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21.
Gijs I. T. Iordens Esther M. M. Van Lieshout Bernd C. Van Es Niels W. L. Schep Roelf S. Breederveld Peter Patka Dennis Den Hartog 《Strategies in trauma and limb reconstruction (Online)》2013,8(3):141-147
Most recent studies on procedures for stabilizing the glenohumeral joint focus on arthroscopic techniques. A relatively simple open procedure is the modified Putti-Platt procedure. The aim of these retrospective case series was to evaluate the functional outcome, patient satisfaction, and quality of life of patients who underwent this procedure. After a median follow-up time of 4.7 (P25–P75 1.7–6.8) years, fifty-one patients could be enrolled with a mean age of 25 (21–39) years. Five patients (10 %) reported re-dislocations. The median Constant score for the affected side was 84 (P25–P75 75–91). Median loss of motion in abduction, elevation, external rotation, and external rotation in 90° of abduction did not exceed 10° when compared to the healthy shoulder. A median Rowe score of 92 (P25–P75 75–95) was measured. The WOSI score and SF-36 showed excellent quality of life. The VAS proved high patient satisfaction with the outcome; 7.9 (6.8–9.5). We concluded that the modified Putti-Platt procedure leads to excellent outcome scores and only marginal restriction in range of motion combined with a high patient satisfaction. Our data prove that excellent results can be obtained with a relatively simple open procedure. 相似文献
22.
Fenugreek is among the oldest medicinal and culinary plants. It is widely used in Morocco and the Mediterranean area. In herbal medicine, the seeds of this plant are shown to stimulate appetite in pregnant women to treat inflammation, dysentery, dyspepsia, chronic cough, bronchitis, neuralgia, and facilitate childbirth and also as galactagogue. Unfortunately, few scientific data are available from the literature to confirm therapeutic properties of fenugreek. The early adverse events related to the consumption of this plant were reported between March and August 2006 by the Moroccan Pharmacovigilance Centre; Skalli reported eight cases of malformations (hydrocephalus and spina bifida) coinciding with fenugreek ingestion during pregnancy. A lot of studies have subsequently confirmed this clinical fact. The aim of this study is to report local and national data on the relationship between the consumption of fenugreek during pregnancy and the appearance of neural tube defects based on studies that confirm this relationship. 相似文献
23.
N. Garnefski MSc PhD V. Kraaij MSc PhD M. J. Schroevers MSc PhD J. Aarnink MSc D. J. van der Heijden MD S. M. van Es MSc PhD 《Behavioral medicine (Washington, D.C.)》2013,39(3):79-86
The authors studied the relationships among cognitive coping strategies, goal adjustment processes (disengagement and reengagement), and depressive symptomatology in a sample of 139 patients who had experienced a first-time acute myocardial infarction between 3 and 12 months before data assessment. They assessed cognitive coping strategies, goal adjustment, and depressive symptoms by the Cognitive Emotion Regulation Questionnaire, the Goal Obstruction Questionnaire, and the Hospital Anxiety and Depression Scale, respectively. Main statistical methods were Pearson correlations and multiple regression analyses. Results show significant associations among the cognitive coping strategies of rumination, catastrophizing, and higher depressive symptoms, as well as among positive refocusing, goal reengagement, and lower depressive symptoms. This suggests that cognitive coping and goal reengagement strategies may be useful targets for intervention. 相似文献
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25.
Ramin Bagheri Nejad Ramak Yahyaraeyat Ali Es‐haghi Bahar Nayeri Fasaei Taghi Zahraei Salehi 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2019,127(12):797-804
Brucellosis is a worldwide bacterial zoonosis caused by Brucella spp. No approved vaccine is available for human use against the disease. In this study, outer membrane vesicles (OMVs) from a Brucella melitensis biovar 1 human isolate obtained in Iran were used to immunize BALB/c mice (n = 12) by 2 intramuscular injections with a 2‐week interval. Another group of 12 mice was used as non‐vaccinated controls. Two weeks after the last vaccination, six mice of each group were sacrificed, and proliferation and interferon gamma (IFNγ) production responses of their splenocytes were evaluated following in vitro stimulation with killed Brucella cells. The other mice were challenged with the virulent B. melitensis isolate. Two weeks later, mice were killed and spleens were cultured to determine the number of the challenge strain. The results showed proliferative response and IFNγ production of splenocytes from vaccinated mice (stimulation index: 2.18 ± 0.57, and 1519.35 ± 10.70 pg/mL, respectively) were significantly higher than those of control mice (stimulation index: 1.02 ± 0.02, and 210.01 ± 17.58 pg/mL, respectively). Numbers of the challenge strain in spleens of vaccinated mice were also significantly less than those in the controls with 1.6 units of protection. Our study revealed vaccination with OMVs of the B. melitensis isolate could induce specific immune responses and protection against infection in the mouse model suggesting their potential application for active immunization against brucellosis. 相似文献
26.
