全文获取类型
收费全文 | 33361篇 |
免费 | 2414篇 |
国内免费 | 1029篇 |
专业分类
耳鼻咽喉 | 356篇 |
儿科学 | 416篇 |
妇产科学 | 372篇 |
基础医学 | 5166篇 |
口腔科学 | 514篇 |
临床医学 | 3444篇 |
内科学 | 5444篇 |
皮肤病学 | 804篇 |
神经病学 | 2397篇 |
特种医学 | 1606篇 |
外国民族医学 | 5篇 |
外科学 | 3813篇 |
综合类 | 2498篇 |
现状与发展 | 7篇 |
一般理论 | 9篇 |
预防医学 | 1855篇 |
眼科学 | 856篇 |
药学 | 3456篇 |
15篇 | |
中国医学 | 1063篇 |
肿瘤学 | 2708篇 |
出版年
2024年 | 60篇 |
2023年 | 410篇 |
2022年 | 1095篇 |
2021年 | 1511篇 |
2020年 | 862篇 |
2019年 | 945篇 |
2018年 | 1073篇 |
2017年 | 854篇 |
2016年 | 1098篇 |
2015年 | 1528篇 |
2014年 | 1840篇 |
2013年 | 1998篇 |
2012年 | 2849篇 |
2011年 | 2941篇 |
2010年 | 1716篇 |
2009年 | 1429篇 |
2008年 | 2003篇 |
2007年 | 1881篇 |
2006年 | 1682篇 |
2005年 | 1588篇 |
2004年 | 1245篇 |
2003年 | 1063篇 |
2002年 | 883篇 |
2001年 | 703篇 |
2000年 | 732篇 |
1999年 | 581篇 |
1998年 | 264篇 |
1997年 | 222篇 |
1996年 | 168篇 |
1995年 | 161篇 |
1994年 | 137篇 |
1993年 | 103篇 |
1992年 | 162篇 |
1991年 | 171篇 |
1990年 | 140篇 |
1989年 | 106篇 |
1988年 | 88篇 |
1987年 | 80篇 |
1986年 | 72篇 |
1985年 | 48篇 |
1984年 | 34篇 |
1983年 | 37篇 |
1982年 | 30篇 |
1981年 | 21篇 |
1980年 | 21篇 |
1979年 | 31篇 |
1978年 | 18篇 |
1977年 | 16篇 |
1976年 | 13篇 |
1974年 | 17篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
21.
Tinghu Kang Yang Li Jiandong Guo Xingwen Ma Fatema Akhter Hiramoni Md Zahir Ahmed Mary C. Jobe Oli Ahmed 《International Journal of Mental Health Promotion, The》2022,24(2):207-217
The aim of the study was to explore the relationship between college graduates’ dual self-consciousness, job search
clarity and perceived stress, and reveal the mediating role of perceived stress between dual self-consciousness and
job search clarity. In this study, 467 college graduates were investigated using the Dual Self-Consciousness Scale,
Job Search Clarity Scale, and Perceived Stress Scale. After controlling for gender, age, and region, the results
revealed that: (1) private self-consciousness has a significant positive predictive effect on job search clarity; (2)
perceived stress has a significant negative predictive effect on job search clarity; (3) perceived stress plays partial
mediation effects between private self-consciousness and job search clarity; (4) perceived stress plays complete
mediation effects between public self-consciousness and job search clarity; (5) perceived stress has suppressing
effects between public self-consciousness and job search clarity. 相似文献
22.
23.
Thomas S. Klitzner Maggie Lee Sandra Rodriguez Ruey‐Kang R. Chang 《Congenital heart disease》2006,1(3):77-88
Background. It has been reported that gender differences in cardiovascular outcomes found in adults also are present in children who undergo surgical repair for congenital heart disease. Methods. California statewide hospital discharge data 1989–99 were used to study outcomes in children <18 years undergoing cardiac surgery. Hospital discharge data were linked to death registry data to study postdischarge death within 30 days of discharge. We used logistic regression to evaluate the effect of gender on mortality controlling for age, race and ethnicity, type of insurance, household income, date and month of surgery, type of admission, hospital case volume, and various types of procedures. Results. There were 25 402 cardiac surgery cases with 1505 in‐hospital deaths (mortality rate of 5.92%). An additional 37 deaths occurred within 30 days after hospital discharge. Crude mortality rates for males (5.99%) and females (5.84%) were not significantly different. However, fewer neonates were female and females underwent a higher proportion of low‐risk procedures than males. Logistic regression revealed that females, compared with males, had a significantly higher odds ratio (OR) for in‐hospital mortality (OR = 1.18, P < .01) and overall (up to 30 days post discharge) mortality (OR = 1.18, P < .01). The risk‐adjusted length of hospital stay was similar between females and males while charges per hospital day were slightly higher in females than males. The prevalence of Down syndrome, pulmonary hypertension, and failure to thrive were higher in females. Conclusions. Female gender is associated with an 18% higher in‐hospital and 30‐day postdischarge mortality as compared with male gender. There was no difference in length of hospital stay between males and females. The mechanism by which female gender acts as a risk factor requires further investigation. 相似文献
24.
