全文获取类型
收费全文 | 3015篇 |
免费 | 134篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 59篇 |
儿科学 | 67篇 |
妇产科学 | 32篇 |
基础医学 | 605篇 |
口腔科学 | 158篇 |
临床医学 | 351篇 |
内科学 | 518篇 |
皮肤病学 | 119篇 |
神经病学 | 210篇 |
特种医学 | 119篇 |
外科学 | 347篇 |
综合类 | 29篇 |
预防医学 | 161篇 |
眼科学 | 62篇 |
药学 | 200篇 |
中国医学 | 4篇 |
肿瘤学 | 115篇 |
出版年
2022年 | 30篇 |
2021年 | 58篇 |
2020年 | 31篇 |
2019年 | 37篇 |
2018年 | 29篇 |
2017年 | 35篇 |
2016年 | 39篇 |
2015年 | 56篇 |
2014年 | 55篇 |
2013年 | 74篇 |
2012年 | 115篇 |
2011年 | 116篇 |
2010年 | 60篇 |
2009年 | 78篇 |
2008年 | 136篇 |
2007年 | 146篇 |
2006年 | 151篇 |
2005年 | 152篇 |
2004年 | 117篇 |
2003年 | 161篇 |
2002年 | 135篇 |
2001年 | 109篇 |
2000年 | 101篇 |
1999年 | 99篇 |
1998年 | 26篇 |
1997年 | 37篇 |
1996年 | 26篇 |
1995年 | 20篇 |
1993年 | 20篇 |
1992年 | 51篇 |
1991年 | 37篇 |
1990年 | 48篇 |
1989年 | 54篇 |
1988年 | 38篇 |
1987年 | 32篇 |
1986年 | 34篇 |
1985年 | 33篇 |
1984年 | 22篇 |
1979年 | 20篇 |
1976年 | 21篇 |
1974年 | 24篇 |
1973年 | 21篇 |
1972年 | 21篇 |
1970年 | 22篇 |
1885年 | 18篇 |
1880年 | 32篇 |
1879年 | 21篇 |
1877年 | 21篇 |
1876年 | 21篇 |
1875年 | 18篇 |
排序方式: 共有3156条查询结果,搜索用时 30 毫秒
31.
32.
Roger T Anderson Lari Wenzel Ann P Walker Andrea Ruggiero Ronald T Acton Mark A Hall Diane C Tucker Elizabeth Thomson Barbara Harrison Edmund Howe Joan Holup Catherine Leiendecker-Foster Tara Power Paul Adams 《Genetics in medicine》2006,8(11):681-687
PURPOSE: Assess the quality of life impact of receiving indeterminate test results for hemochromatosis, a disorder involving HFE genetic mutations and/or elevated serum transferrin saturation and ferritin. METHODS: The study sample was from the Hemochromatosis and Iron Overload Screening Study, a large observational study of hemochromatosis among primary care patients in the US and Canada using HFE genotype and serum transferrin saturation and ferritin screening. Study subjects included 2,304 patients found with hemochromatosis risk of uncertain clinical significance. Assessed was SF-36 general health and emotional well-being before screening and six weeks after participants received their test results. Health worries were assessed after screening. RESULTS: Of the study subjects, 1,268 participants (51.5%) completed both assessments. Compared to normal controls, those with HFE mutations or elevated serum transferrin saturation and ferritin levels of uncertain significance were more likely to report diminished general health and mental well-being, and more health worries. These effects were associated with participants' belief of having tested positive for hemochromatosis or iron overload. CONCLUSION: Notification of indeterminate results from screening may be associated with mild negative effects on well-being, and might be a potential participant risk in screening programs for disorders with uncertain genotype-phenotype. 相似文献
33.
The modulation of monosynaptic forelimb reflexes by tonic neck positions was investigated in cats with the head fixed.Lateral flexion of the body in a horizontal plane markedly facilitates reflexes of the deep radial nerve (DR) in the ipsilateral forelimb, while the antagonistic ulnar nerve (ULN) reflexes are strongly inhibited. Opposite effects are seen after contralateral body movement.Dorsiflexion of the body clearly increases DR-reflexes and exerts a reciprocal although more pronounced inhibition on ULN reflexes. Opposite effects appear after ventriflexion.The reflex modulation starts with head-body displacements of approximately 5° and increases with increasing angles. Furthermore reflex modulation does not depend on the intact cerebrum and cerebellum. The comparison of forelimb and hindlimb reflexes shows a decrease of the neck influences along the spinal cord.Supported by Sonderforschungsbereich Hirnforschung und Sinnes-physiology (SFB 70) der Deutschen Forschungsgemeinschaft (DFG).Essential parts of this paper will be submitted by A. F. as a thesis to the Faculty of Medicine, Freiburg/Breisgau, Germany. 相似文献
34.
