首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1047542篇
  免费   69393篇
  国内免费   2645篇
耳鼻咽喉   15224篇
儿科学   34254篇
妇产科学   29938篇
基础医学   147716篇
口腔科学   28994篇
临床医学   85947篇
内科学   209635篇
皮肤病学   23103篇
神经病学   85389篇
特种医学   44141篇
外国民族医学   357篇
外科学   166519篇
综合类   20107篇
一般理论   283篇
预防医学   71601篇
眼科学   24258篇
药学   74194篇
中国医学   2138篇
肿瘤学   55782篇
  2018年   11615篇
  2017年   9258篇
  2016年   10587篇
  2015年   11998篇
  2014年   15812篇
  2013年   24053篇
  2012年   33103篇
  2011年   34285篇
  2010年   20676篇
  2009年   19102篇
  2008年   33062篇
  2007年   35393篇
  2006年   35595篇
  2005年   35568篇
  2004年   33927篇
  2003年   33078篇
  2002年   32523篇
  2001年   46268篇
  2000年   47551篇
  1999年   40590篇
  1998年   11319篇
  1997年   10270篇
  1996年   9929篇
  1995年   9125篇
  1994年   8722篇
  1993年   8185篇
  1992年   30170篇
  1991年   28880篇
  1990年   28266篇
  1989年   27085篇
  1988年   25076篇
  1987年   24704篇
  1986年   23616篇
  1985年   22494篇
  1984年   16820篇
  1983年   14299篇
  1982年   8683篇
  1979年   15755篇
  1978年   11065篇
  1977年   9361篇
  1976年   8770篇
  1975年   9872篇
  1974年   11633篇
  1973年   11042篇
  1972年   10548篇
  1971年   9772篇
  1970年   9370篇
  1969年   8739篇
  1968年   8361篇
  1967年   7730篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
101.
Journal of Behavioral Medicine - Understanding associations between mothers’ and children’s physical activity and sedentary behavior on more fine-grained timescales can provide insights...  相似文献   
102.
103.
In both adults and children with diabetes, technologies such as continuous subcutaneous insulin infusion using insulin pumps and continuous glucose monitoring can help improve diabetes control, reduce hypoglycaemia and improve quality of life. Access to these technologies in the UK is very variable. Some technologies are recommended by the National Institute for Health and Care Excellence, while others have not been appraised, and new technologies are emerging all the time. Additionally, different guidelines for adults and children further complicate access to diabetes technology in the transition from paediatric to adult care. Against this background, Diabetes UK and NHS England have brought together a multidisciplinary group of experts, including clinicians and people with diabetes, to develop this consensus guideline, combining the different technologies into a common pathway to aid clinical and policy decision‐making. We created a pathway that supports the incremental addition of technology as monotherapy and then dual therapy in the same way that we incrementally add in therapeutic agents to support people with Type 2 diabetes to achieve their personalized glycaemic targets. The pathway emphasizes the importance of structured education, specialist support and appropriate access to psychological therapies, as essential pillars for optimized use of diabetes‐related technology, and recommends the re‐evaluation of its use when the individual is unable either to use the technology appropriately or to achieve the intended outcomes. This pathway is endorsed by UK‐wide clinical and patient associations and we recommend that providers and commissioners use it to ensure the right individual with diabetes has access to the right technology in a timely way to help achieve better outcomes.  相似文献   
104.
105.
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Gefahrstoffe sind in der Arbeitswelt allgegenwärtig. Beschäftigte aus allen Branchen sind bei ihrer Arbeit mit...  相似文献   
106.
107.

Purpose

A hydrogel rectal spacer (HRS) is a medical device that is approved by the U.S. Food and Drug Administration to increase the separation between the prostate and rectum. We conducted a cost-effectiveness analysis of HRS use for reduction in radiation therapy (RT) toxicities in patients with prostate cancer (PC) undergoing external beam RT (EBRT).

Methods and Materials

A multistate Markov model was constructed from the U.S. payer perspective to examine the cost-effectiveness of HRS in men with localized PC receiving EBRT (EBRT alone vs EBRT + HRS). The subgroups analyzed included site of HRS placement (hospital outpatient, physician office, ambulatory surgery center) and proportion of patients with good baseline erectile function (EF). Data on EF, gastrointestinal and genitourinary toxicities incidence, and potential risks associated with HRS implantation were obtained from a recently published randomized clinical trial. Health utilities and costs were derived from the literature and the 2018 Physician Fee Schedule and were discounted 3% annually. Quality-adjusted life years (QALYs) and costs were modeled for a 5-year period from receipt of RT. Probabilistic sensitivity analysis and value-based threshold analyses were conducted.

Results

The per-patient 5-year incremental cost for spacers administered in a hospital outpatient setting was $3578, and the incremental effectiveness was 0.0371 QALYs. The incremental cost-effectiveness ratio was $96,440/QALY for patients with PC undergoing HRS insertion in a hospital and $39,286/QALY for patients undergoing HRS insertion in an ambulatory facility. For men with good baseline EF, the incremental cost-effectiveness ratio was $35,548/QALY and $9627/QALY in hospital outpatient and ambulatory facility settings, respectively.

Conclusions

Based on the current Medicare Physician Fee Schedule, HRS is cost-effective at a willingness to pay threshold of $100,000. These results contain substantial uncertainty, suggesting more evidence is needed to refine future decision-making.  相似文献   
108.
109.
110.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号