全文获取类型
收费全文 | 1506篇 |
免费 | 357篇 |
国内免费 | 89篇 |
专业分类
耳鼻咽喉 | 18篇 |
儿科学 | 80篇 |
妇产科学 | 16篇 |
基础医学 | 32篇 |
口腔科学 | 5篇 |
临床医学 | 301篇 |
内科学 | 353篇 |
皮肤病学 | 123篇 |
神经病学 | 245篇 |
特种医学 | 68篇 |
外科学 | 475篇 |
预防医学 | 133篇 |
眼科学 | 2篇 |
药学 | 19篇 |
肿瘤学 | 82篇 |
出版年
2024年 | 5篇 |
2023年 | 30篇 |
2022年 | 5篇 |
2021年 | 30篇 |
2020年 | 45篇 |
2019年 | 17篇 |
2018年 | 93篇 |
2017年 | 85篇 |
2016年 | 88篇 |
2015年 | 97篇 |
2014年 | 168篇 |
2013年 | 156篇 |
2012年 | 52篇 |
2011年 | 66篇 |
2010年 | 109篇 |
2009年 | 151篇 |
2008年 | 93篇 |
2007年 | 42篇 |
2006年 | 49篇 |
2005年 | 34篇 |
2004年 | 18篇 |
2003年 | 23篇 |
2002年 | 19篇 |
2001年 | 74篇 |
2000年 | 85篇 |
1999年 | 49篇 |
1998年 | 39篇 |
1997年 | 61篇 |
1996年 | 51篇 |
1995年 | 41篇 |
1994年 | 20篇 |
1993年 | 12篇 |
1992年 | 11篇 |
1991年 | 16篇 |
1990年 | 11篇 |
1989年 | 2篇 |
1988年 | 3篇 |
1986年 | 1篇 |
1985年 | 1篇 |
排序方式: 共有1952条查询结果,搜索用时 15 毫秒
61.
Raffit Hassan MD Christine Alewine MD PhD Idrees Mian MD Anna Spreafico MD PhD Lillian L. Siu MD FRCPC Carlos Gomez-Roca MD Jean-Pierre Delord MD PhD Antoine Italiano MD PhD Ulrik Lassen MD PhD Jean-Charles Soria MD PhD Rastilav Bahleda MD Anish Thomas MBBS MD Seth M. Steinberg PhD Cody J. Peer PhD William D. Figg PharmD Gerhard Niederfellner PhD Valérie Méresse Naegelen MD Ira Pastan PhD 《Cancer》2020,126(22):4936-4947
62.
63.
64.
Background: The INCAT (Inflammatory Neuropathy Cause and Treatment) disability score is a measure of activity limitation. It is used frequently as a primary endpoint in inflammatory polyneuropathy clinical trials. A comprehensive critical analysis of its measurement properties has not been performed. Methods: Critical analysis of measurement properties. Results: The INCAT disability score was derived based on items from Guy's Neurological Disability Scale (GNDS), a disability measure intended for application in multiple sclerosis. Strengths of the INCAT score include evaluation of upper and lower limb dysfunction, ease of administration (feasibility), high face validity, and high reliability. Weaknesses of the scale include concerns about methodological quality of validation studies; failure to properly capture activity limitations due to proximal arm weakness, or fatigue; heavy individual item weighting; and poor sensitivity for detection of clinically important change. Conclusions: Although the INCAT scale has been an effective tool in inflammatory polyneuropathy studies, its limitations may warrant development of new scales. Muscle Nerve 50:164–169, 2014 相似文献
65.
Maher Saqqur MD MPH FRCPC Georgios Tsivgoulis MD Francois Nicoli MD David Skoloudik MD Vijay K. Sharma MD Vincent Larrue MD Jürgen Eggers MD PhD FAHA Fabienne Perren MD Paris Charalampidis PhD Dale Storie PSL Ashfaq Shuaib MD FRCPC FAHA Andrei V. Alexandrov MD RVT 《Journal of neuroimaging》2014,24(3):209-220
66.
