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排序方式: 共有1886条查询结果,搜索用时 31 毫秒
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Nguyen Van Hong Alfred Amambua-Ngwa Nguyen Quang Tuan Do Duy Cuong Nguyen Thi Huong Giang Nguyen Van Dung Ta Thi Tinh Nguyen Van Tien Bui Quang Phuc Tran Thanh Duong Anna Rosanas-Urgell Umberto D’Alessandro Jean-Pierre Van Geertruyden Annette Erhart 《Emerging infectious diseases》2014,20(7):1207-1210
Resistance to artemisinin derivatives, the most potent antimalarial drugs currently used, has emerged in Southeast Asia and threatens to spread to Africa. We report a case of malaria in a man who returned to Vietnam after 3 years in Angola that did not respond to intravenous artesunate and clindamycin or an oral artemisinin-based combination. 相似文献
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James W. Harrison Tran Thi Ngoc Dung Fariha Siddiqui Sunee Korbrisate Habib Bukhari My Phan Vu Tra Nguyen Van Minh Hoang Juan Carrique-Mas Juliet Bryant James I. Campbell David J. Studholme Brendan W. Wren Stephen Baker Richard W. Titball Olivia L. Champion 《Emerging infectious diseases》2014,20(6):1026-1029
A novel protein translocation system, the type-6 secretion system (T6SS), may play a role in virulence of Campylobacter jejuni. We investigated 181 C. jejuni isolates from humans, chickens, and environmental sources in Vietnam, Thailand, Pakistan, and the United Kingdom for T6SS. The marker was most prevalent in human and chicken isolates from Vietnam. 相似文献
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Thierry Poynard Valentina Peta Olivier Deckmyn Mona Munteanu Joseph Moussalli Yen Ngo Marika Rudler Pascal Lebray Raluca Pais Luminita Bonyhay Frederic Charlotte Vincent Thibault Laetitia Fartoux Olivier Lucidarme Daniel Eyraud Olivier Scatton Eric Savier Marc Antoine Valantin An Ngo Fabienne Drane Olivier Rosmorduc Franoise Imbert‐Bismut Chantal Housset Dominique Thabut Vlad Ratziu 《Alimentary pharmacology & therapeutics》2019,49(3):308-320
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Ibrahim Aldoss Jianying Zhang Matthew Mei Monzr M Al Malki Shukaib Arslan Dat Ngo Ahmed Aribi Haris Ali Karamjeet Sandhu Amandeep Salhotra Paul Koller Samer Khaled Andrew Artz David Snyder Ryotaro Nakamura Stephen J Forman Anthony S. Stein Guido Marcucci Vinod Pullarkat 《American journal of hematology》2020,95(10):1193-1199
FMS-like tyrosine kinase 3 (FLT3) mutations are prevalent in acute myeloid leukemia (AML), and their presence confers adverse risk. FLT3-mutated (FLT3m) AML is a challenging leukemia to manage, particularly in older and unfit patients as well as patients with relapsed/refractory (r/r) disease. We retrospectively analyzed the outcomes of 50 FLT3m AML patients (17 treatment-naïve, 33 r/r) treated with venetoclax (VEN) and hypomethylating agents (HMA). The overall CR/CRi rate with VEN-HMA was 60% (94% in treatment-naïve AML and 42% in r/r AML). Early (60-days) treatment related mortality was 2%. The r/r AML setting was an independent predictor of lower complete response (OR: 0.08; 95%CI: 0.00-0.60, P = .03). Cytogenetics-molecular risk, concurrent mutations, the type of FLT3 mutation (ITD vs TKD), the ITD allelic ratio, the type of HMA, age, prior exposure to HMA and receipt of prior allogeneic transplant did not independently impact response or leukemia-free survival (LFS). Concurrent IDH mutations were associated with lower CR/CRi (P = .01), while ASXL1 or TET2 mutations showed a non-significant association toward higher CR/CRi (P = .07, for both). However, none of the concurrent mutations were an independent predictor for response when adjusted to AML setting. In conclusion, VEN-HMA is associated with encouraging efficacy in FLT3m AML among both newly diagnosed unfit and r/r patients. 相似文献
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T. M. L. Huynh B. H. Nguyen V. G. Nguyen H. A. Dang T. N. Mai T. H. G. Tran M. H. Ngo V. T. Le T. N. Vu T. K. C. Ta V. H. Vo H. K. Kim B. K. Park 《Transboundary and Emerging Diseases》2014,61(6):e25-e34
This study demonstrated the prevalence of Porcine circovirus type 2 (PCV2) among pig farms in Vietnam. Analyses of the genome, capsid protein and phylogeny classified all 30 Vietnamese PCV2 strains as the PCV2b genotype, belonging to the clusters of 1A, 1B, 1C and recombinant forms. Each viral genome was 1767 nucleotides long and shared 96.0–100% nucleotide sequence identity. The amino acid substitutions in the capsid protein of the Vietnamese PCV2 strains were in immunodominant regions, and the majority of strains (24/30) contained a lysine extension at the C‐terminus. Bayesian phylogeographic analysis revealed epidemic links of the PCV2 recombinant cluster within and among countries, which supports a circulating recombinant form of PCV2. Further analysis by the Jameson–Wolf antigenic index indicated antigenic alterations at important sites in the capsid protein (sites 131–133) among the recombinant cluster and the other clusters of PCV2b. 相似文献
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Camille Nicolas Vincent Vuiblet Veronique Baudouin Marie-Alice Macher Isabele Vrillon Nathalie Biebuyck-Gouge Maud Dehennault Sophie Gié Denis Morin Hubert Nivet François Nobili Tim Ulinski Bruno Ranchin Maria Chiarra Marinozzi Stéphanie Ngo Véronique Frémeaux-Bacchi Christine Pietrement 《Pediatric nephrology (Berlin, Germany)》2014,29(1):85-94