首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   250篇
  免费   10篇
  国内免费   4篇
耳鼻咽喉   1篇
妇产科学   1篇
基础医学   17篇
口腔科学   8篇
临床医学   37篇
内科学   73篇
皮肤病学   6篇
神经病学   28篇
特种医学   5篇
外科学   59篇
综合类   1篇
预防医学   7篇
药学   13篇
肿瘤学   8篇
  2023年   6篇
  2022年   12篇
  2021年   22篇
  2020年   4篇
  2019年   16篇
  2018年   14篇
  2017年   4篇
  2016年   9篇
  2015年   13篇
  2014年   9篇
  2013年   7篇
  2012年   21篇
  2011年   26篇
  2010年   12篇
  2009年   16篇
  2008年   17篇
  2007年   9篇
  2006年   13篇
  2005年   8篇
  2004年   10篇
  2003年   8篇
  2002年   3篇
  2001年   1篇
  2000年   1篇
  1999年   2篇
  1997年   1篇
排序方式: 共有264条查询结果,搜索用时 15 毫秒
101.

Introduction

Surgical management of proximal humerus fractures remains controversial and there is an increasing interest in intramedullary nailing. Created to improve previous designs, the T2-proximal humeral nail (PHN) (Stryker®) has been recently released, and the English literature lacks a series evaluating its results. We present a clinical prospective study evaluating this implant for proximal humeral fractures.

Method

We evaluated the functional and radiological results and possible complications. Twenty-nine patients with displaced fractures of the proximal humerus were treated with this nail. One patient was lost right after surgery and excluded from the assessment. Eighteen patients were older than 70 years.

Results

There were 21 fractures of the proximal part of the humerus and 7 fractures that also involved the shaft; 15 of the fractures were two-part fractures (surgical neck), 5 were three-part fractures, and 1 was a four-part fracture. All fractures healed in a mean period of 2.7 months. There was one delayed union that healed in 4 months. One case of avascular necrosis of the humeral head was observed (a four-part fracture), but remained asymptomatic and did not require further treatment. In one case a back-out of one proximal screw was observed. A final evaluation with a minimum 1 year follow-up was performed by an independent observer; in 18 patients, the mean Constant score was 65.7 or 76.1% with the adjustment of age and gender; in 19 patients, the mean Oxford Shoulder Score was 21.7. The results obtained with the T2-PHN nail indicate that it represents a safe and reliable method in the treatment of two- and three-part fractures of the proximal humerus. The proximal fixation mechanism diminishes the rate of back-out of the screws, a frequent complication described in the literature. Better functional results were obtained from the patients younger than 70 years, but these were not statistically significant.
  相似文献   
102.
BackgroundAbsent end-diastolic flow (AEDF) in the umbilical artery (UA) worsens the already poor prognosis of growth-restricted fetuses (GRFs) in pregnancies complicated by early-onset preeclampsia with severe features (ESP).MethodWe assessed the correlation between the effect of maternal dexamethasone (Dex) on AEDF in the UA and perinatal outcomes, in 59 GRFs from EPS-complicated pregnancies. The maternal outcome was also evaluated.ResultsThe mean maternal age at inclusion was 22.4 ± 5.9 years. Dex transiently restored EDF in the UA in 38 (64.4%) cases (trAEDF group), but in 21 (35.6%) patients, the flow was persistently absent (prAEDF group). The effect lasted up to the 4th day.The gestational age at diagnosis, number of days from admission until delivery, and fetal weight were significantly lower in the prAEDF group than in the trAEDF group (p < .05). The same group had a significantly increased rate of fetal proximal deterioration, low APGAR scores, neonatal hypoxia, assisted ventilation, mild intraventricular haemorrhage (I/II), and respiratory distress syndrome, as well as maternal deterioration, especially in cases of resistant hypertension (p < .05). Although the rates of fetal acidemia and perinatal mortality in the prAEDF group were respectively three times and two times higher, the differences were not significant (p > .05).ConclusionsThe Dex no-effect on UA Doppler in GRFs with AEDF in the UA, in EPS-complicated pregnancies, can be a useful marker for a higher risk of proximal fetal deterioration, poor state at delivery, neonatal hypoxic complications, and worsening maternal condition, but not for perinatal mortality. The findings also highlight the alarmingly younger age of patients with EPS. Finally, all these pregnancies should be monitored in a complex multidisciplinary manner in tertiary referral units.

