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81.
Mario CRISCUOLO Jacqueline VALERIO Maria Elena GIANICOLO Emilio A.L GIANICOLO Maurizio PORTALURI 《Industrial health》2014,52(1):66-70
Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1%
of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and
the pathologist. Data on the patient’s occupational history was collected and analyzed.
The bibliographic data was found on the PUBMED bibliographic search site after entering
the word “extrahepaticangiosarcoma”. We report a case of adrenal epithelioidangiosarcoma
(AEA) in a 68 yr-old Caucasian male factory worker exposed to Vinyl Chloride (VC) for
15 yr. He underwent surgery, chemotherapy and radiotherapy. Hepatic angiosarcoma is a
known consequence of VC exposure, but occupational causality of extra-hepatic angiosarcoma
is controversial. Extra-hepatic angiosarcomas have been reported in VC workers, but never
AEA. Cancerogenic effects of VC involve all endothelial areas of the body and
extra-hepatic endothelial tumors may also be caused by this substance. This is the first
published report of AEA diagnosed in a worker exposed to VC. 相似文献
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Mario Musella Marco Milone Marcello Bellini Miguel Emilio Sosa Fernandez Loredana Maria Sosa Fernandez Maddalena Leongito Francesco Milone 《Obesity surgery》2011,21(4):426-430
The prevalence of people who are overweight or obese has increased dramatically in high-income countries over the past 20 years.
There is a strong association between obesity and infertility, and weight loss can result in increased fecundity in obese
women. The aim of this study is to demonstrate the potential role of intragastric balloon in the treatment of obese-related
infertility. This is a retrospective study. A chart review of 27 obese women seen between September 2003 and July 2008 was
performed. They all presented with the diagnosis of infertility and had undergone endoscopic intragastric balloon positioning.
Among these women who tried unsuccessfully to become pregnant before weight loss, 15 became pregnant afterward. The pregnancies
proceeded without complications and ended with live births. An improvement in the fertility status after weight loss has been
described, although data on fertility after weight loss following bariatric surgery are still limited. The results obtained
in our experience are not different from data reported in literature for bariatric surgery. Therefore, balloon treatment might
be effective in young infertile obese women who wish to become pregnant. 相似文献
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Gianelli U Cerri A Cassani B Moneghini L Raviele PR Berti E Bosari S 《Haematologica》2004,89(5):624-626
We analyzed mutations in the 5' non-coding region of the BCL-6 gene in 46 cases of primary cutaneous B-cell lymphomas (PCBCL), using a polymerase chain reaction single strand conformation polymorphism (PCR-SSCP) method. The results indicate that PCBCL display a low frequency of mutations and support a marginal zone B-cell origin for most of these neoplasms. 相似文献
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Russo Vincenzo Bottino Roberta D’Andrea Antonello Silverio Angelo Di Maio Marco Golino Paolo Nigro Gerardo Valsecchi Orazio Attena Emilio Canonico Mario Enrico Galasso Gennaro Parodi Guido Scudiero Fernando 《Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy》2022,36(4):705-712
Cardiovascular Drugs and Therapy - The clinical course of COVID-19 may be complicated by acute respiratory distress syndrome (ARDS) and thromboembolic events, which are associated with high risk of... 相似文献
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Carmona L Gómez-Reino JJ Rodríguez-Valverde V Montero D Pascual-Gómez E Mola EM Carreño L Figueroa M;BIOBADASER Group 《Arthritis and rheumatism》2005,52(6):1766-1772
OBJECTIVE: To investigate the impact of official recommendations regarding the management of latent tuberculosis (TB) infection on the rate of active TB in patients receiving treatment with tumor necrosis factor (TNF) antagonists. METHODS: Data on active TB rates and on screening and treatment of latent TB infection were extracted from the BIOBADASER (Spanish Society of Rheumatology Database on Biologic Products), a registry of patients with rheumatic conditions treated with TNF antagonists. The rates of active TB among the BIOBADASER patients were compared with those in the background Spanish population, and BIOBADASER patients with rheumatoid arthritis (RA) were compared with a cohort of RA patients from the EMECAR (Morbidity and Clinical Expression of Rheumatoid Arthritis) study who were not treated with TNF antagonists and were followed up for 5 years. RESULTS: Active TB developed in 34 patients, of whom 32 started taking TNF antagonists prior to the official recommendations on latent TB infection (pre-OR) and 2 began treatment after the recommendations were issued (post-OR). All cases of TB occurred during treatment with infliximab, and 28 of these patients had RA. Pre-OR, the active TB rate in BIOBADASER patients was 20.9-fold higher than in the background Spanish population, while RA patients in the BIOBADASER had rates 22.6- and 6.2-fold higher than the background and EMECAR populations, respectively. Post-OR, 324 patients with a tuberculin skin test result > or =5 mm and/or chest radiograph findings suggestive of past TB were treated for 9 months with isoniazid (INH). Post-OR, active TB rates among the BIOBADASER patients decreased by 78% (incidence risk ratio [IRR] 0.22, 95% confidence interval [95% CI] 0.03-0.88; P = 0.008), while among RA patients in the BIOBADASER, the rate dropped by 83% and reached the EMECAR rate (IRR 1.0, 95% CI 0.02-8.2). There were no INH treatment-related hospitalizations or deaths. CONCLUSION: Strategies to treat latent TB infection that are tailored to the at-risk population can effectively and safely lessen the likelihood of active TB in patients treated with TNF antagonists. 相似文献