Access to Social Protection by People Living with,at Risk of,or Affected by HIV in Eswatini,Malawi, Tanzania,and Zambia: Results from Population-Based HIV Impact Assessments

AIDS and Behavior - We aimed to measure social protection coverage among the general population, women and men living with HIV (WLHIV, MLHV), female and male sex workers (FSW, MSW), men who have...     

A case of somatostatinoma: responses to food and SMS 201-995 administration

Plasma somatostatin response to food and the administration of the long-acting somatostatin analogue SMS 201-995, as well as pituitary responses to insulin-induced hypoglycemia, growth hormone-releasing hormone (GHRH) and thyrotropin-releasing hormone (TRH), were assessed in a 60-year-old woman with biopsy-proven metastatic somatostatinoma. SMS 201-995 alone did not change plasma somatostatin-like immunoreactivity (SRIF), but levels of low-molecular-weight forms (SRIF-14 and SRIF-28) more than doubled in response to a standard meal. This postprandial response was not affected by pretreatment with SMS 201-995. Although a growth hormone response to insulin-induced hypoglycemia and supramaximal GHRH was absent, the patient's thyroid-stimulating hormone response to TRH was normal. These results suggest that somatostatin analogues may not influence tumor autonomy and that a SRIF response to food may contribute to early satiety in patients with somatostatinoma. In addition, the long-term use of somatostatin analogues to suppress hormone production by other peptide-secreting tumors may not have predictable results.     

Lepidapedon sereti n. sp. (Digenea: Lepidapedidae) in Coelorinchus sereti (Gadiformes: Macrouridae) from deep waters off Vanuatu

Lepidapedon sereti n. sp. is described from the macrourid Coelorinchus sereti from the deep water off Vanuatu. It is placed in the Elongatum group and Elongatum subgroup. It differs from the other species described in this subgroup by the distinctly dorsally subterminal excretory pore. It also differs from other species in combinations of size, excretory vesicle length, proportions of forebody, post-testicular region and other metric features. This constitutes the first record of a Lepidapedon (sensu stricto) from the Central Western Pacific Ocean.