全文获取类型
收费全文 | 24276篇 |
免费 | 1498篇 |
国内免费 | 158篇 |
专业分类
耳鼻咽喉 | 292篇 |
儿科学 | 754篇 |
妇产科学 | 720篇 |
基础医学 | 2441篇 |
口腔科学 | 712篇 |
临床医学 | 2029篇 |
内科学 | 5294篇 |
皮肤病学 | 515篇 |
神经病学 | 1114篇 |
特种医学 | 802篇 |
外国民族医学 | 9篇 |
外科学 | 4336篇 |
综合类 | 703篇 |
现状与发展 | 1篇 |
一般理论 | 21篇 |
预防医学 | 1684篇 |
眼科学 | 712篇 |
药学 | 2137篇 |
中国医学 | 156篇 |
肿瘤学 | 1500篇 |
出版年
2023年 | 341篇 |
2022年 | 991篇 |
2021年 | 1406篇 |
2020年 | 741篇 |
2019年 | 935篇 |
2018年 | 1248篇 |
2017年 | 758篇 |
2016年 | 784篇 |
2015年 | 872篇 |
2014年 | 1080篇 |
2013年 | 1327篇 |
2012年 | 1838篇 |
2011年 | 1869篇 |
2010年 | 967篇 |
2009年 | 798篇 |
2008年 | 1175篇 |
2007年 | 1265篇 |
2006年 | 1099篇 |
2005年 | 948篇 |
2004年 | 897篇 |
2003年 | 755篇 |
2002年 | 699篇 |
2001年 | 329篇 |
2000年 | 316篇 |
1999年 | 292篇 |
1998年 | 158篇 |
1997年 | 115篇 |
1996年 | 101篇 |
1995年 | 106篇 |
1994年 | 69篇 |
1993年 | 55篇 |
1992年 | 131篇 |
1991年 | 120篇 |
1990年 | 114篇 |
1989年 | 103篇 |
1988年 | 97篇 |
1987年 | 94篇 |
1986年 | 97篇 |
1985年 | 85篇 |
1984年 | 69篇 |
1983年 | 87篇 |
1982年 | 36篇 |
1981年 | 44篇 |
1980年 | 32篇 |
1979年 | 78篇 |
1978年 | 44篇 |
1977年 | 52篇 |
1976年 | 41篇 |
1975年 | 44篇 |
1974年 | 38篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
41.
42.
K elZaki M E Ahmed A M elHassan M A Yousif A H Fahal 《The Journal of tropical medicine and hygiene》1991,94(3):206-209
This prospective study contains clinical and experimental parts. In the clinical study, 125 patients given intramuscular chloroquine for malaria were followed for 2 months in order to detect local injection site complications. Adequate local antiseptic conditions were ensured before giving the injection. Twenty-three patients (18.4%) had minimal local reaction in the form of redness, induration and/or a lump. No pyogenic abscess was noted in contrast to a previous report. In the second part of the study, an experimental animal (Green monkey) was given either chloroquine phosphate, Ampiclox or normal saline intramuscularly. The injection site was later biopsied and histologically examined. Intramuscular chloroquine was found to cause severe inflammatory reactions and muscle necrosis, whereas other injections had very minimal local effects. It is concluded that intramuscular chloroquine causes muscle necrosis which may lead to acute pyogenic abscess if minimal contamination takes place. 相似文献
43.
Ahmed M. Abu El-Asrar Eman S. Kahtani Khalid F. Tabbara 《Documenta ophthalmologica. Advances in ophthalmology》1995,89(4):313-320
In this report we describe, herewith, a patient with primary pigmentary dystrophy of the retina (retinitis pigmentosa) associated with unilateral retinal arteriovenous communication and exudative retinal detachment. The patient had complete resolution of the retinal detachment following laser photocoagulation treatment. Such association has not been previously reported. 相似文献
44.
Kamran Ahmed Ashok Kelshiker Christopher Jenner 《Primary care respiratory journal》2007,16(4):249-251
AIMS AND OBJECTIVES: To screen for, and to treat, depression in COPD patients in a general practice surgery, and to test the feasibility of the screening method. METHODS: We sent The Beck Depression Inventory (BDI) Short-Form Questionnaire to all patients on the COPD register (n=69) by post, excluding those already diagnosed with depression (n=3). We sent appointments to all responders with moderate to severe depression and offered them treatment including antidepressants and pulmonary rehabilitation if the diagnosis was confirmed. RESULTS: Of the 66 patients to whom we sent questionnaires, 43 were returned completed and 13 of these had significant depression (30%). 10 of these patients were contactable and attended for review. The diagnosis of depression was confirmed in all 10 cases. Treatment options were discussed; five chose antidepressant medication, three chose pulmonary rehabilitation and two declined treatment. CONCLUSION: We identified and treated a significant number of depressed COPD patients in a general practice setting using this screening method. This method could have wider applications for screening, although further trials are needed. 相似文献
45.
