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51.
Donatella Peca Renata Boldrini Jan Johannson Joseph T Shieh Arianna Citti Stefania Petrini Teresa Salerno Salvatore Cazzato Raffaele Testa Francesco Messina Alfredo Onofri Giovanna Cenacchi Per Westermark Nicola Ullmann Paola Cogo Renato Cutrera Olivier Danhaive 《European journal of human genetics : EJHG》2016,24(5):780
52.
Rauch Aymeric Cazzato Roberto Luigi Garnon Julien Shaygi Behnam Tsoumakidou Georgia Caudrelier Jean Bauones Salem Koch Guillaume Lipsker Dan Gangi Afshin 《Cardiovascular and interventional radiology》2017,40(8):1285-1289
CardioVascular and Interventional Radiology - This study aims to discuss MRI-guided cryoablation (CA) of in-transit (IT) metastases from melanoma and to retrospectively present our preliminary... 相似文献
53.
Tsoumakidou Georgia Too Chow Wei Koch Guillaume Caudrelier Jean Cazzato Roberto Luigi Garnon Julien Gangi Afshin 《Cardiovascular and interventional radiology》2017,40(3):331-342
CardioVascular and Interventional Radiology - Vertebral compression fracture (VCF) is an important cause of severe debilitating back pain, adversely affecting quality of life, physical function,... 相似文献
54.
R. Del Vescovo F. Pisanti V. Russo S. Battisti R. L. Cazzato F. D’ Agostino F. Giurazza C. C. Quattrocchi E. Faiella R. Setola R. Giulianelli R. F. Grasso B. Beomonte Zobel 《La Radiologia medica》2013,118(5):851-862
Purpose
The authors sought to determine the diagnostic performance of dynamic contrast-enhanced magnetic resonance (DCE-MR) imaging in the evaluation of prostate cancer before and after transrectal high-intensity focused ultrasound (HIFU) treatment.Materials and methods
We analysed 25 patients with prostate cancer. The prostate-specific antigen (PSA) value was evaluated 1, 4 and 6 months after treatment. DCE-MR imaging was performed the day prior to and 1, 4 and 6 months after HIFU treatment. Transrectal prostate biopsies were obtained at the time of diagnosis and 6 months after treatment.Results
Before treatment, intraglandular lesions were considered to be potential sites of neoplasm and subsequently confirmed as sites of prostate adenocarcinoma in all 25 patients based on prostatespecific antigen (PSA) values and histological examinations (rho=1; p<0.001). Using histology as the gold standard, DCE-MR imaging displayed 100% sensitivity, 100% specificity, 100% positive predictive value and 100% negative predictive value before treatment. After HIFU treatment, DCE-MR imaging showed 100% sensitivity and 96% specificity.Conclusions
DCE-MR imaging can be used to visualise prostate adenocarcinoma. Several morphological and postgadolinium modifications in the follow-up DCE-MR images after HIFU treatment were also observed. 相似文献55.
Riccardo Del Vescovo Claudia Lucia Piccolo Nicoletta Della Vecchia Francesco Giurazza Roberto Luigi Cazzato Rosario Francesco Grasso Bruno Beomonte Zobel 《European journal of radiology》2014
Objective
Pelvic floor dysfunctions affect a very high proportion of female population. Magnetic resonance imaging is the only technique able to provide a multiplanar overview of pelvic organs and muscles without the use of ionizing radiation. The aim of our prospective study is to objectively evaluate the effectiveness of perineal re-education applying MR technique.Materials and methods
22 patients affected by stress urinary incontinence were enrolled in our prospective study. They underwent urogynaecological, urodynamic examinations, and a questionnaire about symptoms (ICIQ-UI) to investigate the degree of their interference with daily activities. Then they underwent a morphological and dynamic MR exam.Results
The pre-perineal rehabilitation MR examinations showed an asymmetry of the levator ani muscle in 87% of patients; the remaining 13% showed a muscular bilateral volume reduction. In the group with unilateral defect, the muscle total volume had values between 15 and 21 cm3. Its overall volume was 34.2% smaller on the defective side (9.28 ± 0.26 cm3) compared to the normal side (12.64 ± 12.31 cm3, P < 0.001).In patients with a bilateral impairment, the muscle was replaced by fibro-fatty tissue, without a significant asymmetry between the two sides. The post-perineal rehabilitation MR tests showed three different degrees of response to therapy, with a “complete response” found in 67% of patients and no response in 13%.Conclusions
MR is an useful tool in the management of patients affected by stress urinary incontinence with indication for perineal rehabilitation. Its objective data allow to distinguish different types of response to therapy and, consequently, different outcomes in terms of additional treatments. 相似文献56.
