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91.
目的 研究含新的mucA突变基因黏液型铜绿假单胞菌(PAE17)在不同条件下形成的生物被膜,以了解新的mucA突变基因对铜绿假单胞菌生物被膜的影响.方法 采用PIA平板法鉴定3种铜绿假单胞菌的黏液表型,色氨酸反应法测定其胞外多糖蛋白复合物的合成量;刚果红染色法和静态培养法分别观察其在固态及液态条件下形成的生物被膜;采用电转化法将绿色荧光蛋白表达质粒(pGFPuv)导入上述3种病原菌中,应用改良平板法建立体外生物被膜模型,激光共聚焦显微镜观察不同时问点生物被膜的形成.结果 PAE17与PDO300呈现明显的黏液表型,其胞外多糖的产量(101.6 μg/ml、118.3μg/ml)显著高于PAEO1(56.3μg/ml),但无论在固态、液态和改良平板法体外生物被膜模型中,PAE17形成的生物被膜均与PDO300迥异,而表现类似PAEO1.结论 新的mucA突变基因可能存在藻酸盐以外的其他途径调节生物被膜的形成. 相似文献
92.
Production and identification of iturin A lipopeptide from Bacillus methyltrophicus TEB1 for control of Phoma tracheiphila
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93.
Effect of antipsoriatic therapy on oxidative stress index and sialic acid levels in patients with psoriasis
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94.
Familial gastrointestinal stromal tumors,lentigines, and café‐au‐lait macules associated with germline c‐kit mutation treated with imatinib
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96.
Wahbi Ben Salha Eya Moussaoui Lamia Oualha Jihed Anoun Nabiha Douki 《Clinical Case Reports》2021,9(11)
Drug reaction with eosinophilia and systemic symptoms (DRESS) is a distinct part of severe cutaneous adverse reactions (SCARs). It is characterized by fever, rash, hematologic abnormalities, lymphadenopathy, or/and different degrees of visceral organ involvement. Its diagnosis is particularly challenging due to the variability of its clinical presentations and its long latency period (2–6 weeks). Allopurinol, an uric acid‐lowering drug, has been incriminated in several cases of allopurinol‐induced DRESS syndrome. Through this paper, we present a case of allopurinol‐induced DRESS syndrome with initial oral mucosal involvement. A 69‐year‐old female patient presented with an erosive cheilitis that started 1 week prior to his presentation. The cheilitis was associated with maculopapular rash and fever. She started taking allopurinol, as treatment of Gout, 6 weeks before hospitalization. The histologic findings obtained from skin biopsy were consistent with a toxic drug reaction. A complete blood count (CBC) showed a moderate eosinophilia. Alteration of renal function was also noted, and the diagnosis of allopurinol‐induced DRESS syndrome was made. Systemic corticosteroid therapy was therefore started. The patient completely recovered and had been healthy for 3 years before developing a recurrence after re‐challenge with allopurinol. 相似文献
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98.
Melissa S. Doud Reni Grimes-Zeppegno Enrique Molina Nancimae Miller Danajeyan Balachandar Lisa Schneper Robert Poppiti Kalai Mathee 《International journal of medical sciences》2009,6(6):301-304
Klebsiella pneumoniae isolated in community-acquired pneumonia is increasingly found in primary pyogenic liver abscesses. The presence of magA in K. pneumoniae has been implicated in hypermucoviscosity and virulence of liver abscess isolates. The K2 serotype has also been strongly associated with hypervirulence. We report the isolation of non-magA, K2 K. pneumoniae strain from a liver abscess of a Saint Kitt''s man who survived the invasive syndrome. 相似文献
99.