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91.
Günel N Coşkun U Toruner FB Sancak B Yilmaz E Cengiz O Elbeg S Uner A Ozkan S 《Current medical research and opinion》2003,19(1):47-50
PURPOSE: Tamoxifen, used in breast cancer treatment, may induce hepatic steatosis. It has been suggested that leptin, which has a relationship with body fat stores, may be involved in the pathogenesis of hepatic steatosis. In this study, we compared serum leptin levels in tamoxifen-treated patients with and without hepatic steatosis. METHODS: Thirty-four women with breast cancer receiving tamoxifen were included in the study. Serum samples were obtained from the patients before and 3 months after tamoxifen therapy. RESULTS: Increased hepatic steatosis was detected in 15 of 34 (44%) patients after 3 months of tamoxifen therapy. Serum leptin levels were found to be significantly elevated in patients with increased hepatic steatosis (37.3 +/- 17.7 to 50.5 +/- 22.4 ng/ml, p = 0.023) compared to (48.2 +/- 20.2 to 42.6 +/- 14.9 ng/ml, p > 0.05) after tamoxifen treatment. CONCLUSION: Leptin may play a role in tamoxifen-induced hepatic steatosis. The exact mechanism involved should be investigated in further studies. 相似文献
92.
Muscle herniation can be defined as protrusion of a portion of muscle through an acquired or congenital defect of enclosing fascia. Although it is usually a cosmetic problem, it can lead to local pain and tenderness after prolonged exertion. In this report, we present a case of flexor digitorum superficialis muscle herniation in a 58-year-old man. The radiographic, ultrasonographic and magnetic resonance imaging findings are described with dynamic examination, permitting demonstration of muscle herniation through the fascial defect during muscle contraction. 相似文献
93.
Joseph JV Madeb R Leung YY Patel HR Erturk E 《Hospital medicine (London, England : 1998)》2003,64(7):411-415
Urological laparoscopic techniques have received great attention in the past decade. With the development of improved laparoscopic instrumentation, approaches to kidney and prostatic diseases have been successfully performed. Laparoscopic nephrectomy and prostatectomy are discussed. Awareness of these evolving technologies is critical for all surgeons with an interest in laparoscopy. 相似文献
94.
95.
A case presentation of bilateral simultaneous Bell's palsy 总被引:2,自引:0,他引:2
Bilateral simultaneous facial paralysis is an extremely rare clinical entity. Unlike the unilateral form, bilateral facial paralysis seldom falls into Bell's category. It is most often a special finding in a symptom complex of a systemic disease; many of them are potentially life-threatening, and therefore the condition warrants urgent medical intervention. Lyme disease, Guillian-Barre syndrome, Bell's palsy, leukemia, sarcoidosis, bacterial meningitis, syphilis, leprosy, Moebius syndrome, infectious mononucleosis, and skull fracture are the most common cause of bilateral facial paralysis. Here we present a 16-year-old patient with bilateral simultaneous Bell's palsy. 相似文献
96.
Aydin S Unal D Erol H Karaman I Yilmaz Y Sengül E Bayrakli H 《International urology and nephrology》2001,32(4):699-703
Patients with erectile dysfunction, who admitted to 4 different urological centres in Turkey were evaluated in terms of aetiological
factors to establish the aetiology of erectile dysfunction in our population and compare it with the data derived from Western
communities. After the history, physical examination, psychological evaluation and laboratory testing, a clinical diagnosis
was established as primarily psychogenic, organic, or mixed aetiology. Mean patient age was 43.5 years (range 17 to 69), and
9 of the patients were unmarried. Of the patients 53 had vascular risk factors, and 10 reported a history of alcohol abuse.
Eleven patients were using drugs that might interfere with the disorder. In this multicentral study of 115 impotent men, an
organic cause was found in 43%, psychogenic in 47%, and mixed in 19%. Mean age of the overall patients was 43.48. When the
ages of the patients with organic erectile dysfunction and those with psychogenic erectile dysfunction were compared, it was
clearly seen that those with organic erectile dysfunction were much older (52.73 versus 33.02).
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
97.
Cayan S Doruk E Bozlu M Duce MN Ulusoy E Akbay E 《International urology and nephrology》2001,33(3):513-516
Objective: Nocturnal enuresis and constipation are common pediatric problems. The aim of this study was to assess the incidence of constipation in children with or without monosymptomatic primary nocturnal enuresis.Methods: The study included 5350 children, ages 5–19 years, who were surveyed to detect the incidence of nocturnal enuresis. Of those surveyed, 679 (12.7%) had primary nocturnal enuresis. All children were questioned by mail with a standard form that addressed their micturition and defecation habits. The children those who had primary nocturnal enuresis were invited to the Pediatric Urology Section of the University Hospital. Of those 679 children, 125 kept that invitation. All 125 of those children underwent an abdominal ultrasound. Also, these children had serum creatinine levels drawn and plain abdominal films taken.Results: Constipation, defined as less than 3 bowel movements per week, was seen in 48 of 679 children with nocturnal enuresis (7.06%). Of those 4671 children without nocturnal enuresis, only 68 (1.45%) had constipation. The difference in constipation between the two groups was statistically significant (z = –9.251; p = 0.000). Of note, 10 of the 125 children (8%), evaluated at the hospital, had constipation. None of the children had an abnormal neurologic examination. Finally, faecal loading was detected on the plain films of 8 of the 125 children evaluated, 7 of who had constipation. The sensitivity of grading plain films for faecal loading to denote constipation in this population was 87.5%.Conclusions: Children with primary nocturnal enuresis should be thoroughly assessed for coexisting constipation. 相似文献
98.
99.
Ahmet Baltalarli M.D. Erdal Coşkun M.D. Melih Hulusi Us M.D. Oya Rendeci M.D. Ragıp Ortaç M.D. Bekir Hayrettin Şirin M.D. 《The International journal of angiology》2000,9(3):183-187
The neuroprotective effect of trimetazidine (TMZ) on ischemic-reperfusion injury was tested by randomized, controlled, prospective study in a rat model of transient global cerebral ischemia. Thirty wistar albino rats were used for study. Animals in TMZ group (n=10) received trimetazidine (3 mg/kg IV bolus) before the occlusion of carotid arteries. A similar volume of saline solution was used in the control group (n=10). The sham group (n=10) were anaesthetized and subjected to operative dissections without vascular occlusion. Physiological parameters, somatosensory evoked potentials (SEP's) were monitored. The neurological outcomes had been clinically evaluated and scored up to 4 days post ischemia. The intergroup differences were compared. Histological observations were clearly correlated with the neurological findings. The percentage of damaged neurons in CA1 and CA3 in subfield of hypochampus 34±6% and 16±6% in the TMZ group, whereas it was 44±5% and 24±5% in the control group (p<0.05). The average neurologic score was significantly better in animals which received TMZ than in the controls at postoperative 24 hours (17.9±1.4 in the TMZ group and 14.9±1.6 in the control group, p<0.05). The results suggest that trimetazidine reduces cerebral injury and preserves neurological function in transient global ischemia in rats.The study was carried out in the Pamukkale University Research Laboratory and Department of Cardiovascular Surgery of Faculty of Medicine, Pamukkale University, Denizli, Turkey. 相似文献
100.
Ilker Abdullah Sarikaya Ali Seker Ozan Ali Erdal Mehmet Ali Talmac Muharrem Inan 《Acta orthopaedica et traumatologica turcica》2018,52(3):174-178