A systematic review of the relationship between glycemic control and necrobiosis lipoidica diabeticorum in patients with diabetes mellitus 下载免费PDF全文
Bhavik D. Mistry BHSc Afsaneh Alavi MSc MD FRCPC Saima Ali BSc Nisha Mistry MD FRCPC FAAD 《International journal of dermatology》2017,56(12):1319-1327
The association of specific skin disorders with diabetes mellitus (DM) has been well established. Current literature suggests that approximately 30–91% of patients with diabetes will experience at least one cutaneous manifestation of this systemic disease in their lifetime. To date, there are limited articles summarizing the link between necrobiosis lipoidica diabeticorum (NLD) prognosis and glycemic control in patients with diabetes. The objective of the study is to summarize and appraise the available evidence assessing the relationship between glycemic control and NLD. A literature search was conducted based on MEDLINE (1946–2015), EMBASE (1980–2015), Google Scholar, and PubMed for publications that described the results of diabetes control and NLD. Further studies were identified from bibliographies of all relevant studies, gray literature, and annual scientific assemblies. All studies investigating the relationship between DM (type 1 and type 2) management and NLD were included. Two reviewers independently extracted data including demographics, type of diabetes management measures (glucose, HbA1c, insulin), comorbidities, and outcome. A total of 622 studies were identified, and 10 studies met the inclusion and exclusion criteria: two case series and eight case reports. Of the 24 patients with NLD, 13 patients reported resolution of NLD after implementing various methods of glycemic control (diabetic diet consisting of 1600 kcal/day [1 patient], insulin regimen [3 patients], and pancreatic transplantation [9 patients]). Glycemic control may have a role in influencing the prognosis of necrobiosis lipoidica in patients with diabetes; however, there is currently insufficient evidence to support or refute this claim. 相似文献
67.
68.
69.
The management of ventricular tachyarrhythmias has changed significantly over the past several decades. The advent of readily available implantable cardioverter defibrillators (ICDs) has had the greatest effect, with important mortality effects in patients with ventricular tachycardia and structural heart disease. ICDs have been shown to reduce sudden death in patients with ischemic and nonischemic cardiomyopathies; evidence of adverse consequences of ICD shocks, however, is mounting. In addition to the negative effects on patient-reported quality of life, anxiety, and depression, frequent ventricular arrhythmias and ICD shocks have also been associated with increased mortality. It is therefore important to identify and implement effective ventricular tachycardia-suppressive strategies. Antiarrhythmic drugs represent one such method, but are challenged by unfavourable side effect profiles and proarrhythmic risk. Catheter ablation of ventricular tachycardia is now a well-accepted intervention, which has been demonstrated to reduce recurrent arrhythmias. Questions persist regarding the optimal role for ablation compared with drug therapy. 相似文献
70.
Matthew Stern MD Werner Poewe MD C. Warren Olanow MD FRCPC Wolfgang Oertel MD José Obeso MD PhD Kenneth Marek MD Irene Litvan MD Anthony E. Lang OC MD FRCPC Glenda Halliday PhD Christopher G. Goetz MD Thomas Gasser MD Bruno Dubois MD PhD Piu Chan MD PhD Bastiaan R. Bloem MD PhD Charles H. Adler MD PhD Günther Deuschl MD 《Movement disorders》2015,30(12):1591-1601
This document presents the Movement Disorder Society Clinical Diagnostic Criteria for Parkinson's disease (PD). The Movement Disorder Society PD Criteria are intended for use in clinical research but also may be used to guide clinical diagnosis. The benchmark for these criteria is expert clinical diagnosis; the criteria aim to systematize the diagnostic process, to make it reproducible across centers and applicable by clinicians with less expertise in PD diagnosis. Although motor abnormalities remain central, increasing recognition has been given to nonmotor manifestations; these are incorporated into both the current criteria and particularly into separate criteria for prodromal PD. Similar to previous criteria, the Movement Disorder Society PD Criteria retain motor parkinsonism as the core feature of the disease, defined as bradykinesia plus rest tremor or rigidity. Explicit instructions for defining these cardinal features are included. After documentation of parkinsonism, determination of PD as the cause of parkinsonism relies on three categories of diagnostic features: absolute exclusion criteria (which rule out PD), red flags (which must be counterbalanced by additional supportive criteria to allow diagnosis of PD), and supportive criteria (positive features that increase confidence of the PD diagnosis). Two levels of certainty are delineated: clinically established PD (maximizing specificity at the expense of reduced sensitivity) and probable PD (which balances sensitivity and specificity). The Movement Disorder Society criteria retain elements proven valuable in previous criteria and omit aspects that are no longer justified, thereby encapsulating diagnosis according to current knowledge. As understanding of PD expands, the Movement Disorder Society criteria will need continuous revision to accommodate these advances. © 2015 International Parkinson and Movement Disorder Society 相似文献