全文获取类型
收费全文 | 9913篇 |
免费 | 639篇 |
国内免费 | 51篇 |
专业分类
耳鼻咽喉 | 88篇 |
儿科学 | 241篇 |
妇产科学 | 252篇 |
基础医学 | 1355篇 |
口腔科学 | 210篇 |
临床医学 | 1011篇 |
内科学 | 2337篇 |
皮肤病学 | 135篇 |
神经病学 | 825篇 |
特种医学 | 313篇 |
外科学 | 1277篇 |
综合类 | 198篇 |
一般理论 | 13篇 |
预防医学 | 809篇 |
眼科学 | 191篇 |
药学 | 732篇 |
中国医学 | 5篇 |
肿瘤学 | 611篇 |
出版年
2023年 | 57篇 |
2022年 | 84篇 |
2021年 | 190篇 |
2020年 | 147篇 |
2019年 | 174篇 |
2018年 | 193篇 |
2017年 | 160篇 |
2016年 | 127篇 |
2015年 | 223篇 |
2014年 | 297篇 |
2013年 | 459篇 |
2012年 | 714篇 |
2011年 | 715篇 |
2010年 | 381篇 |
2009年 | 324篇 |
2008年 | 592篇 |
2007年 | 670篇 |
2006年 | 654篇 |
2005年 | 624篇 |
2004年 | 599篇 |
2003年 | 552篇 |
2002年 | 584篇 |
2001年 | 114篇 |
2000年 | 106篇 |
1999年 | 133篇 |
1998年 | 123篇 |
1997年 | 112篇 |
1996年 | 101篇 |
1995年 | 100篇 |
1994年 | 76篇 |
1993年 | 71篇 |
1992年 | 78篇 |
1991年 | 84篇 |
1990年 | 67篇 |
1989年 | 55篇 |
1988年 | 65篇 |
1987年 | 51篇 |
1986年 | 60篇 |
1985年 | 48篇 |
1984年 | 50篇 |
1983年 | 38篇 |
1982年 | 67篇 |
1981年 | 33篇 |
1980年 | 29篇 |
1979年 | 40篇 |
1978年 | 42篇 |
1977年 | 39篇 |
1975年 | 33篇 |
1973年 | 31篇 |
1971年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Georges Dellatolas Lucia Willadino Braga Ligia do Nascimento Souza Gilberto Nunes Filho Elizabeth Queiroz Gerard Deloche 《Journal of the International Neuropsychological Society》2003,9(5):771-782
The effect of the degree of illiteracy (complete or incomplete) on phonological skills, verbal and visual memory and visuospatial skills is examined in 97 normal Brazilian adults who considered themselves illiterate, and 41 Brazilian school children aged 7 to 8 years, either nonreaders or beginning readers. Similar literacy effects were observed in children and in adults. Tasks involving phonological awareness and visual recognition memory of nonsense figures distinguish the best nonreaders and beginning readers. Children performed better than adults at oral repetition of short items and figure recall, and adults better than children at semantic verbal fluency, digit span, and word list recall. A principal component analysis of the correlations between tasks showed that phonological awareness/reading, phonological memory/oral repetition, and semantic verbal memory/fluency tasks, generated different components. The respective role of culturally based preschool activities and literacy on the cognitive functions that are explored in this study is discussed. 相似文献
42.
43.
Objective: To assess how surgery affected the quality of life of patients with acoustic neuromas and to investigate possible predictors of the functional outcome following surgery. Study Design: A questionnaire based on the Glasgow Benefit Inventory was completed by patients randomly selected following acoustic neuroma surgery. Setting: Skull base surgery unit of a university teaching hospital (tertiary referral center). Patients: Fifty-three patients with acoustic tumors (follow-up, 1 to 3 y). Results: With regard to overall quality of life, nine patients (17.4%) reported that it became better, 28 patients (53.8%) worse, and 15 patients (28.8%) that it remained the same. Four patients (7.8%) became better off financially, 15 patients (29.4%) worse, and 32 (62.8%) remained unchanged. Forty-one patients (78.8%) did not change their occupation, and 11 (21.2%) had to change their occupation, mainly because of the adverse effects of the operation. With regard to the age at operation, older patients were found to have better overall quality of life. Moreover, younger patients had worse postoperative financial status and they were more likely to change their occupation after the operation. The tumor size did not significantly affect the overall postoperative quality, but it did affect the postoperative financial status (patients with larger tumors were more likely to have worse postoperative financial status). Conclusion: Acoustic neuroma surgery has a significant impact on patients' overall quality of life. Surgeons proposing to operate on small tumors should not assume that the impact on patients' life will be necessarily less than that following the removal of larger tumors. All patients, especially in the younger age group, should be prepared and thoroughly informed about the consequences of the operation on their quality of life. 相似文献
44.