Wenzel Mike Yu Hang Uhlig Annemarie Würnschimmel Christoph Wallbach Manuel Becker Andreas Fisch Margit Chun Felix K. H. Meyer Christian P. Leitsmann Marianne 《International urology and nephrology》2021,53(10):2041-2049
International Urology and Nephrology - To test the value of preoperative and postoperative cystatin C (CysC) as a predictor on kidney function after partial (PN) or radical nephrectomy (RN) in... 相似文献
35.
Bernhard Springer Wenzel Waldstein Ulrich Bechler Anna Jungwirth-Weinberger Reinhard Windhager Friedrich Boettner 《The Journal of arthroplasty》2021,36(2):501-506
BackgroundThe present article analyzes the association of the functional anterior cruciate ligament (ACL) status and the overall varus deformity and coronal tibiofemoral subluxation (CTFS) in varus OA of the knee.MethodsOne hundred consecutive knees with varus OA in 84 patients were prospectively included. Knees were divided into two groups, in accordance with the ACL status (functionally sufficient or insufficient). All included patients were potential candidates for unicompartmental knee arthroplasty with predominantly medial compartment OA. Knees with Kellgren/Lawrence ≥ grade 3 in the lateral compartment were excluded leaving 79 knees to be included in this study. Mechanical varus deformity and CTFS were evaluated on AP radiographs and valgus stress radiographs, and compared between the two groups.ResultsKnees with a functionally insufficient ACL had significantly more varus deformity on hip-to-ankle AP standing radiographs (P = .001) and on valgus stress radiographs (P = .017). CTFS on AP standing radiographs was significantly higher (P = .045) in knees with a functionally insufficient ACL. Seventy-three percent (8/11) of the ACL-insufficient knees had a varus deformity of ≥10° and 64% (7/11) of ACL-insufficient knees had CTFS ≥ 6mm. By contrast, only one patient (2%, 1/41) with an insufficient ACL had< 10° varus deformity and a CTFS of < 6mm.ConclusionFunctional ACL insufficiency in osteoarthritic varus knees is associated with greater varus deformity and more advanced CTFS. Seventy-three percent of ACL-insufficient knees had a varus deformity of ≥10° and 64% of ACL-insufficient knees a CTFS of ≥ 6mm. In the work-up for medial unicompartmental knee arthroplasty, functional ACL insufficiency is likely in knees with varus deformity of ≥10° and CTFS of ≥ 6mm. 相似文献
36.
37.
38.
Comparison of microscopy and radiography as gold standards in radiographic caries diagnosis 总被引:1,自引:0,他引:1
OBJECTIVES: To compare the effect of the choice of gold standard on the diagnostic outcome of approximal caries detection in original and compressed digital radiographs. METHODS: 116 extracted teeth radiographed with a storage phosphor system constituted the original images. These images were compressed at 1:20 and 1:33 with the JPEG irreversible compression standard. Five radiologists scored the three sets of images for the presence of approximal caries on a five-rank confidence scale. The radiographic scores were validated by stereomicroscopy (the true gold standard). The individual ROC areas for the five observers were used to select the worst (obsworst) and the best (obsbest) performer: Their scores in the original images were used as the second and third 'gold standards' for the remaining observers. Mean ROC areas for the three observers with the three types of images were calculated using these two new 'gold standards'. Differences between the ROC areas when using microscopy, obsworst, and obsbest as the 'gold standard' were compared. RESULTS: The mean ROC areas in the original images were 0.66, 0.74 and 0.91 using the true gold standard and obsbest and obsworst as the 'gold standards' respectively. The difference between the true gold standard and obsworst was statistically significant (P < 0.001). The mean ROC areas using the true gold standard decreased with increasing compression whereas they were constant or increased using obsworst and obsbest as 'gold standards', respectively. CONCLUSIONS: Accuracy in approximal caries diagnosis was significantly higher when an observer was the 'gold standard' than when the true gold standard was obtained by microscopy. Paradoxically, the compressed, degraded images were more accurate than the originals when an observer was the 'gold standard' while they were less accurate with the true gold standard. Thus, results obtained using observers' scores from the radiographs which are being evaluated, as validation for the presence of caries may mislead the clinician. 相似文献
39.
40.