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排序方式: 共有123条查询结果,搜索用时 15 毫秒
31.
32.
Yuichi Tabe Erito Mochiki Mitsuhiro Yanai Yoshitaka Toyomasu Hiroyuki Ando Tetsuro Ohno Hayato Yamauchi Takaharu Fukasawa Satoru Yamaguchi Soichi Tsutsumi Takayuki Asao Hiroyuki Kuwano 《International journal of colorectal disease》2010,25(1):53-61
Purpose
The mechanism for the initiation of giant migrating contractions (GMCs) associated with defecation is not well known. The aim of this study was to describe the characteristics of special propulsive contractions (SPCs), such as GMCs, during evacuation in four experimental dog models, with emphasis on denervation.Materials and methods
Twenty healthy dogs were used in this study, and they were divided into four groups, i.e., control (underwent force transducer implantation alone), denervation (underwent transection of the descending nerve fibers along the caudal mesenteric artery (CMA)), transection (underwent transection of the rectum, which corresponds to transection of the enteric nerve fibers), and denervation-plus-transection (underwent transection of the descending nerve fibers along the CMA and transection of the rectum). Colonic contractile activities were continuously recorded on a computer. Five force transducers were implanted at the serosal surfaces of the colon (C1-R). The consistency of dog feces was checked daily. The parameters of rectal relaxation (RR), defecation characteristics, and SPCs, such as motility index (MI), duration, and frequency, were measured.Results
In the control and denervation groups, GMCs were observed with evacuation, and RR occurred synchronously with the initiation of GMCs. On the other hand, in the transection and denervation-plus-transection groups, strong force contractions without RR occurred only during evacuation. The MI and duration of the transection and denervation-plus-transection groups were higher than those of other groups (p?<?0.05). The frequency of SPCs was the highest in the denervation-plus-transection group.Conclusions
In conclusion, the continuity of enteric nerves is necessary for the occurrence of GMCs and rectal relaxation (RR). 相似文献33.
Hitoshi Nakajima Erito Mochiki Aaron Zietlow Kirk Ludwig Toku Takahashi 《Journal of gastroenterology》2010,45(5):506-514
Background
The migrating motor complex (MMC) is well characterized by the appearance of gastrointestinal contractions in the interdigestive state. This study was designed to clarify the mechanisms of gastric MMC (G-MMC) and intestinal MMC (I-MMC) in conscious dogs. 相似文献34.
Erito Mochiki Mitsuhiro Yanai Yoshitaka Toyomasu Kyouichi Ogata Hiroyuki Andoh Tetsuro Ohno Ryusuke Aihara Takayuki Asao Hiroyuki Kuwano 《Surgical endoscopy》2010,24(3):631-636
Background
Endoscopic submucosal dissection (ESD) is a safe, efficacious, and minimally invasive technique for superficial gastrointestinal neoplasms. However, the procedure is long, complex, and associated with higher complication rates. To overcome such limitations, the authors devised a double endoscopic intralumenal operation (DEILO) and assessed its efficacy and safety for superficial gastric neoplasms. 相似文献35.
Background Intracorporeal suturing and knot tying are among the most difficult procedures in laparoscopic operations. An easy and inexpensive
method for intracorporeal instrumental ligation with a modified laparoscopic needle driver is presented.
Methods The needle driver developed in this study has a novel mechanism that can fix the suturing thread in a hook at the distal site
of the holder’s jaw hinge. This hook projects out from the rod only when the jaw of the holder is open. After the needle is
removed from the tissue using the grasper, the needle driver is placed under the grasper, which the surgeon manipulates by
the left hand. Then the thread is hooked on the needle driver by withdrawal of the driver with the jaw opening. The tip of
the needle driver is moved over the shaft of the grasper by keeping the thread on the hook. The thread is entwined during
a series of crossing movements of the rods of the forceps. The short tail of the suture material is gripped and tied up as
a first throw of ligation. The side edge of the jaw, used for thread cutting, is sharpened by grinding.
Results When the angle of the forceps is set at 90° in the box trainer, no difference in terms of ligation time and degree of error
is observed between the hook and conventional C-loop methods. In the case of the 30° forceps angle, the novel method is superior
to the conventional method.
Conclusion The novel needle driver provides an easy and inexpensive method for performing an intracorporeal ligation, particularly in
a case involving a sharp axis angle of the forceps. More clinical experience is necessary for evaluation of this method, but
it has potential advantages in laparoscopic operations. 相似文献
36.
