全文获取类型
收费全文 | 1221篇 |
免费 | 50篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 35篇 |
妇产科学 | 15篇 |
基础医学 | 143篇 |
口腔科学 | 66篇 |
临床医学 | 73篇 |
内科学 | 213篇 |
皮肤病学 | 36篇 |
神经病学 | 133篇 |
特种医学 | 41篇 |
外科学 | 210篇 |
综合类 | 4篇 |
一般理论 | 1篇 |
预防医学 | 137篇 |
眼科学 | 14篇 |
药学 | 72篇 |
中国医学 | 5篇 |
肿瘤学 | 71篇 |
出版年
2023年 | 12篇 |
2022年 | 40篇 |
2021年 | 53篇 |
2020年 | 35篇 |
2019年 | 44篇 |
2018年 | 66篇 |
2017年 | 38篇 |
2016年 | 27篇 |
2015年 | 56篇 |
2014年 | 67篇 |
2013年 | 70篇 |
2012年 | 103篇 |
2011年 | 107篇 |
2010年 | 55篇 |
2009年 | 58篇 |
2008年 | 73篇 |
2007年 | 66篇 |
2006年 | 43篇 |
2005年 | 45篇 |
2004年 | 42篇 |
2003年 | 54篇 |
2002年 | 30篇 |
2001年 | 10篇 |
2000年 | 9篇 |
1999年 | 8篇 |
1998年 | 8篇 |
1997年 | 4篇 |
1996年 | 3篇 |
1995年 | 3篇 |
1994年 | 6篇 |
1993年 | 4篇 |
1992年 | 7篇 |
1991年 | 2篇 |
1990年 | 6篇 |
1989年 | 3篇 |
1986年 | 2篇 |
1985年 | 1篇 |
1982年 | 1篇 |
1981年 | 2篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1976年 | 2篇 |
1973年 | 1篇 |
1971年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1966年 | 1篇 |
1965年 | 1篇 |
1963年 | 1篇 |
1959年 | 1篇 |
排序方式: 共有1278条查询结果,搜索用时 15 毫秒
11.
Electrocardiographic prediction of the site of lesion in the anterior descending artery in acute myocardial infarction 总被引:2,自引:0,他引:2
Prieto Solís JA González Fernández C Hernández Hernández MA de la Torre Hernández JM Llorca Díaz J 《Revista espa?ola de cardiología》2002,55(10):1028-1035
INTRODUCTION AND OBJECTIVES: The goal of this study was to analyze the value of electrocardiography in predicting the site of the lesion in the left anterior descending coronary artery, in relation to the first septal and the first diagonal branches, in patients with acute anterior myocardial infarction. METHOD: Ninety consecutive patients who were admitted to the coronary unit with acute anterior myocardial infarction from July 1998 to May 2000 were studied retrospectively. The electrocardiographic changes were analyzed and correlated with the site of the lesion in the anterior descending artery, as determined by coronary angiography. RESULTS: The most useful parameters in predicting the site of the lesion in the left anterior descending coronary artery in acute anterior myocardial infarction are: 1) For lesions proximal to the first septal branch, ST-segment elevation in aVR (p < 0.001) and the absence of Q wave in V4-V6 (p = 0.01). 2) For lesions proximal to the first diagonal branch, abnormal Q wave in aVL (p = 0.01) and ST depression in III (p = 0.05). 3) For lesions proximal to both the first septal and first diagonal branches, ST elevation in aVR (p < 0.001), abnormal Q wave in aVL (p = 0.02), and absence of Q wave in V4-V6 (p = 0.01). 4) For lesions distal to both the first septal and first diagonal branches, abnormal Q wave in V4-V6 (p = 0.001) and absence of ST depression in III (p < 0.001). CONCLUSIONS: In acute anterior myocardial infarction, electrocardiography is useful for predicting the site of the lesion in the left anterior descending coronary artery in relation to the first septal and the first diagonal branches. 相似文献
12.
