全文获取类型
收费全文 | 1657780篇 |
免费 | 119578篇 |
国内免费 | 7497篇 |
专业分类
耳鼻咽喉 | 23271篇 |
儿科学 | 49798篇 |
妇产科学 | 47277篇 |
基础医学 | 239032篇 |
口腔科学 | 47078篇 |
临床医学 | 141177篇 |
内科学 | 326803篇 |
皮肤病学 | 34738篇 |
神经病学 | 125737篇 |
特种医学 | 64464篇 |
外国民族医学 | 475篇 |
外科学 | 256492篇 |
综合类 | 42611篇 |
现状与发展 | 9篇 |
一般理论 | 356篇 |
预防医学 | 111128篇 |
眼科学 | 38908篇 |
药学 | 130474篇 |
45篇 | |
中国医学 | 7071篇 |
肿瘤学 | 97911篇 |
出版年
2018年 | 17412篇 |
2017年 | 13315篇 |
2016年 | 14626篇 |
2015年 | 17411篇 |
2014年 | 23786篇 |
2013年 | 33250篇 |
2012年 | 46346篇 |
2011年 | 49078篇 |
2010年 | 29308篇 |
2009年 | 27342篇 |
2008年 | 45884篇 |
2007年 | 49561篇 |
2006年 | 49728篇 |
2005年 | 48126篇 |
2004年 | 45615篇 |
2003年 | 44304篇 |
2002年 | 43355篇 |
2001年 | 83173篇 |
2000年 | 85228篇 |
1999年 | 72087篇 |
1998年 | 19325篇 |
1997年 | 17133篇 |
1996年 | 16851篇 |
1995年 | 15758篇 |
1994年 | 14783篇 |
1993年 | 13537篇 |
1992年 | 55542篇 |
1991年 | 53740篇 |
1990年 | 52666篇 |
1989年 | 51390篇 |
1988年 | 47470篇 |
1987年 | 46274篇 |
1986年 | 43797篇 |
1985年 | 41528篇 |
1984年 | 30194篇 |
1983年 | 25917篇 |
1982年 | 14771篇 |
1981年 | 12913篇 |
1979年 | 27628篇 |
1978年 | 18911篇 |
1977年 | 16453篇 |
1976年 | 15005篇 |
1975年 | 16647篇 |
1974年 | 19469篇 |
1973年 | 18709篇 |
1972年 | 17921篇 |
1971年 | 16806篇 |
1970年 | 15562篇 |
1969年 | 15082篇 |
1968年 | 14076篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
961.
962.
963.
With the increased use of indwelling central venous catheters, increasing numbers of cases of Rhodotorula fungemia have been observed in patients with neoplasia and neutropenia. In most patients with catheter-related Rhodotorula fungemia, the condition has been treated with broadspectrum antibiotics. We report two cases of central venous catheter-related
Rhodotorula rubra fungemia that occurred in patients with acute myeloblastic leukemia. Both patients were in a state of neutropenia. One patient
was treated with amphotericin B and his central venous catheter was removed, but he died of Klebsiella pneumoniae bacteremia. The other patient was treated with amphotericin B and discharged, with a central venous catheter, after recovery
from neutropenia. Although the management of catheter-related Rhodotorula fungemia infections remains controversial, resolution of the underlying disease is more important than catheter removal for
recovery from Rhodotorula rubra fungemia.
Received: August 22, 2001 / Accepted: October 8, 2001 相似文献
964.
Thomas L Eggerman Traci Heath Mondoro Jay N Lozier Jaroslav G Vostal 《Human gene therapy》2002,13(1):125-128
Adenoviruses are commonly used as vectors in human clinical gene therapy trials. High doses of intravenous adenovirus vectors have been associated with development of thrombocytopenia of undetermined origin. Viral internalization requires the presence cell surface integrins, alpha(v)beta(3) or alpha(v)beta(5), that can blind ligands with a arginine-glycine-aspartic acid (RGD) sequence. This sequence is found in the adenovirus penton base. Platelets express the alpha(v)beta(3) integrin and other integrins that bind the RGD sequence of ligands such as fibrinogen, laminin, vitronectin, and von Willebrand factor (vWF). Platelet aggregation is mediated, in part, by the binding of the RGD sequence of fibrinogen to a platelet surface integrin, glycoprotein IIb/IIIa (GP IIb/IIIa). We investigated whether adenovirus particles could interfere with or potentiate agonist-induced platelet aggregation. Incubation of platelet-rich plasma with adenovirus under stirred conditions did not promote spontaneous aggregation. The addition of physiological platelet agonists, ADP, collagen, or epinephrine, induced platelet aggregation. However, the presence of adenovirus in a wide range of concentrations did not inhibit or potentiate agonist-induced aggregation. These results suggest that the adenovirus-associated thrombocytopenia observed in vivo is independent of a direct effect of the virus on platelet aggregation. 相似文献
965.
