全文获取类型
收费全文 | 1189篇 |
免费 | 57篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 6篇 |
儿科学 | 44篇 |
妇产科学 | 36篇 |
基础医学 | 131篇 |
口腔科学 | 17篇 |
临床医学 | 118篇 |
内科学 | 277篇 |
皮肤病学 | 37篇 |
神经病学 | 50篇 |
特种医学 | 26篇 |
外科学 | 166篇 |
综合类 | 18篇 |
一般理论 | 1篇 |
预防医学 | 93篇 |
眼科学 | 23篇 |
药学 | 97篇 |
中国医学 | 26篇 |
肿瘤学 | 85篇 |
出版年
2023年 | 3篇 |
2022年 | 19篇 |
2021年 | 32篇 |
2020年 | 16篇 |
2019年 | 25篇 |
2018年 | 32篇 |
2017年 | 31篇 |
2016年 | 19篇 |
2015年 | 31篇 |
2014年 | 51篇 |
2013年 | 58篇 |
2012年 | 113篇 |
2011年 | 97篇 |
2010年 | 68篇 |
2009年 | 46篇 |
2008年 | 73篇 |
2007年 | 65篇 |
2006年 | 81篇 |
2005年 | 49篇 |
2004年 | 46篇 |
2003年 | 37篇 |
2002年 | 30篇 |
2001年 | 25篇 |
2000年 | 14篇 |
1999年 | 10篇 |
1998年 | 12篇 |
1997年 | 5篇 |
1996年 | 5篇 |
1992年 | 8篇 |
1991年 | 7篇 |
1990年 | 8篇 |
1989年 | 6篇 |
1988年 | 4篇 |
1987年 | 5篇 |
1986年 | 11篇 |
1985年 | 5篇 |
1984年 | 13篇 |
1983年 | 10篇 |
1982年 | 11篇 |
1981年 | 10篇 |
1980年 | 5篇 |
1979年 | 8篇 |
1978年 | 4篇 |
1977年 | 3篇 |
1976年 | 4篇 |
1973年 | 3篇 |
1971年 | 10篇 |
1970年 | 4篇 |
1969年 | 3篇 |
1966年 | 2篇 |
排序方式: 共有1251条查询结果,搜索用时 0 毫秒
71.
Presence of an associated azygos lobe may cause problems during thoracotomy on the right side for esophageal atresia. Awareness of the anomaly allows its recognition and appropriate management. 相似文献
72.
73.
74.
75.
Manyam BV 《Parkinsonism & related disorders》2005,11(2):73-80
Bilateral almost symmetric calcification involving striatum, pallidum with or without deposits in dentate nucleus, thalamus and white matter is reported from asymptomatic individuals to a variety of neurological conditions including autosomal dominant inheritance to pseudo-pseudohypoparathyroidism. While bilateral striopallidodentate calcinosis is commonly referred to as 'Fahr's disease' (a misnomer), there are 35 additional names used in the literature for the same condition. Secondary bilateral calcification is also reported in a variety of genetic, developmental, metabolic, infectious and other conditions. In autosomal dominant or sporadic bilateral striopallidodentate calcinosis no known calcium metabolism abnormalities are known to date. Clinically, parkinsonism or other movement disorders appear to be the most common presentation, followed by cognitive impairment and ataxia. When presence of movement disorder, cognitive impairment and ataxia are present, a computed tomography scan of the head should be considered to rule-in or rule-out calcium deposits. Calcium and other mineral deposits cannot be linked to a single chromosomal locus. Further genetic studies to identify the chromosomal locus for the disease are in progress. 相似文献
76.
77.
78.
79.
80.
Balaña C López-Pousa A Berrocal A Yaya-Tur R Herrero A García JL Martín-Broto J Benavides M Cerdá-Nicolás M Ballester R Balart J Capellades J 《Journal of neuro-oncology》2004,70(3):359-370
This phase II study evaluates the activity of temozolomide and cisplatin administered before radiation therapy in newly diagnosed glioblastoma multiforme patients, in terms of response, time to progression and survival.Patients and methods: Forty patients with measurable disease after surgery, a Karnofsky status> 60, and Barthel Index> 10 were included. They were treated with three cycles of temozolomide 200 mg/m2/day for 5 days and cisplatin 100 mg/m2 on day 1. Conventional focal radiation therapy to 60 Gy was administered after response evaluation.Results: Three patients were not evaluable for central reviewed response but all 40 were evaluable for toxicity, time to progression and survival. Objective responses by Macdonald criteria on an intent to treat basis were 45% including complete response in three patients (7.5%), and partial response in 15 patients (37.5%). Responses were seen in biopsy-only patients (33.4%) as well as in partial surgery patients (52%). Median survival for all patients was 12.5 months. Biopsy-only patients had a median survival of 12.8 months. Grade 3 to 4 neutropenia was the most important toxicity, and occurred in 37.5% of patients. A delay in 18.2% and a dose reduction in 9.6% of cycles were necessary due to myelosuppression on day 28. Two patients had neutropenic fever resulting in one treatment-related death. Eighty-two percent of patients received radiotherapy.Conclusion: This regimen has significant activity, as it induces objective responses even in biopsy-only patients, appearing to improve their median survival. A better combination schedule is needed to improve the toxicity profile. 相似文献