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161.
(Received for publication on Dec. 17, 1997; accepted on July 7, 1998) 相似文献
162.
Naofumi Eriguchi Shigeaki Aoyagi Toshimichi Nakayama Masao Hara Takashi Miyazaki Rumiko Kutami Atsuo Jimi 《Journal of hepato-biliary-pancreatic sciences》1998,5(4):467-470
Serous cystadenocarcinoma of the pancreas is a rare entity. We report a primary tumor of the pancreas in a 56-year-old woman that was histologically indistinguishable from microcystic adenoma, but which behaved in a malignant fashion. Metastatic lesions were found in the liver at the time of the initial operation. Nine years after the initial operation, new metastatic liver nodules were found, and the histologic characteristics of these lesions were quite similar to those of the pancreatic neoplasm. This is a very rare case which may support the existence of the entity, serous cystadenocarcinoma of the pancreas. 相似文献
163.
H Yanagie A Ogata S Mitsui T Hisa T Yamase M Eriguchi 《Biomedicine & Pharmacotherapy》2006,60(7):349-352
Anticancer polyoxomolybdates have been investigated for medical application of polyoxometalates as discrete cluster anions of metal oxides. [NH3Pri]6[Mo7O24].3H2O (PM-8) has been recognized as one of significant antitumoral polyoxomolybdates. PM-8 had shown the growth suppression against several tumors, for examples, Co-4, human colon cancer, MX-1, human breast cancer, and OAT, human lung cancer. PM-8 showed the tumor growth suppression for MKN-45 human gastric cancer in tumor bearing mice. PM-8 inhibited the cell growth of AsPC-1 which depended on the dose with showing DNA ladder formation and DNA fragmentation, and positive Hoechst staining indicating apoptosis. The ratio of apoptotic cells on flow cytometry analysis were 35%, and 57% with treatment of PM-8 after 48, and 72 h, respectively. One of the anti-tumor activity of PM-8 result from the activation of apoptotic pathway. It is thought that polyoxomolybdates will be applied as a novel anti-tumor agent especially against cancers which are difficult to be treated clinically. 相似文献
164.
Takaaki Kosugi Masahiro Eriguchi Hisako Yoshida Takayuki Uemura Hikari Tasaki Fumihiro Fukata Masatoshi Nishimoto Masaru Matsui Ken-ichi Samejima Kunitoshi Iseki Shouichi Fujimoto Tsuneo Konta Toshiki Moriyama Kunihiro Yamagata Narita Ichiei Masato Kasahara Yugo Shibagaki Masahide Kondo Koichi Asahi Tsuyoshi Watanabe Kazuhiko Tsuruya 《Geriatrics & Gerontology International》2023,23(4):282-288