966.
Hinrich Böhner Detlef Kindgen-Milles Andreas Grust Rolf Buhl Wolf-Christian Lillotte Barbara T. Müller Eckhard Müller Günter Fürst Wilhelm Sandmann 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2002,387(1):21-26
BACKGROUND: The efficacy of nasal continuous positive airway pressure (nCPAP) as a prophylactic method for preventing cardiopulmonary complications after major vascular surgery has not been investigated. PATIENTS/METHODS: In a prospective randomized trial, 204 patients undergoing elective midline laparotomy for vascular surgery were randomized to receive standard therapy ( n=105) or additional prophylactic nCPAP ( n=99) for the first postoperative night. Postoperative oxygenation, incidence of severe cardiac, and pulmonary complications, length of intensive care surveillance and length of total postoperative hospital stay (LOS) were compared. RESULTS: Prophylactic nCPAP significantly reduced the number of patients with severe oxygenation disturbances defined as paO(2) < 70 mmHg with FiO(2) > or = 0.7 (5 versus 17, P=.01). There were no differences with respect to death, cardiac and pulmonary complications, length of intensive care surveillance or LOS. CONCLUSION: Prophylactic 12 h nCPAP significantly reduces the occurrence of postoperative oxygenation disturbances but has no effect on cardiac or pulmonary complications, need for intensive care, LOS or mortality after major vascular surgery. 相似文献
967.
G. Biswas S. K. Ghosh S. Mukhopadhyay H. Bora 《Indian journal of otolaryngology and head and neck surgery》2002,54(3):193-195
Out of 36511 patients attending the ENT OHD of R. G,. Aur Medical Callege & Hospital. Kolkata, in one year 0.08% patients
were found tuning naspharyngeal mass. 30 cases of nasopharyngeal mass were studied. The peak incidence of nasopharyngeal mass
was in the age group between II to 20 years (40%). The incidence in males (73%) was more than females(27%). The maximum ineldence
was found among students (74%). Commonest ntuopharyngeal nuns teas antrochoanal polyp (30%). Next commlon masses were adenoids
(23%)Juvenile angwfibroma(20%) and nasophartngeal carcinoma (13%). Nasal obstruction was the main presenting symptom(83%)
followed by epistaxis (40%). 相似文献
968.
F. Berndsen D. Arvidsson L.-K. Enander C.-E. Leijonmarck U. Wingren C. Rudberg S. Smedberg G. Wickbom A. Montgomery 《Hernia》2002,6(2):56-61
Interest in inguinal hernia surgery has increased significantly with the introduction of new operating techniques during
the past decade. This multicenter study compared short-term results in patients treated by the laparoscopic transabdominal
preperitoneal patch technique (TAPP; n=518) and the Shouldice technique (n=524). We evaluated demographics, operative data, complications, hospital stay, postoperative pain, use of analgesics, functional
status, sick leave, and complaints up to 3 months postoperatively. The median operating time was shorter in the Shouldice
group (55 vs. 65 min), but there were no significant differences in complication rates, and major complications were rare.
The hospital stay was 1 day or less in over 98% of cases in both groups, but more operations were performed on outpatient
basis in the Shouldice group. In the TAPP group postoperative pain and analgesic consumption were less, postoperative functional
status was better, and sick leave was shorter (10 vs. 14 days). These results show that the two methods are equally safe and
have few major complications. The TAPP operation is associated with less postoperative pain, better postoperative functional
status, and shorter sick leave, but at the price of a longer operating time.
Electronic Publication 相似文献
969.
Antonio Rivera Antonio Yáñez Gloria León-Tello Constantino Gil Silvia Giono Eduardo Barba Lilia Cedillo 《BMC musculoskeletal disorders》2002,3(1):15-7
Background
Mycoplasma fermentans has been associated with rheumatoid arthritis. Recently, it was detected in the joints and blood of patients with rheumatoid arthritis, but it is not clear yet how the bacteria enter the body and reach the joints. The purpose of this study was to determine the ability of M. fermentans to induce experimental arthritis in rabbits following inoculation of the bacteria in the trachea and knee joints. 相似文献970.