Depression and anxiety in multiple sclerosis. A clinical and MRI study in 95 subjects 总被引:2,自引:0,他引:2
Marino Zorzon Roberto de Masi Davide Nasuelli Maja Ukmar Roberto Pozzi Mucelli Giuseppe Cazzato Alessio Bratina Robert Zivadinov 《Journal of neurology》2001,248(5):416-421
The aim of the present study was to investigate the relationship between involvement of specific areas of the brain and the
occurrence of depression and anxiety in patients with multiple sclerosis. We studied 95 patients (62 women and 33 men, mean
age 39.5 years, SD 11.2) with definite MS, 97 patients (65 women and 32 men, mean age 40.7, SD 11.9) suffering from chronic
rheumatoid diseases and 110 healthy subjects (71 women and 39 men, mean age 40.1, SD 12.7). The disability, the independence,
the cognitive performances, the depressive and anxiety symptoms were assessed. The diagnosis of major depression was made
according to the DSM-IV. The patients with multiple sclerosis underwent a 1.5 Tesla magnetic resonance examination including
T1 and T2 weighted images. Calculation of regional and total lesion loads and brain volumes were performed. The number (%)
of subjects with a diagnosis of major depression was 18 (18.9) among MS cases, 16 (16.5) among controls with chronic disease
(p=NS), and 4 (3.6) among healthy volunteers (p < 0.0001). The Hamilton Depression and Anxiety rating scales median scores
were 5 and 18, respectively in the MS patients, 5 (p= NS) and 14 (p= NS) in the chronic rheumatoid diseases controls, and
3 (p= < 0.0001) and 6 (p= < 0.0001) in the healthy controls. Both severity of depressive symptoms and diagnosis of major depression
correlated, albeit weakly, with right frontal lesion load (r=0.22, p=0.035, and r=0.23, p=0.026, respectively) and right temporal
brain volume (r=0.22, p=0.005 and r=0.22, p=0.036, respectively). The severity of depression was related significantly also
with total temporal brain volume (r=0.26, p=0.012), right hemisphere brain volume (r=0.25, p=0.015), disability (r=0.30, p=0.003)
and independence of MS cases (r=−0.26, p=0.01). The anxiety did not correlate significantly with any of the measures of regional
and total lesion loads and brain volume or with any of the considered clinical variables. The similar frequency of depression
and severity of depressive symptoms in MS patients and in chronic disease patients, the significant difference in this respect
with the normal controls, and the significant correlation between depression and the disability measures would suggest a psychological
reaction to the impact of the disease but the relationship between depression and the alterations in the frontal and temporal
lobes of the right hemisphere supports, on the contrary, the causative role of organic brain damage. The lack of any significant
association between symptoms of anxiety and either MRI abnormalities or clinical variables led us to the opinion that anxiety
is a reactive response to the psychosocial pressure put on the patients.
Received: 9 September 2000 / Received in revised form: 30 November 2000 / Accepted: 20 December 2000 相似文献
57.
58.
G. Neri M. Pugliese A. Castriotta V. Mastronardi P. Pasqualini A. Colasante F. Cazzato R. Talamonti G. Del Boccio 《Medical hypotheses》2013
Laryngopharyngeal reflux (LPR) indicates the reflux-induced extra-esophageal disorders. LPR and gastroesophageal reflux disease (GERD) occur by the same mechanism: the escape of gastric contents into the esophagus and beyond. However, the classic GERD symptoms are not typical in LPR disease, which can cause a lot of symptoms none of which is specific, making the diagnosis often elusive. The protective mechanisms present in the esophagus are entirely lacking in the larynx, and more generally in upper aerodigestive tract, making them particularly vulnerable to injury from acidic gastric contents. Since gastric acid backflow can affect supraesophageal structures, even in the absence of heartburn or regurgitation symptoms, an early diagnosis is important to prevent the onset of histological modifications in the supraesophageal mucosa. 相似文献
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