全文获取类型
收费全文 | 3399篇 |
免费 | 181篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 146篇 |
妇产科学 | 151篇 |
基础医学 | 239篇 |
口腔科学 | 126篇 |
临床医学 | 319篇 |
内科学 | 802篇 |
皮肤病学 | 153篇 |
神经病学 | 198篇 |
特种医学 | 133篇 |
外科学 | 786篇 |
综合类 | 44篇 |
预防医学 | 66篇 |
眼科学 | 98篇 |
药学 | 131篇 |
中国医学 | 7篇 |
肿瘤学 | 116篇 |
出版年
2023年 | 29篇 |
2022年 | 59篇 |
2021年 | 84篇 |
2020年 | 66篇 |
2019年 | 69篇 |
2018年 | 110篇 |
2017年 | 80篇 |
2016年 | 130篇 |
2015年 | 122篇 |
2014年 | 129篇 |
2013年 | 211篇 |
2012年 | 255篇 |
2011年 | 259篇 |
2010年 | 144篇 |
2009年 | 103篇 |
2008年 | 234篇 |
2007年 | 246篇 |
2006年 | 209篇 |
2005年 | 202篇 |
2004年 | 177篇 |
2003年 | 158篇 |
2002年 | 140篇 |
2001年 | 84篇 |
2000年 | 53篇 |
1999年 | 50篇 |
1998年 | 18篇 |
1997年 | 8篇 |
1996年 | 8篇 |
1995年 | 5篇 |
1994年 | 9篇 |
1993年 | 6篇 |
1992年 | 17篇 |
1991年 | 9篇 |
1990年 | 9篇 |
1989年 | 8篇 |
1988年 | 9篇 |
1987年 | 10篇 |
1986年 | 6篇 |
1985年 | 8篇 |
1984年 | 6篇 |
1983年 | 3篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 4篇 |
1979年 | 6篇 |
1975年 | 3篇 |
1974年 | 5篇 |
1970年 | 4篇 |
1967年 | 6篇 |
1966年 | 3篇 |
排序方式: 共有3599条查询结果,搜索用时 0 毫秒
61.
Emre Tekgündüz Mehmet Yılmaz Mehmet Ali Erkurt Ilhami Kiki Ali Hakan Kaya Leylagul Kaynar Inci Alacacioglu Guven Cetin Ibrahim Ozarslan Irfan Kuku Gulden Sincan Ozan Salim Sinem Namdaroglu Abdullah Karakus Volkan Karakus Fevzi Altuntas Ismail Sari Gulsum Ozet Fatih Demirkan 《Transfusion and apheresis science》2018,57(1):27-30
Thrombotic microangiopathies (TMAs) are rare, but life-threatening disorders characterized by microangiopathic hemolytic anemia and thrombocytopenia (MAHAT) associated with multiorgan dysfunction as a result of microvascular thrombosis and tissue ischemia. The differentiation of the etiology is of utmost importance as the pathophysiological basis will dictate the choice of appropriate treatment.We retrospectively evaluated 154 (99 females and 55 males) patients who received therapeutic plasma exchange (TPE) due to a presumptive diagnosis of TMA, who had serum ADAMTS13 activity/anti-ADAMTS13 antibody analysis at the time of hospital admission. The median age of the study cohort was 36 (14-84). 67 (43.5%), 32 (20.8%), 27 (17.5%) and 28 (18.2%) patients were diagnosed as thrombotic thrombocytopenic purpura (TTP), infection/complement-associated hemolytic uremic syndrome (IA/CA-HUS), secondary TMA and TMA-not otherwise specified (TMA-NOS), respectively. Patients received a median of 18 (175) plasma volume exchanges for 14 (153) days. 81 (52.6%) patients received concomitant steroid therapy with TPE. Treatment responses could be evaluated in 137 patients. 90 patients (65.7%) achieved clinical remission following TPE, while 47 (34.3%) patients had non-responsive disease. 25 (18.2%) non-responsive patients died during follow-up. Our study present real-life data on the distribution and follow-up of patients with TMAs who were referred to therapeutic apheresis centers for the application of TPE. 相似文献
62.
63.