Gerhard Koendert Pieter Bittermann Robert J.J. van Es Adrianus P. de Ruiter Arnold J.N. Bittermann Ron Koole Antoine J.W.P. Rosenberg 《Journal of cranio-maxillo-facial surgery》2021,49(2):110-117
Evaluation of relevant clinical outcomes in patients with bilateral cleft lip and palate (BCLP) after secondary aveolar bone grafting (SABG) and premaxilla osteotomy (PMO), through the use of a new scoring system.Data were collected retrospectively from all patients with BCLP who were operated on between 2004 and 2014, at the end of follow-up. The treatment protocol consisted of SABG + PMO in patients aged between 9 and 13 years. At the end of follow-up, the following parameters were scored: (un)interrupted dental arch, skeletal sagittal relationship, bone height using the Bergland/Abyholm criteria, and the presence of postoperative fistula. These parameters were combined to produce a dento-maxillary scoring system, giving a final score between 1 and 10. For statistical analysis, the independent t-test was used.Of 55 children, 45 were suitable for analysis. The mean age at time of surgery was 12.0 years (8.9–16.4 yrs), and the mean follow-up time was 11.7 years (5.8–15.8 yrs). The average number of surgeries executed under general anesthesia was 6 (range: 3–11). The average dento-maxillary score in this patient cohort was 7.6 (1–10; median: 8). Among these patients, 31 had an uninterrupted dental arch; the average Bergland/Abyholm score was 2.07; 30 patients exhibited an Angle class I incisor relationship; and, in 38 cases, the oronasal communication was closed after SABG + PMO treatment. A significant effect of fistulas was seen on dento-maxillary score (p = 0.001). Specifically, a significant effect of fistulas was seen on interrupted dental arch (p = 0.002) and on Bergland/Abyholm score (p = 0.037).The proposed dento-maxillary scoring system is a straightforward tool that can be used to describe and analyze the amount of dento-maxillary rehabilitation at the end of the treatment. Persistence of oronasal fistulas in patients with BCLP has a significant impact on interruption of the dental arch, and can influence dental results at the end of the second decade. 相似文献
27.
28.
Robert H. Kauffmann M.D. Jaap De Graeff M.D. Guy Brutel De La Rivire M.D. Leendert A. Van Es M.D. 《The American journal of medicine》1976,60(7):1048-1054
A case of the nephrotic syndrome with unilateral renal vein thrombosis is reported. The patient, an 18 year old man, presented with a six month history of edema and the recent development of a left-sided varicocele. An enlarged left kidney and a thrombus in the left renal vein were demonstrated roentgenographically. A biopsy specimen of the right kidney was interpreted as membranous glomerulonephritis. Selective renal function studies showed nearly identical creatinine excretion, and similar total protein excretion and protein selectivity from each kidney. Thus, the thrombus in the left renal vein did not influence glomerular filtration rate or quantitative or qualitative protein excretion. A high urinary output and a decreased serum level of antithrombin III were measured. These findings suggest a mechanism to explain the increased thrombotic tendency seen in this and other patients with the nephrotic syndrome. 相似文献
29.
A. J. G. Swaak A. Hannema C. Vogelaar F. A. Boom L. van Es R. van Aalst L. W. Statius van Eps 《Rheumatology international》1982,2(4):161-166
Summary Measurement of complement components in serum may not accurately assess the degree of activation of the complement system. An alternative approach is the measurement of conversion products of the complement components. The relation between the presence of an increased concentration of C3-conversion products and the metabolism of C3 was investigated. In a group of patients, circulating immune complexes were also measured (Clq-binding test) to see whether the combination of those markers yielded information on the C3 metabolism. In this study it is shown that static measurements of serum C3 levels is of no value for the degree of complement activation. Measurement of C3-conversion products may indicate C3 hypercatabolism (in 8 of the 11 patients with C3-conversion products), but it does not imply depressed C3 synthesis. Detection of circulating immune complexes by the Clq-binding assay did not always indicate a C3 hypercatabolism. Of 12 SLE patients studied, in 9 of them, a C3 hypercatabolism was detected, and 5 of these patients were clinically characterized by the presence of minor disease symptoms. Overall, the results indicated that detection of circulating immune complexes and/or C3-conversion products could not be used as an absolute measure for insight into the C3 metabolism. 相似文献
30.
B. Ünlü N. van Es W. Arindrarto S. M. Kiełbasa H. Mei J. Westerga S. Middeldorp P. J. K. Kuppen J.M.M.B. Otten S. Cannegieter H. H. Versteeg 《Journal of thrombosis and haemostasis》2018,16(2):293-302
Essentials
- The underlying pathophysiological mechanisms behind cancer‐associated thrombosis are unknown.
- We compared expression profiles in tumor cells from patients with and without thrombosis.
- Tumors from patients with thrombosis showed significant differential gene expression profiles.
- Patients with thrombosis had a proinflammatory status and increased fibrin levels in the tumor.