Gabriel Gandolfo Gerard Lambeau Michel Lazdunski Claude Gottesmann 《Basic & clinical pharmacology & toxicology》1996,78(5):341-347
Abstract: Three phospholipase A2 (PLA2s), OS1 and OS1 purified from the taipan snake venom Oxyuranus scutellatus scutellatus and bee venom PLA2 were injected to rats by the intracerebroventricular route. OS1 showed no sign of neurotoxicity at doses at which OS2 and bee venom PLA2 produced multiform dose-dependent behavioural effects including motor disturbances (stereotyped movements), compulsive scratching, convulsions and breathing difficulties. EEG recordings showed at the very time when the animal was motionless the induction of several episodes of a low frequency hippocampal theta rhythm, index of long-term changes in synaptic neuroplasticity. Spike-wave discharges were also produced but the occurrence was not systematic. These seizures were often accompanied with behavioural convulsions. Blockers of NMDA receptors and drugs modifying the GABAergic transmission could not abolish the neurotoxic effects of PLA2s except for diazepam (10 mg/kg intraperitoneally) that prevented only OS2-induced disturbances. Blockers of L-type Ca2+ channels and K+ channel openers were also without effect. The toxicity of OS2 and bee venom PLA2 is probably due to their initial specific binding to their neuronal receptor sites. 相似文献
45.
46.
Kenneth D. Murphy M.D. Gerard McCrohan Deborah A. DeMarta Nitin B. Shirodkar Oun J. Kwon Paramjit S. Chopra 《Cardiovascular and interventional radiology》1996,19(2):123-127
We report a case of the heparin-induced thrombocy-topenia and thrombosis syndrome presenting with acute ischemia of a lower
limb. The patient was successfully treated by withdrawal of heparin products, intraarterial urokinase, and platelet anti-aggregation
therapy consisting of Dextran and aspirin. 相似文献
47.
James G. Docherty Rosamund Carter Christopher D. Sheldon J. Stuart Falconer L. Christopher Bainbridge A. Gerard Robertson David S. Soutar 《Head & neck》1993,15(6):553-556
We examined the internal jugular veins in three groups of patients who had undergone (1) a functional neck dissection and radiotherapy, (2) a functional neck dissection alone, or (3) radiotherapy alone, using a noninvasive color Doppler ultrasound scan. The internal jugular veins were ultrasonically bilaterally normal in 18% of patients who had undergone a functional neck dissection and radiotherapy, in 88% of patients who had undergone a functional neck dissection alone, and in 57% of patients who had undergone radiotherapy alone. The combination of a functional neck dissection and radiotherapy significantly affected the internal jugular vein when compared with a functional neck dissection alone. 相似文献
48.
Effect of cigarette smoking on the specific antibody response in pigeon fanciers. 总被引:2,自引:1,他引:1 下载免费PDF全文
Titres of circulating IgG antibodies to pigeon gammaglobulin and end expired carbon monoxide concentrations were measured in 86 pigeon fanciers attending the "Show of the Year." Antibody levels were significantly higher in non-smokers and in those with end expired carbon monoxide concentrations below 10 parts per million. 相似文献
49.
The effects of monoamine oxidase inhibitors (MAOIs) that selectively inhibit the MAO-A or MAO-B forms of MAO were studied in rats performing under a differential-reinforcement-of-low-rate 72-s (DRL 72-s) schedule of reinforcement. Clorgyline and CGP11305A, irreversible and reversible MAO-A inhibitors, respectively, increased the reinforcement rate, decreased the response rate, and enhanced temporal discrimination. The irreversible MAO-B inhibitor (–)-deprenyl did not produce similar effects. Pargyline did not increase the reinforcement rate at low doses that selectively inhibit MAO-B, but did increase the reinforcement rate at doses that inhibit MAO-A by more than 90%. The present results are in accord with clinical data demonstrating that MAO-A inhibitors are effective therapeutic agents in treating depression while MAO-B inhibitors are of questionable antidepressant efficacy. The present findings provide further evidence that the DRL 72-s schedule may be useful both as a screen for identifying new antidepressants and for investigating the neurochemical effects of antidepressant drugs that are responsible for their therapeutic effects. 相似文献
50.
Berner Bret Wilson Donald R. Guy Richard H. Mazzenga Gerard C. Clarke Frank H. Maibach Howard I. 《Pharmaceutical research》1988,5(10):660-663
The relationship between pK
a and skin irritation in man is studied for a homologous series of benzoic acid derivatives, which permeate through human skin at comparable rates (15–88 µg/cm2/hr). Skin irritation and pK
a are correlated for pK
a 4. Laser Doppler velocimetric assessment of skin blood flow, color meter readings, erythema, edema, and the primary irritation index are all linearly correlated and related to pK
a, erythema at 24 hr appears to be the most sensitive parameter to variation in pK
a when pK
a 4. 相似文献