全文获取类型
收费全文 | 412篇 |
免费 | 12篇 |
国内免费 | 73篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 9篇 |
妇产科学 | 13篇 |
基础医学 | 32篇 |
口腔科学 | 6篇 |
临床医学 | 82篇 |
内科学 | 97篇 |
皮肤病学 | 4篇 |
神经病学 | 25篇 |
特种医学 | 56篇 |
外科学 | 37篇 |
综合类 | 15篇 |
预防医学 | 10篇 |
眼科学 | 31篇 |
药学 | 65篇 |
肿瘤学 | 14篇 |
出版年
2024年 | 1篇 |
2023年 | 2篇 |
2022年 | 4篇 |
2021年 | 6篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 8篇 |
2017年 | 7篇 |
2016年 | 3篇 |
2015年 | 7篇 |
2014年 | 12篇 |
2013年 | 19篇 |
2012年 | 22篇 |
2011年 | 26篇 |
2010年 | 14篇 |
2009年 | 16篇 |
2008年 | 11篇 |
2007年 | 53篇 |
2006年 | 17篇 |
2005年 | 26篇 |
2004年 | 8篇 |
2003年 | 21篇 |
2002年 | 23篇 |
2001年 | 17篇 |
2000年 | 13篇 |
1999年 | 10篇 |
1998年 | 18篇 |
1997年 | 18篇 |
1996年 | 18篇 |
1995年 | 15篇 |
1994年 | 4篇 |
1993年 | 6篇 |
1992年 | 4篇 |
1991年 | 6篇 |
1990年 | 5篇 |
1989年 | 13篇 |
1988年 | 9篇 |
1987年 | 6篇 |
1986年 | 3篇 |
1985年 | 1篇 |
1984年 | 3篇 |
1983年 | 1篇 |
1980年 | 3篇 |
1978年 | 2篇 |
1977年 | 5篇 |
1976年 | 1篇 |
1975年 | 1篇 |
1973年 | 1篇 |
排序方式: 共有497条查询结果,搜索用时 0 毫秒
81.
82.
83.
84.
85.
L-carnitine is a quaternary amine that is essential for the normal oxidation of long-chain fatty acids by mitochondria. It is known that L-carnitine and its derivatives prevent the formation of reactive oxygen species, scavenge free radicals and protect cells from peroxidative stress. Oxygen-derived free radicals and lipid peroxidation products play a critical role in the pathogenesis of ethanol-induced gastric mucosal injury. The aim of the present study was to determine the effect of L-carnitine on lipid peroxidation induced by ethanol in the rat stomach. In our study, gastric mucosal injury was induced by the intragastric administration of 1 ml of absolute ethanol. Test compounds were given to rats by gavage 30 min before the ethanol administration. The animals were killed 60 min after the administration of ethanol. The stomach of each animal was removed. Mucosal damage was evaluated by macroscopic examination, histological analysis and by measurement of lipid peroxidation and glutathione activity. The intragastric administration of ethanol induced hyperemia and hemorrhagic erosions in the rat stomachs. L-carnitine significantly prevented gastric ulcerogenesis induced by ethanol and decreased the ulcer index. Plasma and gastric lipid peroxidation that was increased significantly by ethanol was decreased after treatment with L-carnitine. Ethanol treatment decreased significantly the gastric glutathione levels, and pretreatment with L-carnitine increased them significantly. Based on these data, the beneficial effects of L-carnitine on ethanol-induced gastric mucosal injury may be attributed to its antiperoxidative effects. 相似文献
86.
87.
Doganay S Karaman A Gündogdu F Duran C Yalcin A Kantarci M 《Japanese journal of radiology》2011,29(5):342-347
Purpose
Cardiac resynchronization therapy (CRT) is a treatment option for selected heart failure patients. In this study, the aim was to evaluate the usefulness of noninvasive cardiac vein imaging using multidetector computed tomography (MDCT) angiography before CRT. 相似文献88.
Objective
The aim of our study was to investigate the value of choline in the discrimination of benign and malignant soft tissue and bone tumors.Materials and methods
The study group consisted of thirty subjects with bone or soft tissue tumors larger than 1.5 cm in diameter. The experiments were performed in a 1.5 T MR scanner. Coils were selected according to specific locations. A single-voxel MRS was performed for three different TE (time to echo) (31, 136, 272 ms). The volume of interest was positioned on the brightest enhancement. The presence of a cholin peak on at least 2 of these spectrums was considered as the marker of malignancy. The sensitivity, specificity and accuracy of the MRS in the detection and diagnosis of malignant lesions were calculated. The reproducibility of MRS and histopathological results were tested with kappa statistics.Results
Histopathologically, 18 (60%) of the lesions were classed as malignant whereas 12 (40%) were classed as benign. With MRS, 15 (50%) of these lesions were classed as malignant and 15 (50%) as benign. Two patients who were found spectroscopically to have malignant tumors were shown histopathologically to have benign types. Five patients with an MRS showing a benign type were classed with malignant types in histopathological examinations. MRS had a sensitivity rate of 72.2%, specificity of 83.3%, and an accuracy rate of 76.6% in detecting malignant bone and soft tissue tumors. The interrater reliability of both techniques had a kappa value of 0.533.Conclusions
MRS may help in the differentiation of benign and malignant soft tissue and bone tumors. 相似文献89.
Poland syndrome was first described in 1840 by Alfred Poland while still a medical student and the other components of the syndrome were described at London Guy's Hospital following the dissection of a cadaver's hand, which had hypoplasia and syndactyly. The incidence of Poland syndrome has been reported to be 1 in 30,000 live births. In the present case report, two Poland syndrome patients with ipsilateral hypomastia and a reduction in the axillary/pectoral hairs diagnosed during adulthood are presented; one patient was affected on the left side and had widespread cafe au lait spots, and the other patient had respiratory dysfunction due to multiple rib anomalies. 相似文献
90.