Aihara R Mochiki E Ohotake S Kamiyama Y Ohono T Kuwano H Kurokawa K Suzuki K 《Surgery today》2007,37(4):325-329
We report a case of peritoneal recurrence of gastric cancer in a 58-year-old man, 12 years after curative surgery. Urinary
wall thickness was seen on follow-up computed tomography and magnetic resonance imaging scans. We performed total nephroureterectomy
and cystectomy for urinary tract cancers, but histological examination of the resected specimen revealed poorly differentiated
adenocarcinoma with severe fibrosis, resembling the gastric cancer resected 12 years earlier. Immunohistological examination
revealed human gastric mucin (45M1) and intestinal mucin (MUC2) phenotype in both the original gastric cancers and the urinary
tract cancers. Thus, we concluded that the second cancer was a peritoneal recurrence of gastric cancer with gastric and intestinal
mucin phenotypes. Although peritoneal recurrence so many years after curative gastrectomy is rare, careful long-term follow-up
should be done for all patients undergoing surgery for gastric cancer with mucin phenotype. 相似文献
37.
Mochiki E Toyomasu Y Ogata K Andoh H Ohno T Aihara R Asao T Kuwano H 《Surgical endoscopy》2008,22(9):1997-2002
Background In recent years, laparoscopic gastrectomy has been applied for the treatment of gastric cancer in Japan and Western countries.
This report describes the short- and long-term results for patients with gastric cancer who underwent laparoscopically assisted
total gastrectomy (LATG) with lymph node dissection.
Methods From September 1999 to December 2007, 20 patients underwent LATG, and 18 underwent conventional open total gastrectomy (OTG)
for upper and middle gastric cancer. The indications for LATG included depth of tumor invasion limited to the mucosa or submucosa
and absence of lymph node metastases in preoperative examinations. The LATG and OTG procedures for gastric cancer were compared
in terms of pathologic findings, operative outcome, complications, and survival.
Results No significant difference was found between LATG and OTG in terms of operation time (254 vs 248 min.), number of lymph nodes
(26 vs 35), complication rate (25% vs 17%), or 5-year cumulative survival rate (95% vs 90.9%). Differences between LATG and
OTG were found with regard to blood loss (299 vs 758 g) and postoperative hospitalization (19 vs 29 days).
Conclusion For properly selected patients, laparoscopically assisted total gastrectomy can be a curative and minimally invasive treatment
for early gastric cancer. 相似文献
38.
Ryuusuke Aihara Tetsuro Ohno Erito Mochiki Kana Saito Shinji Sakurai Atsushi Takahashi Takayuki Asao Hiroyuki Kuwano 《Surgery today》2009,39(4):349-352
A gastrointestinal stromal tumor (GIST) of the lesser omentum is extremely rare. This report presents a case of GIST of the
lesser omentum in a 22-year-old man with a history of hepatoblastoma. Computed tomography showed an abdominal mass about 30
mm in diameter adjacent to the lesser wall of the stomach. A laparotomy showed a mass of about 27 × 24 × 20 mm in diameter
originating from the lesser omentum but isolated from the stomach and the liver. Histopathology showed that the tumor was
composed of spindle-shaped tumor cells with high cellularity. Immunohistochemically, the tumor was positive for KIT and CD34.
An in-frame deletion was observed in the c-kit gene exon 11. Therefore, the tumor was diagnosed as a GIST originating from the lesser omentum. 相似文献
39.
Study of termination of postprandial gastric contractions in humans,dogs and Suncus murinus: role of motilin‐ and ghrelin‐induced strong contraction
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40.
Laparoscopic assisted distal gastrectomy for early gastric cancer: Five years' experience 总被引:33,自引:0,他引:33
BACKGROUND: Laparoscopic assisted gastrectomy is being reported increasingly as the treatment of choice for early gastric cancer. However, no reports concerning the prognosis of patients who have undergone laparoscopic assisted distal gastrectomy (LADG) for early gastric cancer or data comparing the results to those obtained after open gastric surgery are yet available. METHODS: A retrospective study was performed comparing laparoscopic assisted and open distal gastrectomies for early gastric cancer. Eighty-nine patients who underwent LADG were compared to 60 who underwent conventional open distal gastrectomy (DG) in terms of pathologic findings, operative outcome, complications, and survival. RESULTS: There were no significant differences between LADG and DG in operation time (209 vs 200 minutes), complication rate (9% vs 18%), and 5-year survival rate (98% vs 95%). There were differences between LADG and DG with regard to blood loss (237 vs 412 mL), number of lymph nodes (19 vs 25), postoperative stay (17 vs 25 days), and the duration of epidural analgesia (2 vs 4 days) ( P < .05 each). CONCLUSIONS: For properly selected patients, LADG can be a curative and minimally invasive treatment for early gastric cancer. 相似文献