Fernando J. Rascón-Ramírez Ángela María Carrascosa-Granada Andrés Camilo Vargas-Jiménez Borja Ferrández-Pujante Francisco Ortuño-Andériz 《Neurocirugía (Asturias, Spain)》2021,32(4):194-198
The coronavirus disease 2019 (COVID-19) has amazed by its distinct forms of presentation and severity.COVID-19 patients can develop large-scale ischemic strokes in previously healthy patients without risk factors, especially in patients who develop an acute respiratory distress syndrome (SARS-CoV-2).We hypothesize that ischemic events are usually the result of the combined process of a pro-inflammatory and pro-coagulant state plus vascular endothelial dysfunction probably potentiated by hypoxia, hemodynamic instability, and immobilization, as reported in other cases.To the best of our knowledge, we report the first case of partial obstruction of a vertebral artery in a patient with COVID-19.Decompressive surgery remains a life-saving maneuver in these patients (as in other non-COVID-19 strokes) and requires further investigation. 相似文献
13.
Laura Kropp Anish Baswanth Chakka Svetlana Yatsenko Eleonora Di Gregorio Daniela Lacerenza Giovanna Vaula Flavia Talarico Paola Mandich Camilo Toro Eleonore Eymard Pierre Pierre Labauge Sabina Capellari Pietro Cortelli Filippo Pinto Vairo Diego Miguel Danielle Stubbolo Lourenco Charles Marques William Gahl Odile Boespflug‐Tanguy Atle Melberg Sharon Hassin‐Baer Oren S. Cohen Rastislav Pjontek Armin Grau Thomas Klopstock Brent Fogel Inge Meijer Guy Rouleau Jean‐Pierre L. Bouchard Madhavi Ganapathiraju Adeline Vanderver Niklas Dahl Grace Hobson Alfredo Brusco Quasar Saleem Padiath 《Human mutation》2013,34(8):1160-1171
Autosomal dominant leukodystrophy (ADLD) is an adult onset demyelinating disorder that is caused by duplications of the lamin B1 (LMNB1) gene. However, as only a few cases have been analyzed in detail, the mechanisms underlying LMNB1 duplications are unclear. We report the detailed molecular analysis of the largest collection of ADLD families studied, to date. We have identified the minimal duplicated region necessary for the disease, defined all the duplication junctions at the nucleotide level and identified the first inverted LMNB1 duplication. We have demonstrated that the duplications are not recurrent; patients with identical duplications share the same haplotype, likely inherited from a common founder and that the duplications originated from intrachromosomal events. The duplication junction sequences indicated that nonhomologous end joining or replication‐based mechanisms such fork stalling and template switching or microhomology‐mediated break induced repair are likely to be involved. LMNB1 expression was increased in patients’ fibroblasts both at mRNA and protein levels and the three LMNB1 alleles in ADLD patients show equal expression, suggesting that regulatory regions are maintained within the rearranged segment. These results have allowed us to elucidate duplication mechanisms and provide insights into allele‐specific LMNB1 expression levels. 相似文献
14.
15.
Camilo Corbellini Cristiane Brenner Eilert Trevisan Jorge Hugo Villafa?e Alexandre Doval da Costa Silvia Regina Rios Vieira 《Journal of Physical Therapy Science》2015,27(6):1945-1950
[Purpose] To evaluate pre-extubation variables and check the discriminative validity of
age as well as its correlation with weaning failure in elderly patients. [Subjects and
Methods] Two hundred thirty-nine consecutive patients (48% female) who were on mechanical
ventilation and had undergone orotracheal intubation were divided into four subgroups
according to their age: <59 years, 60–69 years, 70–79 years, and >80 years old. The
expiratory volume (VE), respiratory frequency (f), tidal volume
(VT), and respiratory frequency/tidal volume ratio (f/VT) were used
to examine differences in weaning parameters between the four subgroups, and age was
correlated with weaning failure. [Results] The rate of weaning failure was 27.8% in
patients aged >80 years and 22.1% in patients aged <60 years old. Elderly patients
presented higher f/VT and f values and lower VT values. The areas
under the receiver operating characteristic curves for f/VT ratio were smaller
than those published previously. [Conclusion] Our results indicate that aging influences
weaning criteria without causing an increase in weaning failure.Key words: Weaning, Mechanical ventilation, Aging 相似文献
16.
17.
18.
19.
Lyons JM Karkar A Correa-Gallego CC D'Angelica MI DeMatteo RP Fong Y Kingham TP Jarnagin WR Brennan MF Allen PJ 《HPB : the official journal of the International Hepato Pancreato Biliary Association》2012,14(7):469-475