46.
Jerzy Slowinski Jake Dominik Ryan J. Uitti Zeshan Ahmed Dennis D. Dickson Zbigniew K. Wszolek 《Neuropathology》2007,27(1):73-80
We present a case of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP‐17) harboring the N279K mutation in the MAPT gene from the family known as pallido‐ponto‐nigral degeneration (PPND). This 49‐year‐old man was followed for 17 years. He presented at age 41 years with left leg stiffness and en‐bloc turning. During the course of his illness he developed a constellation of symptoms including parkinsonism, pyramidal signs, vertical gaze palsy, dysphagia, dystonia, personality and cognitive dysfunction, weight loss and mutism. Gross neuropathological examination showed mild atrophy of the cerebral cortex, hippocampal formation, amygdala, thalamus, subthalamic nucleus and depigmentation of the substantia nigra. Microscopy revealed neuronal loss and gliosis in the same regions. Tau immunohistochemistry showed pretangles, numerous threads, grain‐like structures and oligodendroglial tau‐positive inclusions (“coiled bodies”). In the spinal cord the tau pathology was more abundant in gray than white matter. Pretangles and threads were present in the anterior and, to a lesser extent, in the posterior horns. FTDP‐17 should be suspected in patients with a history of familial parkinsonism combined with behavioral and cognitive changes, onset before age 65 years and an aggressive clinical course. 相似文献
47.
The date of delivery in 62 normal pregnant women was predicted by last menstrual period, by ultrasound scan and by the serum concentration of Schwangerschaftsprotein 1 (SP1). It was found that SP1 concentration in the first trimester gave as reliable an indication of when labour would occur as did the last menstrual period or ultrasound scan. 相似文献
48.
M. I. Anjum M. Ahmed N. Shrotri A. Azzopardi G. R. Mufti 《International urology and nephrology》1997,29(3):313-317
The clinico-pathological features of nine urethral and urinary bladder polyps with prostate-type epithelium are described.
The average age of the patients was 46 years. Three patients previously had cystoscopy and the lesion was not noticed on the
initial examination. The commonest presentation in this series was haematuria, dysuria and frequency of micturition. One patient
presented with postmicturition dribble and another with haemospermia. The polyps contained acini and papillae lined by prostate-type
epithelium which was confirmed by immunohistochemical tests for prostate specific antigen and prostate acid phosphatase. In
this series no age versus location relationship could be established. Symptoms resolved following resection or initial biopsy
followed by fulguration. Recurrence is extremely rare. 相似文献
49.
50.
Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome. 总被引:1,自引:1,他引:0
Amr El-Husseini Fathy El-Basuony Ahmed Donia Ihab Mahmoud Nabil Hassan Nagy Sayed-Ahmad Mohamed Sobh 《Nephrology, dialysis, transplantation》2004,19(9):2266-2271
BACKGROUND: The deliberate use of ketoconazole to reduce the need for cyclosporine (CsA) is not new, but it is particularly relevant because of the high cost of CsA. Many studies have documented this benefit in renal and cardiac transplants, but this co-administration has not been reported in patients with nephrotic syndrome. METHODS: This retrospective study included 207 nephrotic patients who were steroid resistant, dependent or frequent relapsers and received CsA therapy. Among these patients 153 received daily ketoconazole therapy in a dose of 50 mg with concomitant decrease of one-third of the CsA dose while 54 patients received CsA alone. The majority of our cases were children (179 were below 18 years) and male to female ratio was 1.7:1. RESULTS: The great majority of the study population received the drugs for 1-2 years. Patients who received CsA and ketoconazole were comparable with those who received CsA alone regarding age, sex, duration of renal disease, renal pathology, severity of nephrotic syndrome, renal function, hepatic function and steroid response. Co-administration of ketoconazole significantly reduced mean doses of CsA by 37% after 1 month and 47% at 1 year with overall net cost savings of 37%. Hepatic functions remained within the normal range in both groups. Additionally, co-administration of ketoconazole significantly improved the response to CsA therapy, successful steroid withdrawal and decreased the frequency of renal impairment. CONCLUSIONS: Co-administration of keto with CsA in idiopathic nephrotic patients significantly reduces CsA costs and may improve its response. 相似文献