Über die Kultur des Leprabacillus und die Übertragung der Lepra auf Tiere

Ohne ZusammenfassungHierzu Taf. VI.     

Cross-cultural validity of four quality of life scales in persons with spinal cord injury

Background  

Quality of life (QoL) in persons with spinal cord injury (SCI) has been found to differ across countries. However, comparability of measurement results between countries depends on the cross-cultural validity of the applied instruments. The study examined the metric quality and cross-cultural validity of the Satisfaction with Life Scale (SWLS), the Life Satisfaction Questionnaire (LISAT-9), the Personal Well-Being Index (PWI) and the 5-item World Health Organization Quality of Life Assessment (WHOQoL-5) across six countries in a sample of persons with spinal cord injury (SCI).     

Evaluation of Brazilian plants on cancer chemoprevention targets in vitro

Cancer is a leading cause of death worldwide. Cancer chemoprevention is one of the promising strategies to decrease its incidence and both plant extracts and natural products may constitute sources of new chemoprevention agents. Some Brazilian species popularly used to treat inflammatory conditions were selected for evaluation for cancer chemoprevention. A total of 32 extracts/fractions from Hancornia speciosa, Davilla elliptica, Jacaranda caroba, Mansoa hirsuta, Remija ferrugina, Solanum paniculatum and Xyris pterygoblephara, along with a mixture of ursolic and oleanolic acids obtained from J. caroba and a dihydroisocoumarin isolated from aerial parts of X. pterygoblephara were tested for their cancer chemoprevention activity [inhibition of 12‐O‐tetradecanoyl‐13‐acetate (TPA)‐mediated NF‐κB activation, ornithine decarboxylase (ODC) and cyclooxygenase‐1 (COX‐1); induction of antioxidant response element (ARE)]. Several extracts / fractions were active in more than one assay and those from H. speciosa, M. hirsuta and J. caroba mediated strong responses with NF‐κB, COX‐1 and ARE, respectively. Copyright © 2009 John Wiley & Sons, Ltd.     

Reply

Sir, We thank Dr Kazory and Dr Ejaz for their interest in our study[1]. There is     

Skin wound healing,ischemia-reperfusion injury and nerve regeneration: Similarities in the sequential events and molecular basis

Skin wound healing, ischemia-reperfusion injury and nerve regeneration are three important topics for the hand surgeon. The events and molecular basis for each of these three topics are very complex, and previous review articles have discussed each topic separately. The present review demonstrates and comments on the similarities in the sequential events and molecular basis among skin wound healing, ischemia-reperfusion injury and nerve regeneration.