Transplant-associated and blood transfusion-associated tropical and parasitic infections

Blood transfusion and transplantation may represent efficient mechanisms of spreading infectious agents to naive populations. In the developed countries, as a consequence of globalization, several factors such as international commerce, tourism, and immigration have acted as important features for the emergence or reemergence of infectious diseases previously referred to as tropical. This article reviews the relevant bacterial, protozoan and viral infections that are more frequently associated with blood transfusion and/or solid organ or marrow transplantation and may affect susceptible populations worldwide.     

High-velocity low-amplitude thrust manipulation of the lumbar spine immediately modifies soleus T reflex in asymptomatic adults

BackgroundHigh-velocity low-amplitude thrust manipulations (HVLAM) are routinely used in osteopathic treatment. Despite the large number of studies that have been realized till now, the effects of spinal HVLAM on the physiological properties of muscles and nerves are not fully characterized.ObjectiveThe present study was designed to investigate the effects of a spinal lumbar L4/L5 HVLAM on the functional properties of the soleus T reflex in asymptomatic young adults.DesignControlled pre/post measures experimental design.MethodsRight and left soleus T reflexes were elicited by striking right and left Achilles tendons with an instrumented reflex hammer and the electromyographic (EMG) signals were monitored in right and left soleus muscles. The amplitude and latency of EMG responses were measured before and after the delivery of a HVLAM targeting the L4/L5 segment. The conduction velocity was calculated from the latency value.Subjects50 asymptomatic adults met all inclusion criteria. They were randomly allocated to either group a) receiving a sham manipulation (SM), or b) a HVLAM. Because of subject loss, the final size of SM and HVLAM groups was 24 and 18, respectively.ResultsOur data show that the conduction velocity, but not the amplitude of the T reflex, is significantly increased by HVLAM in both soleus muscles with small to medium effect size. SM neither changes the amplitude nor modifies the conduction velocity.ConclusionOur data show that a lumbar L4/L5 HVLAM modifies the electrophysiological properties of the soleus T reflex.     

Cross-sectional multicentre study on the cohort of all the French junior lecturers in general practice

Background: General practice became an academic discipline quite recently in many western countries. In France, junior lecturer work is specified in a three-part mandate: medical work in general practice, teaching in the university, and research. Since 2007, 130 junior lecturers have been appointed in general practice. The aim of the creation of junior lecturer status was to align general practice with other specialties and to develop research and education in primary care.

Objectives: To describe the healthcare, teaching and research undertaken by junior lecturers in general practice, practising in October 2014.

Methods: A cross-sectional multicentre study using an online self-administered questionnaire on the cohort composed of all the junior lecturers in general practice with open questions and the qualitative analysis of written verbatim accounts.

Results: Of the 95 junior lecturers practising at the date of the study, 75 (79%) responded; average age 32 years; gender ratio (F/M) 2.4:1. They spent five, two and three half-days per week respectively in healthcare, teaching and research. The healthcare activity was predominantly carried out in the community (73%). Thirty-nine per cent worked as part of a multi-professional team taking on 50 consultations per week. Most of the educational work involved lecturing and mentoring students specializing in general practice (median 86?hours per year). Research output increased during the fellowship. Research topics were varied and relevant to the disciplinary field.

Conclusion: During the fellowship, the balancing, and even the reinforcement, of healthcare and research contributions were accompanied by a significant investment in educational provision.