全文获取类型
收费全文 | 11139篇 |
免费 | 754篇 |
国内免费 | 39篇 |
专业分类
耳鼻咽喉 | 171篇 |
儿科学 | 287篇 |
妇产科学 | 247篇 |
基础医学 | 1521篇 |
口腔科学 | 471篇 |
临床医学 | 885篇 |
内科学 | 2518篇 |
皮肤病学 | 239篇 |
神经病学 | 911篇 |
特种医学 | 212篇 |
外科学 | 1660篇 |
综合类 | 82篇 |
现状与发展 | 1篇 |
一般理论 | 8篇 |
预防医学 | 1109篇 |
眼科学 | 187篇 |
药学 | 754篇 |
中国医学 | 39篇 |
肿瘤学 | 630篇 |
出版年
2023年 | 74篇 |
2022年 | 167篇 |
2021年 | 392篇 |
2020年 | 241篇 |
2019年 | 426篇 |
2018年 | 435篇 |
2017年 | 287篇 |
2016年 | 301篇 |
2015年 | 340篇 |
2014年 | 407篇 |
2013年 | 481篇 |
2012年 | 694篇 |
2011年 | 727篇 |
2010年 | 405篇 |
2009年 | 344篇 |
2008年 | 562篇 |
2007年 | 614篇 |
2006年 | 592篇 |
2005年 | 497篇 |
2004年 | 475篇 |
2003年 | 390篇 |
2002年 | 379篇 |
2001年 | 259篇 |
2000年 | 330篇 |
1999年 | 248篇 |
1998年 | 79篇 |
1997年 | 52篇 |
1996年 | 40篇 |
1995年 | 51篇 |
1994年 | 60篇 |
1993年 | 44篇 |
1992年 | 121篇 |
1991年 | 133篇 |
1990年 | 116篇 |
1989年 | 113篇 |
1988年 | 89篇 |
1987年 | 83篇 |
1986年 | 81篇 |
1985年 | 92篇 |
1984年 | 54篇 |
1983年 | 41篇 |
1980年 | 32篇 |
1979年 | 56篇 |
1978年 | 60篇 |
1977年 | 33篇 |
1975年 | 50篇 |
1974年 | 57篇 |
1973年 | 43篇 |
1972年 | 35篇 |
1970年 | 32篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
171.
172.
Characterization of four Latin American families confirms previous findings and reveals novel features of acid‐labile subunit deficiency
下载免费PDF全文
![点击此处可从《Clinical endocrinology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Paula A. Scaglia Ana C. Keselman Débora Braslavsky Lucía C. Martucci Liliana M. Karabatas Sabina Domené Mariana L. Gutiérrez María G. Ballerini María G. Ropelato Angela Spinola‐Castro Adriana A. Siviero‐Miachon Juliana Saito Tartuci María Sol Rodríguez Azrak Rodolfo A. Rey Héctor G. Jasper Ignacio Bergadá Horacio M. Domené 《Clinical endocrinology》2017,87(3):300-311
173.
Substitutions in position 222 of haemagglutinin of pandemic influenza A (H1N1) 2009 viruses in Spain
Juan Ledesma Francisco Pozo Mercedes Prez Ruiz Jose María Navarro Luis Pieiro Milagros Montes Sonia Prez Castro Jonathan Surez Fernndez Juan García Costa Mirian Fernndez Juan Carlos Galn María Teresa Cuevas Inmaculada Casas Pilar Prez Brea Spanish Influenza Surveillance System 《Journal of clinical virology》2011,51(1):75-78
174.
175.
176.
Luis Felipe Casado José Ángel Hernández Isidro Jarque María Echave Miguel Angel Casado Antonio Castro 《European journal of haematology》2018,100(3):264-272
Objective
To evaluate the incremental cost‐utility ratio (ICUR) of idelalisib in combination with rituximab (IR) versus rituximab monotherapy (R) in the treatment of patients with relapsed or refractory (R/R) chronic lymphocytic leukaemia (CLL), from the Spanish National Health System (NHS) perspective.Methods
A partitioned survival Markov model for a lifetime horizon (30 years) was developed to estimate costs (€, 2016) and quality‐adjusted life years (QALY) with IR and R. Initial cohort included patients with CLL receiving a second or subsequent line (2L) of treatment with IR or R. Survival data were based on CLL clinical trial. Drug, administration, monitoring, adverse events and clinical management of CLL costs were included in the model. Costs and outcomes were discounted using a 3% annually. Deterministic and probabilistic sensitivity analyses (PSA) were performed.Results
Compared to R, 2L IR treatment resulted in QALY gain of 3.147 (4.965 versus 1.818). Total costs were €118 254 for IR versus €23 874 for R. ICUR was €29 990/QALY gained with IR versus R. In the PSA, IR was cost‐effective in 78% of iterations using a threshold of €45 000/QALY.Conclusion
IR can be considered a cost‐effective treatment compared to R, in the treatment of R/R CLL patients for the Spanish NHS. 相似文献177.
Accumulation of advanced glycation end products is associated with macrovascular events and glycaemic control with microvascular complications in Type 2 diabetes mellitus
下载免费PDF全文
![点击此处可从《Diabetic medicine》网站下载免费的PDF全文](/ch/ext_images/free.gif)
178.
179.
Is parental oral health literacy a predictor of children's oral health outcomes? Systematic review of the literature
下载免费PDF全文
![点击此处可从《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Ramon Targino Firmino Fernanda Morais Ferreira Carolina Castro Martins Ana Flávia Granville‐Garcia Fabian Calixto Fraiz Saul Martins Paiva 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2018,28(5):459-471
180.
Vivian Siqueira Santos Gonçalves Eliane Rodrigues de Faria Sylvia do Carmo Castro Franceschini Silvia Eloiza Priore 《Jornal de pediatria》2013,89(6):567-574
Objectivethis study was performed to determine the predictive capacity of four different bioelectrical impedance analysis (BIA) devices in the assessment of adolescents, with and without a protocol.Methodsa cross-sectional study was performed with 215 adolescents aged 10 to 14 years, of both genders, evaluated through anthropometry and body composition by dual energy X-ray absorptiometry (DXA) and by four different BIA devices, with and without a protocol. The following tests were used: Kolmogorov-Smirnov's, chi-squared, Student's t or Mann-Whitney's, Kruskal-Wallis's, Wilcoxon's, and kappa index. The ROC curves were constructed and the sensitivity, specificity, and positive and negative predictive values were calculated.Resultsof the 215 adolescents, 44.2% had excessive body fat. The tetrapolar BIA device equipped with eight tactile electrodes showed more sensitivity and results that were closer to those obtained by DXA (area under the ROC curve [AUC] = 0.964 with protocol and AUC = 0.973 without protocol, p < 0.001), as well as greater agreement (k = 0.67 with protocol and k = 0.63 without protocol, p < 0.001). The evaluation without protocol was similar to that by DXA in most investigated situations (p > 0.05).ConclusionBIA is capable of predicting alterations in adolescents’ body composition. When it is impossible to perform the assessment with a protocol, its results may be useful in population studies. 相似文献