Ceren Orhan Ozgun Kaya Kara Serap Kaya Turkan Akbayrak Mintaze Kerem Gunel Gül Baltaci 《Disability and rehabilitation》2018,40(1):10-20
Purpose: The aim of this study was to investigate the effects of connective tissue manipulation (CTM) and Kinesio Taping® (KT) on constipation and quality of life in children with cerebral palsy (CP).Method: This study was designed as a randomized controlled trial. Forty children diagnosed with chronic constipation based on Rome III criteria were randomly assigned to CTM group [6 females, 7 males; 8 y 6?mo (SD = 3y 4?mo)], KT group [7 female, 7 male; 8y 7?mo (SD =3y 5?mo)] or control group [6 female, 7 male; 8y 3?mo (SD = 3y 6?mo)]. All patients were assessed with 7-day bowel diaries, Bristol Stool Form Scale (BSFS), Visual Analog Scale (VAS), and Pediatric Quality of Life Inventory (PEDsQL). Kruskal-Wallis, Wilcoxon’s signed-rank, and Mann–Whitney U tests were used to determine intra-group and inter-group differences. The level of significance was p?0.05.Results: Among the CTM, KT, and control groups, there were statistically significant differences regarding the changes in defecation frequency (2.46, 3.00, 0.30, ES 1.16, p?0.001), duration of defecation (5.07, 5.35, 0.15, ES 2.37, p?=?0.003), BSFS (1.84, 2.14, 0.07, ES 0.91, p?0.001), VAS (4.83, 3.87, 0.23, ES 1.98, p?0.001), and PEDsQL total scores (7, 14, 8.36, ?0.85, ES 4.08, p?0.001).Conclusions: This study revealed that CTM and KT seem equally effective physiotherapy approaches for the treatment of pediatric constipation and these approaches may be added to bowel rehabilitation program.
- Implications for rehabilitation
CTM and KT have similar effectiveness in alleviating the constipation-related symptoms and improving quality of life in children with CP.
CTM and KT can be integrated into bowel rehabilitation programs.
Considering the characteristics of patients, these treatment options can be used as an alternative of each other by physiotherapists.
64.
65.
Nedim Durmus Sefa Gültürk Tijen Kaya Tuncer Demir Mesut Parlak Ahmet Altun 《Indian journal of pharmacology》2015,47(1):34-38
Objectives:It is suggested that excessive calcium entry into neurons is the main triggering event in the initiation of epileptic discharges. We aimed to investigate the role of T and N type calcium channels in absence epilepsy experimental model.Results:Beta and delta recording ratios in 1 μM/5 μl mibefradil group was significantly different from basal and other dose-injected groups. Beta, alpha, and theta recordings in 0.2 μM/5 μl w-Conotoxin MVIIA group was significantly different from basal and other dose-injected groups. In w-Conotoxin MVIIA after mibefradil group, beta, alpha, and theta recording ratios were significantly different from basal and mibefradil group. Mibefradil and w-Conotoxin MVIIA significantly decreased the frequency and duration of SWDs. The decrease of frequency and duration of SWDs in mibefradil group was significantly different from w-Conotoxin MVIIA group. The frequency and duration of SWDs significantly decreased in w-Conotoxin MVIIA after mibefradil group compared with basal, mibefradil, and w-Conotoxin MVIIA groups.Conclusions:We concluded that both T and L type calcium channels play activator roles in SWDs and have positive effects on frequency and duration of these discharges. These results are related with their central effects more than peripheral effects.KEY WORDS: Epilepsy, mibefradil, T and N type calcium channels, Wistar Albino Glaxo/Rij rats, w-Conotoxin MVIIA 相似文献
66.
Rohde Sofie Muslem Rahatullah Kaya Emrah Dalinghaus Michel van Waning Jaap I. Majoor-Krakauer Danielle Towbin Jeffery Caliskan Kadir 《Heart failure reviews》2022,27(1):15-28
Heart Failure Reviews - Noncompaction cardiomyopathy (NCCM) is a disease characterized by hypertrabeculation, commonly hypothesized due to an arrest in compaction during fetal development. In 2006,... 相似文献
67.
68.
69.
Yesim Salik Sengul Nergis Kaya Gamze Yalcinkaya Muge Kirmizi Orhan Kalemci 《Explore (New York, N.Y.)》2021,17(4):334-339
ContextPatients who have suffered from persistent symptoms often undergo lumbar spinal surgery (LSS). Motor imagery should be added to postoperative home exercises to reduce patient complaints.ObjectiveThe aim of this study was to compare the effects of home exercise plus motor imagery and only home exercise in patients undergoing LSS.DesignA randomized controlled study.SettingsThis study was designed by researchers at Dokuz Eylul University.ParticipantsThirty-seven patients undergoing LSS were randomized to motor imagery group (n = 19) and control group (n = 18).Main outcome measuresPain was measured by Visual Analogue Scale, disability related to low back pain by Oswestry Disability Index, pain-related fear by Tampa Scale of Kinesiophobia, depression by Beck Depression Inventory, quality of life by World Health Organization Quality of Life Scale-Short Form (WHOQOL-BREF). All assessments were repeated in the preoperative period, three weeks after and six weeks after the surgery.InterventionsMotor imagery group underwent home exercise plus motor imagery program applied by voice recording. Control group underwent only home exercise program. Exercise program compliance was monitored by exercise diary and telephone calls once every week.ResultsThere was a significant improvement in pain at rest and during activity, disability, kinesiophobia, depression, physical health and psychological sub-parameters of WHOQOL-BREF between preoperative period, and the third week and sixth week in both groups (p < 0.05). When comparing groups for gain scores, there was a more significant improvement in pain during activity in motor imagery group (p < 0.05). Motor imagery should be addressed as an effective treatment after LSS. 相似文献
70.