇 |
1981年 | 3篇 |
1980年 | 7篇 |
1979年 | 3篇 |
1977年 | 2篇 |
1976年 | 6篇 |
1966年 | 3篇 |
1960年 | 2篇 |
1936年 | 2篇 |
排序方式: 共有2524条查询结果,搜索用时 875 毫秒
101.
Eyitayo O. Owolabi RN PhD Samukelisiwe Nyamathe MBChB Conran Joseph PhD Lee-Ann Jacobs-Nzuzi Khuabi PhD Rene G. English MBChB MMed FCPHM PhD Adriaan Vlok MBChB FC MMed PhD Elaine Erasmus FCEM MMed EM DipPEC MBChB Heike I. Geduld MBChB FCEM MMed Hendrick J. Lategan BSc MBBCh MMed FCEM Kathryn M. Chu MD MPH FACS FASCRS 《Journal of evaluation in clinical practice》2023,29(2):380-391
102.
Christopher Sainsbury MD Jingya Wang PhD Krishna Gokhale MSc Dionisio Acosta-Mena PhD Samir Dhalla MRPharmS Nathan Byne Joht Singh Chandan PhD Astha Anand BMBCh Jennifer Cooper MBBCh Kelvin Okoth MPH Anuradhaa Subramanian MSc Mansoor N. Bangash PhD Thomas Taverner PhD Wasim Hanif PhD Sandip Ghosh FRCP Parth Narendran PhD Kar K. Cheng PhD Tom Marshall PhD Georgios Gkoutos PhD Konstantinos Toulis PhD Neil Thomas PhD Abd Tahrani PhD Nicola J. Adderley PhD Shamil Haroon PhD Krishnarajah Nirantharakumar MD 《Diabetes, obesity & metabolism》2021,23(1):263-269
103.
104.
Joseph L. Gerry Lewis C. Becker John T. Flaherty Myron L. Weisfeldt 《The American journal of cardiology》1980,45(1):58-62
Although thallium-201 is known to redistribute slowly into regions of ischemic myocardium after restoration of blood flow, it is not clear to what extent normalization of flow is an essential requirement for the redistribution process. In a search for a flow-independent component of thallium redistribution, 12 dogs with stenosis of the circumflex coronary artery underwent atrial pacing for either 20 minutes (group I, 6 dogs) or 2 hours (group II, 6 dogs). Radioactive thallium and radioactive microspheres, 7 to 10 μ, were injected after 10 minutes of atrial pacing in both groups. Pacing resulted in a 40 percent reduction in subendocardial blood flow to the circumflex-perfused myocardium in both groups I and II. This relative reduction in flow was maintained at a stable level over the 2 hour pacing period in group II. Thallium activity in the relatively ischemic zone was significantly greater in dogs with 2 hours of pacing (group II) than in those with 10 minutes of pacing (group I). Redistribution of thallium occurred despite the continued presence of reduced flow in circumflex-perfused endocardial tissue. These data suggest that a significant component of thallium redistribution may be flow-independent. 相似文献
105.
Denise Vijt Maria Jos Castro Gerry Endall Elizabeth Lindley Monique Elseviers 《Journal of Renal Care》2004,30(2):91-96
The first part of this report, which looked at centre policy, showed that there was no consensus on the best way to manage a patient in the rest period between PD catheter insertion and the first use of the catheter for dialysis. This paper intends to investigate if the differences in policy had any effect on complication rate and individual patient outcomes. Data were included from 298 patients of 49 participating centres. The results revealed a high rate of catheter related complications, with half of the patients having been treated for complications including leakage (29%), malfunction (23%) or infection (10%), and a quarter of patients having been hospitalised for catheter problems. Leakage was more frequently observed in lean and obese patients and if the catheter was only immobilized for a short time period. Diabetes, having constipation at first use and having rested for less than 6 hours after catheter insertion were significant risk factors for malfunction. Infection seemed to be related to the type of catheter used and hygienic precautions (not significant) and showed a significant relationship with the frequency of dressing changes. There is still an important lack of evidence on which to develop an optimal protocol for PD catheter insertion and care before first use. 相似文献
106.