Key message

  • The effect of dexamethasone on absent end-diastolic flow in the umbilical artery in growth-restricted fetuses from pregnancies complicated by early-onset preeclampsia with severe features can be a useful prognostic factor for perinatal outcomes.
  相似文献   
103.
Purpose  Assessment of volume in relation with left atrial (LA) shape alteration before and after PV isolation. Methods  We compared trapezoidal modification of LA using echocardiography with the ellipsoid formula (Eel) and CT, with both ellipsoid (CTel) and truncated cone formulas (CTtr), in 40 patients, before and ±3 months after AF ablation. Results  A trapezoidal shape was present in 76.3% of patients. The different volume measurements were statistically correlated (r = 0.603–0.837, p < 0.001) irrespective of the formula used. After reverse remodeling, with 77.5% of patients in stable sinus rhythm, correlation coefficient for volume remained significant (p < 0.001). Conclusions  In AF, dilation of the LA is associated with a geometrical trapezoidal change in many cases. The CT truncated cone formula applies best for precise evaluation of trapezoidal shape alteration in dilated AF atria. There is a good correlation between CTtr and echocardiography which remains a valuable estimation for volume calculation in clinical practice. The authors have no disclosures related to the present work.  相似文献   
104.
To assess subendocardial (long-axis) and mid-wall (short-axis) left ventricular (LV) function in patients with type 1 myotonic dystrophy (MD1), with no symptoms or clinical signs of heart disease, to investigate if they have subclinical cardiac involvement, 28 subjects (14 with MD1, and 14 age- and sex-matched normals) had conventional and tissue Doppler echocardiography. Myocardial velocities and timings to peak systolic contractions were measured. LV wall thickness, diameters, and ejection fraction were not different between the groups. 4/14 of the MD1 patients (29%) had global diastolic dysfunction. Both long-axis and short-axis systolic and early diastolic myocardial velocities were lower in patients with MD1, whereas time-to-peak myocardial contraction was longer; mean longitudinal systolic velocity was 5.5+/-1.7 cm/s in patients with MD1, compared with 7.8+/-1.3 cm/s in normal subjects (P<0.001) 10/14 of the patients (71%) had reduced longitudinal systolic function. Longitudinal systolic and diastolic velocities were inversely related to the duration of the QRS complex ( r=-0.86 and r=-0.63 respectively, both P<0.01), but they did not correlate with the CTG-repeat size. Patients with MD1 have subclinical cardiac impairment revealed by measurement of myocardial velocities using tissue Doppler echocardiography.  相似文献   
105.
We report the case of a 59-year-old male patient who returned to the Hospital with severe pain in the right upper arm, 9 hours after reduction of an anterior dislocation of the right shoulder. A thrombosis of the axillary artery was quickly diagnosed and the rapid treatment allowed revascularisation in the arm without any major consequences.  相似文献   
106.
107.

Background

There is no clear consensus on the treatment of partial articular-sided supraspinatus tendon avulsions. Debridement alone might not be sufficient to prevent further tendon degradation or alleviate patient complaints. Direct repair using a suture anchor without treating the concomitant conditions of the long head of the biceps tendon might come with residual anterior shoulder pain or even further loss of function in cases of failed repair. The purpose of the present study is to describe an arthroscopic technique by which the long head of the biceps tendon can be included in the partial articular-sided supraspinatus tendon avulsion repair.

Technique Presentation with video

In this technical note we describe the arthroscopic repair and augmentation with tenotomized biceps of partial supraspinatus tendon tears to address three main concepts for successful rotator cuff repairs, namely rotator cuff biologic augmentation, tendon to bone healing and postoperative pain prevention.

Conclusion

The biceps tendon is a mechanically robust, locally available autograft that can be used in borderline partial articular-sided supraspinatus tendon avulsions in order to biologically augment healing at the tendon-bone interface without any immunogenic reactions or morbidity following harvesting.  相似文献   
108.
109.
Starting from methyl methacrylate (MMA), butyl methacrylate (BMA), allyl methacrylate (AMA), phenoxycarbonyloxy ethyl methacrylate (PCEMA), and functional amines different multifunctional polymethacrylates are accessible. The reactive monomer PCEMA was synthesized starting from 2‐hydroxyethyl methacrylate, and then copolymerized via ATRP with other methacrylates in order to obtain reactive copolymers which were subjected to polymer analogous reactions with different functional amines leading to multifunctional polymethacrylates. These can be used for the preparation of multifunctional surfaces.

  相似文献   

110.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号