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41.
The authors report 3 unrelated Turkish cases of disorganizationlike syndrome. All of these patients have accessory limbs, and 2 of them have accessory genitourinary structures. Interestingly, one of these patients has extrophia vesicalis of accessory bladder. None of them have chromosomal abnormality. Here the authors present distribution of findings of these cases. 相似文献
42.
Abstract.
Introduction:
Few studies have tested the hypothesis of whether the
beneficial effect of Stroke Units (SUs) can be reproduced in
routine clinical practice and whether SU are also superior to
neurological wards [NWs]. We aimed to compare the outcomes of
patients of a newly implemented SU to the outcomes of patients
hospitalized in a NW.
Methods:
We made a before-after comparison of 352 SUs and 352 NWs
patients after adjusting for case-mixes by the multivariate
method. Subgroup analyses were also performed to evaluate which
patient groups benefit the most. In-hospital case-fatality,
proportion of independent patients at discharge, length of
hospital stay (LOHS), medical complication rate were the main
outcome measures.
Results:
Adjusted in-hospital case fatality was significantly
reduced in the SUs (OR: 0.44, 95 % CI: 0.26–0.76; p = 0.003).
The proportion of independent patients at discharge and patients
having medical complications was not different. Length of
hospital stay was shorter in SU patients (13.76 days vs. 16.72
days, p = 0.003). Treatment in the SUs decreased case fatality
in many subgroups [men, elderly, early admitted, severe stroke,
co-morbidity present and ischemic stroke groups].
Discussion:
The results of randomized trials in favor of SUs can be
reproduced in routine clinical practice. The benefit of SU care
seems to be more apparent with advancing age and increasing
stroke severity. Stroke Unit seems to be a better alternative to
an experienced NW. 相似文献
43.
1 临床资料 1996~1998发病后12h就诊的住院AMI患者130(男76,女54)例,年龄(54.2±15)岁.室性心律失常统计以AMI后96h内为限.前壁心肌梗塞28例,下壁心肌梗塞28例,前间壁心肌梗塞19例,高侧壁心肌梗塞17例,后壁心肌梗塞20例,广泛性心肌梗塞18例.入院时首先描记第1份12导联心电图,入院后依病情随时描记心电图变化情况,并持续心电监护96h,室性心律失常以出现频发室性早搏(3次/min),室性早搏在Ⅱ级以上(LDWNWV)级,成对室速,室性心动过速为观察对象.1… 相似文献
44.
Angus YK Lam Anthony F Jorm Daniel FK Wong 《International journal of mental health systems》2010,4(1):18
Background
The aim of this study was to investigate in members of the Chinese community in Melbourne the impact of Mental Health First Aid (MHFA) training on knowledge about mental disorders and on attitudes to people with mental illness. The hypotheses were that at the end of the training participants would have increased knowledge of mental disorders and related treatments, and decreased negative attitudes towards people with mental disorders. 相似文献45.
46.
47.
REM sleep behaviour disorder (RSBD) is a recently described parasomnia characterised by a history of excessive nocturnal motor activity and absence of muscle atonia during REM sleep. Only limited literature is available on this condition. The exact prevalence is unclear, but recent studies suggest it might not be an uncommon condition. The elderly are more often affected and there is a male preponderance. While transient RSBD can be seen after taking certain drugs or during drug withdrawal, the chronic type is usually idiopathic or associated with an underlying degenerative neurological condition. It can result in considerable distress and/or serious injury to the patients or their bed partners. Differential diagnoses include sleep-walking, night terrors, nightmares, nocturnal seizures, obstructive sleep apnoea, post-traumatic stress disorder, dissociative states and nocturnal confusional states. The dramatic response to clonazepam highlights the importance of recognition and appropriate treatment of this sleep disorder. 相似文献
48.
The mean platelet volume in patients with obesity 总被引:3,自引:0,他引:3
Coban E Ozdogan M Yazicioglu G Akcit F 《International journal of clinical practice》2005,59(8):981-982
Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [body mass index (BMI) > or =30 kg/m(2)] matched for age and gender. The MPV was significantly higher in obese group than in non-obese control group (10.3 +/- 1.2 vs. 9.0 +/- 0.8 fl, p < 0.01). MPV was positively correlated with BMI in obese group (p < 0.05). Increased MPV may be a possible cause for increased cardiovascular risk in patients with obesity. 相似文献
49.
In general, resistance to fluoroquinolones (FQs) in gram-negative bacteria is acquired either by mutations in DNA gyrase and topoisomerase IV or by active export of the agents via antibiotic efflux pumps. Reduced porin expression is also proposed to be another mechanism leading to resistance. In this study, interaction between levofloxacin, ofloxacin, and ciprofloxacin with MC-207,110 (multidrug efflux pump inhibitor) was investigated by a checkerboard assay using Pseudomonas aeruginosa. Levofloxacin, ofloxacin, and ciprofloxacin were tested at different concentrations (0.06-64 microg/ml) and MC-207,110 was tested at a concentration range of 4-128 microg/ml. In the presence of MC-207,110 (at 128, 64, 32, 16 microg/ml) resistance to FQs was inhibited significantly and MIC values were decreased, except at 8 and 4 microg/ml of MC-207,110. When MC-207,110 was used, resistance of P. aeruginosa to FQs in vitro was inhibited significantly, suggesting that MC-207,110 may be useful for use in clinical treatment protocols to overcome FQs resistance. 相似文献
50.
目的:蒿甲醚除了具有良好的临床治疗作用外,对正常组织有极大的副作用。实验拟观察蒿甲醚对大鼠肺泡Ⅱ型上皮细胞的影响。方法:实验于2005-09-20/2007-03-10在山东省泰山医学院生命科学研究所、中心实验室和机能实验室完成。①实验材料:蒿甲醚购自昆明制药厂,分析纯,使用前先进行预处理,处理方法:研磨后用溶液配成1g/L的母液,超声助溶解后供实验用。Wistar大鼠70只,体质量(70±15)g,雌雄不拘,由山东大学医学院实验动物中心提供。实验过程中对动物处置符合动物伦理学标准。②实验方法:将大鼠随机分为普通饲料对照组(n=10)和实验组(n=60),实验组分6个亚组,分别在饲料中加入0.1,0.2,0.4,0.8,1.6,3.2mg/kg的蒿甲醚。采用单细胞凝胶电泳技术观察大鼠肺泡Ⅱ型上皮细胞DNA的改变。结果:70只大鼠,饲养过程中实验组死亡6只,死亡原因为饲料添加蒿甲醚造成。当饲料中的蒿甲醚浓度为0.1mg/kg时,大鼠肺泡Ⅱ型上皮细胞DNA损伤率与对照组相比,差异无统计学意义;饲料中的蒿甲醚浓度超过0.2mg/kg时,大鼠肺泡Ⅱ型上皮细胞DNA损伤率明显增加,与对照组相比,差异有统计学意义。且损伤程度与饲料中蒿甲醚含量呈正相关。结论:当饲料中的蒿甲醚浓度超过0.2mg/kg时,蒿甲醚可在一定程度上改变肺泡Ⅱ型上皮细胞的DNA生物学特性。且随着蒿甲醚浓度的升高,这种损害更为明显。 相似文献