Functional association between Wwox tumor suppressor protein and p73, a p53 homolog 总被引:15,自引:0,他引:15
下载免费PDF全文
![点击此处可从《Proceedings of the National Academy of Sciences of the United States of America》网站下载免费的PDF全文](/ch/ext_images/free.gif)
107.
Epidemiology and outcomes of ventilator-associated pneumonia in a large US database 总被引:52,自引:0,他引:52
Rello J Ollendorf DA Oster G Vera-Llonch M Bellm L Redman R Kollef MH;VAP Outcomes Scientific Advisory Group 《Chest》2002,122(6):2115-2121
OBJECTIVES: To evaluate risk factors for ventilator-associated pneumonia (VAP), as well as its influence on in-hospital mortality, resource utilization, and hospital charges. DESIGN: Retrospective matched cohort study using data from a large US inpatient database. PATIENTS: Patients admitted to an ICU between January 1998 and June 1999 who received mechanical ventilation for > 24 h. MEASUREMENTS: Risk factors for VAP were examined using crude and adjusted odds ratios (AORs). Cases of VAP were matched on duration of mechanical ventilation, severity of illness on admission (predicted mortality), type of admission (medical, surgical, trauma), and age with up to three control subjects. Mortality, resource utilization, and billed hospital charges were then compared between cases and control subjects. RESULTS: Of the 9,080 patients meeting study entry criteria, VAP developed in 842 patients (9.3%). The mean interval between intubation, admission to the ICU, hospital admission, and the identification of VAP was 3.3 days, 4.5 days, and 5.4 days, respectively. Identified independent risk factors for the development of VAP were male gender, trauma admission, and intermediate deciles of underlying illness severity (on admission) [AOR, 1.58, 1.75, and 1.47 to 1.70, respectively]. Patients with VAP were matched with 2,243 control subjects without VAP. Hospital mortality did not differ significantly between cases and matched control subjects (30.5% vs 30.4%, p = 0.713). Nevertheless, patients with VAP had a significantly longer duration of mechanical ventilation (14.3 +/- 15.5 days vs 4.7 +/- 7.0 days, p < 0.001), ICU stay (11.7 +/- 11.0 days vs 5.6 +/- 6.1 days, p < 0.001), and hospital stay (25.5 +/- 22.8 days vs 14.0 +/- 14.6 days, p < 0.001). Development of VAP was also associated with an increase of > $40,000 USD in mean hospital charges per patient ($104,983 USD +/- $91,080 USD vs $63,689 USD+/- $75,030 USD, p < 0.001). CONCLUSIONS: This retrospective matched cohort study, the largest of its kind, demonstrates that VAP is a common nosocomial infection that is associated with poor clinical and economic outcomes. While strategies to prevent the occurrence of VAP may not reduce mortality, they may yield other important benefits to patients, their families, and hospital systems. 相似文献
108.
Neil Swanson Martin Goddard Gerry McCann G André Ng 《Europace : European pacing, arrhythmias, and cardiac electrophysiology》2007,9(2):134-136
We describe a case report of a 49-year-old man admitted to a cardiology unit with a series of arrhythmias with no initially obvious aetiology. Further assessment and the use of cardiac magnetic resonance imaging and histology allowed a diagnosis of cardiac sarcoidosis to be made. Cardiac sarcoidosis is a major cause of death in patients with systemic sarcoidosis. Cardiac magnetic resonance imaging is an additional diagnostic tool for this condition without ionizing radiation exposure. 相似文献
109.
110.
Elizabeth J. Baker Nancy A. Beck Ellen L. Berg Helene D. Clayton-Jeter P. Charukeshi Chandrasekera J. Lowry Curley Bruce A. Donzanti Lorna C. Ewart Jane M. Gunther J. Gerry Kenna Edward L. LeCluyse Michael N. Liebman Catherine L. Pugh Paul B. Watkins Kristie M. Sullivan 《Drug discovery today》2019,24(2):624-628