全文获取类型
收费全文 | 150248篇 |
免费 | 14179篇 |
国内免费 | 8622篇 |
专业分类
耳鼻咽喉 | 1204篇 |
儿科学 | 2001篇 |
妇产科学 | 1666篇 |
基础医学 | 22339篇 |
口腔科学 | 2775篇 |
临床医学 | 17789篇 |
内科学 | 21537篇 |
皮肤病学 | 1796篇 |
神经病学 | 7355篇 |
特种医学 | 5348篇 |
外国民族医学 | 65篇 |
外科学 | 14676篇 |
综合类 | 23459篇 |
现状与发展 | 29篇 |
一般理论 | 12篇 |
预防医学 | 10460篇 |
眼科学 | 3624篇 |
药学 | 16976篇 |
121篇 | |
中国医学 | 7896篇 |
肿瘤学 | 11921篇 |
出版年
2024年 | 579篇 |
2023年 | 2301篇 |
2022年 | 5881篇 |
2021年 | 7537篇 |
2020年 | 5461篇 |
2019年 | 4926篇 |
2018年 | 5198篇 |
2017年 | 4747篇 |
2016年 | 4620篇 |
2015年 | 6644篇 |
2014年 | 8165篇 |
2013年 | 7968篇 |
2012年 | 11220篇 |
2011年 | 11799篇 |
2010年 | 8251篇 |
2009年 | 6598篇 |
2008年 | 8079篇 |
2007年 | 8060篇 |
2006年 | 7360篇 |
2005年 | 6663篇 |
2004年 | 5232篇 |
2003年 | 5053篇 |
2002年 | 4311篇 |
2001年 | 3536篇 |
2000年 | 3057篇 |
1999年 | 2711篇 |
1998年 | 1688篇 |
1997年 | 1804篇 |
1996年 | 1264篇 |
1995年 | 1202篇 |
1994年 | 1101篇 |
1993年 | 776篇 |
1992年 | 991篇 |
1991年 | 924篇 |
1990年 | 807篇 |
1989年 | 750篇 |
1988年 | 669篇 |
1987年 | 577篇 |
1986年 | 540篇 |
1985年 | 436篇 |
1984年 | 374篇 |
1983年 | 305篇 |
1982年 | 274篇 |
1981年 | 235篇 |
1980年 | 202篇 |
1979年 | 213篇 |
1978年 | 197篇 |
1977年 | 215篇 |
1976年 | 193篇 |
1974年 | 160篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
41.
Rapid growth in biomedical research coupled with dramatic advancement in biotechnology has significantly improved our understanding of the molecular basis involving cancer development and progression. This improvement has led to the discovery of new molecular markers for cancer diagnosis and prognosis as well as new molecular targets for cancer treatment and intervention. Continuous emergence of some new developing area in molecular profiling, new therapeutic agents, tissue microenvironment and systems biology have made significant progress in clinical oncology. Clinical research and investigation that focus on these new developments have begun to show exciting results that indicate future promises in improving patient management and survival. 相似文献
42.
The influence of chronic administration of a dry cleared extract of Glycyrrhiza glabra (DCEG) containing flavonoids on the behavioral status and learning of intact and ovariectomized adult female rats has been
studied. The DCEG preparation was administered in low (0.5 mg/kg, i.p.) and high (5.0 mg/kg, i.p.) daily doses over a period
of 14 days and the results were evaluated on the passive avoidance situation model and in the open field test. It was established
that the chronic administration of DCEG in both low and high doses produced correction of the passive avoidance performance
in ovariectomized female rats. The administration of DCEG in a low dose also positively influenced the structure of purposeful
behavior of females with deficiency of estrogens.
__________
Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 39, No. 8, pp. 27 – 29, August, 2005. 相似文献
43.
44.
Lidong Zhang James E Littlejohn Yu Cui Xiaobo Cao Chander Peddaboina W Roy Smythe 《Molecular cancer》2010,9(1):110
Background
Bortezomib, a proteasome-specific inhibitor, has emerged as a promising cancer therapeutic agent. However, development of resistance to bortezomib may pose a challenge to effective anticancer therapy. Therefore, characterization of cellular mechanisms involved in bortezomib resistance and development of effective strategies to overcome this resistance represent important steps in the advancement of bortezomib-mediated cancer therapy. 相似文献45.
卫生保健课程是以贯彻"预防为主"的方针、实现"健康为人人,人人为健康"的一门重要学科。笔者根据数年的教学实践,结合学生的课堂调查结果,总结卫生保健课程教学中常见的误区,以期同行在教学中避免走进误区,更好地为教学服务。 相似文献
46.
47.
48.
Murat Hamit Aytar Fikret Doğulu Berker Cemil Ertan Ergün Gökhan Kurt Kemali Baykaner 《Child's nervous system》2007,23(6):719-721
Introduction Iniencephaly, a neural tube defect involving occiput and inion and combined with rachischisis of the cervical, thoracic spine,
and retroflexion position of the head is a very rare congenital abnormality of the fetus–newborn with a 0.1–10 of 10,000 prevalence.
This abnormality’s prognosis is thought to be dismal. This abnormality can be associated with other abnormalities such as
anencephaly, encephalocele, hydrocephalus, cyclopia, absence of the mandible, cleft lip and palate, cardiovascular disorders,
diaphragmatic hernia, renal abnormalities, overgrowth of the arms compared to the legs, and club food and gastrointestinal
atresia.
Discussion Most of the patients are dead born, and the others die in a few hours. There are only six previously documented long-term
survivors. In our case, our patient with iniencephalic signs and findings is still living. She is 2 years old now. We think
that this patient presents a mild form of iniencephaly. 相似文献
49.
M. Yu. Stepanichev M. L. Libe I. A. Chernyshevskaya A. G. Moiseenok N. V. Gulyaeva 《Neurochemical Journal》2007,1(3):244-248
Administration of cholinotoxin etylcholine aziridinium (AF64A) into the brain selectively induces nonrever-sible cholinergic deficit. Wistar rats were injected intracerebroventricularly bilaterally with AF64A at doses of 1–3 nmol/ventricle. 28 days later the number of neurons survived was counted in dorsolateral, intermediate and medial groups of cells of the medial septum. AF64A induced a decrease in neuronal density and expression of cholineacetyl transferase at all doses used as well as in all regions studied. Brain sections were also stained for NADPH-diaphorase representing neuronal NO-synthase. Effects of AF64A on NADPH-diaphorase expression depended on the region studied. The number of NADPH-diaphorase-positive cells increased in the medial cellular group where more cholineacetly transferase-positive cells survived. In contrast, decrease in NADPH-diaphorase expression in the dorsolateral group of cells coincided with low level of cholineacetyltransferase-po-sitive neurons. The data presented suggest that in the AF64A-dependent model of neurodegeneration NO may play a neuroprotective function. 相似文献
50.
在管理期刊工作的实践中,探讨如何提高期刊利用率的策略,根据馆情,利用现代科技手段为读者提供高质量的信息服务。 相似文献