皮质发育障碍模型的建立及其致痫敏感性的研究 总被引:1,自引:0,他引:1
目的:建立皮质发育障碍模型,探讨皮质发育障碍模型的敏感性。方法:在SD大鼠孕17d腹腔注入1,3-二氯乙烯-亚硝基脲(BCNU)制作皮质发育障碍模型;Nissl染色观察P60d仔鼠病理变化;选取P60d雄性仔鼠,腹腔注射氯化锂-毛果芸香碱,分别比较两组大鼠癫发生的潜伏期、持续状态时间和死亡率。结果:同龄仔鼠脑组织湿重实验组比对照组显著减轻(P<0.01);Nissl染色显示皮质变薄、皮质层次紊乱、海马区域异位细胞异常聚集;有皮质发育障碍的仔鼠注射氯化锂-毛果芸香碱后,癫发生的潜伏期显著缩短(P<0.01),癫持续状态时间延长(P<0.01),死亡率显著升高(P<0.05)。结论:BCNU致皮质发育障碍模型具有癫易感性。 相似文献
25.
H J Kim C H Kang Y T Kim S-W Sung J H Kim S M Lee C-G Yoo C-T Lee Y W Kim S K Han Y-S Shim J-J Yim 《The European respiratory journal》2006,28(3):576-580
Although surgical lung resection could improve prognosis in some patients with multidrug-resistant tuberculosis (MDR-TB), there are no reports on the optimal candidates for this surgery. The aim of the present study was to elucidate the prognostic factors for surgery in patients with MDR-TB. Patients who underwent lung resection for the treatment of MDR-TB between March 1993 and December 2004 were included in the present study. Treatment failure was defined as greater than or equal to two of the five cultures recorded in the final 12 months of treatment being positive, any one of the final three cultures being positive, or the patient having died during treatment. The variables that affected treatment outcomes were identified through univariate and multivariate logistic regression analysis. In total, 79 patients with MDR-TB were included in the present study. The treatment outcomes of 22 (27.8%) patients were classified as failure. A body mass index <18.5 kg x m(-2), primary resistance, resistance to ofloxacin and the presence of a cavitary lesion beyond the range of the surgical resection were associated with treatment failure. Low body mass index, primary resistance, resistance to ofloxacin and cavitary lesions beyond the range of resection are possible poor prognostic factors for surgical lung resection in multidrug-resistant tuberculosis patients. 相似文献
26.
27.
28.
Changes in outcome with sphincter preserving surgery for rectal cancer in Korea, 1991-2000. 总被引:3,自引:0,他引:3
S-B Lim S C Heo M R Lee S-B Kang Y J Park K J Park H S Choi S-Y Jeong J-G Park 《European journal of surgical oncology》2005,31(3):242-249
AIM: To report the clinical and oncological data of patients operated on for rectal cancers 3-5 cm from the AV over a 10 year period, including the Sphincter preservation (SP) rate. METHODS: We reviewed medical records of 304 patients with rectal cancers 3-5 cm from the AV who underwent surgical resection from January 1991 through December 2000. The 10 years were divided into three periods based on the introduction of new surgical techniques, specifically, ultralow anterior resection (ULAR) with double stapling in March 1994 and ULAR with coloanal anastomosis in April 1997. The rates of SP, complications and patient survival during these periods were compared. RESULTS: The SP rate increased significantly over the 10 years, from 16.4% in period I (January 1991-February 1994), to 53.0% in period II (March 1994-March 1997), to 86.5% in period III (April 1997-December 2000) (p<0.001). Over time, the age of the patients increased (p=0.004), the length of the distal resection margin became shorter (p=0.005), and the rate of lymph node metastasis increased (p=0.016). The factors significantly influencing SP were the period (p<0.001) and the distance from the AV (p<0.001). Over time, morbidity did not increase, and overall and disease free survival rates did not decrease. In contrast, the overall survival of N2 cases significantly increased over time (p=0.0492). CONCLUSION: Over 10 years, the SP rate in rectal cancers 3-5 cm from the AV was significantly increased by the introduction of the double stapling and coloanal anastomosis techniques. These surgical methods, however, had no effect on morbidity, disease free survival and overall survival rates. 相似文献
29.
本实验用~3H-TdR掺入,液体闪烁测量法测定细胞DNA期外合成的方法,测定了小鼠和大鼠的肠淋巴结细胞、人和大鼠外周血淋巴细胞、S-180V肿瘤细胞等经紫外线照射后的UDS,观察到UDS掺入量随辐照度增加而增加。在同一辐照剂量下,以小鼠肠淋巴结细胞的UDS值最高,其次是人外周血淋巴细胞和S-180V肿瘤细胞,而大鼠外周血淋巴细胞和肠淋巴结细胞最低。 相似文献
30.
目的 研究异型增生程度不同的口腔白斑和不同分级的鳞癌中谷胱苷肽S转移酶π(GST π)的表达 ,探讨GST π在口腔鳞癌发生发展中的作用。 方法 采用免疫S -P法 ,对 5 4例轻、中、重度异型增生 ,4 7例高、中、低分化的口腔鳞癌 ,7例口腔粘膜上皮单纯增生患者组织进行GST π检测。 结果 口腔粘膜上皮单纯增生组织中未见GST π的表达 ,轻、中、重度异型增生病例中的GST π阳性率分别为4 7.8%、5 2 .9%和 6 4 .2 % ,高于单纯增生组 (P <0 .0 1) ;高分化鳞癌GST π阳性率为 6 4 .7% ,中、低分化鳞癌组分别为 2 8.5 %及 2 2 .2 % ,中、低分化鳞癌组表达均低于高分化鳞癌组及异型增生组 (P <0 .0 5 )。 结论 GST π表达的变化与口腔鳞癌早期的发生发展密切相关 相似文献