Association between age and clinical characteristics of renal cell carcinoma in adult patients

AIM: To study the association between age and clinical characteristics of renal cell carcinoma in adult patients. METHODS: Three hundred and ten patients with renal cell carcinoma were classified into three groups: or=60 years group. The clinical characteristics of the three groups were compared to define the association. RESULTS: The male/female ratio was 1.3/1, 2.0/1, 3.3/1 in the three groups, respectively, and a significant difference appeared when comparing the or=60 years group (P=0.010). The respective percentage of incidental renal cell carcinoma was 27.9%, 43.2%, 31.2%, and it was significantly higher in the 41-59 years group than the >or=60 years group (P=0.047). The incidence of poorly differentiated renal cell carcinoma decreased with age increasing (11.6% vs 5.2% vs 2.7%), and there was significant difference between the or=60 years group (P=0.038). In the 相似文献   

卡维地洛对慢性心衰患者血清中TNF-α和IL-6水平变化的影响

目的观察慢性心衰(CHF)患者血清中TNF-α和IL-6水平的变化、与心功能参数的相关性及卡维地洛对其干预的影响.方法将52例CHF患者分为常规抗心衰治疗组(A组,25例)和在常规抗心衰治疗基础上加用卡维地洛组(B组,27例),卡维地洛起始量6.25mg/d,目标量50mg/d,疗程为12周.另设36例健康体检者为正常对照组.用免疫化学发光仪检测所有CHF患者治疗前后血清TNF-α和IL-6的水平,用彩色多普勒仪测定左心室舒张末期内径(LDVd)与收缩末期内径(LDVs),并由此获得左心室射血分数(LVEF)值.结果CHF患者血清TNF-α[A组(28.2±10.5)ng/L,B组(28.3±11.5)ng/L]、IL-6[A组(216.8±55.6)ng/L,B组(218.9±53.8)ng/L]含量较正常对照组[TNF-α(15.6±4.4)ng/L,IL-6(122.5±39.2)ng/L]明显升高(均P＜0.01).A、B两组治疗后心功能较前有所恢复,TNF-α和IL-6水平有所下降,以B组更为显著(P＜0.01).结论TNF-α、IL-6与CHF的发生发展密切相关,使用卡维地洛后,CHF患者血清中TNF-α、IL-6水平显著下降,心功能得到改善.     

喉癌染色体6q25区域的杂合性丢失和微卫星不稳定性分析

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立体定向开放显微手术治疗脑内致痫小病灶

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小切口有限内固定结合外固定架治疗胫腓骨骨折

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人钠/二羧酸协同转运蛋白3基因调控肾小管上皮细胞线粒体膜电位的研究

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上海人群发病、患病情况分析

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