全文获取类型
收费全文 | 66352篇 |
免费 | 5660篇 |
国内免费 | 3436篇 |
专业分类
耳鼻咽喉 | 746篇 |
儿科学 | 646篇 |
妇产科学 | 810篇 |
基础医学 | 8933篇 |
口腔科学 | 1234篇 |
临床医学 | 7683篇 |
内科学 | 10924篇 |
皮肤病学 | 1121篇 |
神经病学 | 3912篇 |
特种医学 | 3400篇 |
外国民族医学 | 37篇 |
外科学 | 7534篇 |
综合类 | 7789篇 |
现状与发展 | 7篇 |
一般理论 | 4篇 |
预防医学 | 3754篇 |
眼科学 | 1913篇 |
药学 | 6525篇 |
43篇 | |
中国医学 | 2809篇 |
肿瘤学 | 5624篇 |
出版年
2024年 | 147篇 |
2023年 | 852篇 |
2022年 | 2405篇 |
2021年 | 3263篇 |
2020年 | 2107篇 |
2019年 | 2096篇 |
2018年 | 2322篇 |
2017年 | 1942篇 |
2016年 | 2265篇 |
2015年 | 3215篇 |
2014年 | 3914篇 |
2013年 | 3719篇 |
2012年 | 5715篇 |
2011年 | 5756篇 |
2010年 | 3670篇 |
2009年 | 3022篇 |
2008年 | 3877篇 |
2007年 | 3739篇 |
2006年 | 3333篇 |
2005年 | 3107篇 |
2004年 | 2304篇 |
2003年 | 2047篇 |
2002年 | 1787篇 |
2001年 | 1294篇 |
2000年 | 1306篇 |
1999年 | 1226篇 |
1998年 | 692篇 |
1997年 | 716篇 |
1996年 | 561篇 |
1995年 | 469篇 |
1994年 | 386篇 |
1993年 | 272篇 |
1992年 | 353篇 |
1991年 | 266篇 |
1990年 | 233篇 |
1989年 | 213篇 |
1988年 | 162篇 |
1987年 | 151篇 |
1986年 | 116篇 |
1985年 | 106篇 |
1984年 | 57篇 |
1983年 | 55篇 |
1982年 | 24篇 |
1981年 | 29篇 |
1980年 | 17篇 |
1979年 | 31篇 |
1978年 | 14篇 |
1973年 | 13篇 |
1971年 | 10篇 |
1969年 | 10篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
71.
72.
Eun Young Jung Hyung Joo Suh Wan Soo Hong Dong Geon Kim Yang Hee Hong In Sun Hong Un Jae Chang 《Nutrition Research》2009,29(7):457-461
Cooking processes that gelatinize granules or disrupt structure might increase the glucose and insulin responses because a disruption of the structure of starch by gelatinization increases its availability for digestion and absorption in the small intestine. We hypothesized that the uncooked form of rice, which has a relatively low degree of gelatinization even though in powder form, would result in lower metabolic glucose and insulin responses compared with cooked rice (CR). To assess the effects of the gelatinization of rice on metabolic response of glucose and insulin, we investigated the glucose and insulin responses to 3 rice meals of different gelatinization degree in female college students (n = 12): CR (76.9% gelatinized), uncooked rice powder (UP; 3.5% gelatinized), and uncooked freeze-dried rice powder (UFP; 5.4% gelatinized). Uncooked rice powders (UP and UFP) induced lower glucose and insulin responses compared with CR. The relatively low gelatinization degree of UPs resulted in low metabolic responses in terms of the glycemic index (CR: 72.4% vs UP: 49.7%, UFP: 59.8%) and insulin index (CR: 94.8% vs UP: 74.4%, UFP: 68.0%). In summary, UPs that were less gelatinized than CR induced low postprandial glucose and insulin responses. 相似文献
73.
扩髓交锁髓内钉治疗股骨、胫骨干骨折 总被引:7,自引:2,他引:5
目的探讨交锁髓内钉治疗股骨、胫骨干骨折的临床效果.方法应用交锁髓内钉治疗不同类型的股骨干骨折18例,胫骨干骨折15例.结果33例患者随访8~24个月,平均15.2个月,33例均骨性愈合.未出观畸性愈合、再骨折、断钉及膝、踝关节僵硬等并发症.结论交锁髓内钉治疗股骨、胫骨干骨折治愈率高,并发症少,效果满意. 相似文献
74.
75.
76.
77.
305例尿石成份分析及预防对策 总被引:13,自引:3,他引:10
目的研究一种快速、简便的方法对泌尿系结石进行分析,并探讨其防治方法。方法用化学常量法对305例患者的尿石标本进行化学成份测定,并结合临床资料进行分析。结果发现结石发病男性多于女性(比例为3.2∶1),20~50岁多发,上尿路结石多于下尿路结石(5.4∶1)。结石中草酸钙检出率达82%,尿酸盐55.2%,磷酸钙48.6%,磷酸镁铵与碳酸磷灰石则多见于泌尿系感染病例,胱氨酸结石少见。结论化学常量法分析泌尿系结石简便、快捷、准确。结石成份分析对于了解结石成因、预防结石复发具有一定的意义。 相似文献
78.
Zusammenfassung GRUNDLAGEN: Das Ziel dieser Untersuchung war, die Machbarkeit und Wirksamkeit der Fokus-Sanierung via Mini-Thorakotomie zur Therapie einer kavernösen Lungentuberkulose zu prüfen. METHODIK: Der Mini-Thorakotomie-Zugang wurde in 18 Patienten angewendet (Alter, 25–75 Jahre; median, 47,5 Jahre). Die Patienten hatten eine kavernöse Lungentuberkulose oder ein Lungentuberkulom nach tuberkulostatischer Therapie oder waren Patienten, die auf diese Therapie nicht angesprochen haben. 8 Patienten mit chronischer kavernöser Lungentuberkulose und 10 Patienten mit Tuberkulom haben sich der Fokus-Sanierung, Spülung und Faltnaht unterzogen. ERGEBNISSE: Es gab keine operative Mortalität. Alle Patienten waren klinisch saniert, hatten keinen Nachweis für Bakterien im Sputum, im Röntgen hatten die Lungenschatten abgenommen. Die Dauer der Operation betrug 30–120 min (median, 75 min), der intraoperative Blutverlust war 100–200 ml (median, 153 ml). Der postoperative Spitalsaufenthalt betrug 21–42 Tage (median, 30 Tage). Das Follow-up nach 1–4 Jahren (median, 2,5 Jahre) zeigte keine Komplikation und kein Rezidiv der Grunderkrankung. SCHLUSSFOLGERUNGEN: MTFC ist eine sichere und technisch machbare Methode zur Therapie der Lungentuberkulose oder des Tuberkuloms bei Schonung der Lungenfunktion. 相似文献
79.
Tae-Jin Song M.D. Ph.D. David P. Eisenberg M.D. Prasad S. Adusumilli M.D. Michael Hezel B.S. Yuman Fong M.D. 《Journal of gastrointestinal surgery》2006,10(4):532-542
The rising incidence of hepatocellular carcinoma (HCC) in western countries, along with the poor prognosis offered by present-day
treatment modalities, makes novel therapies for this disease necessary. Oncolytic herpes simplex viruses (HSV) are replication-competent
viruses that are highly effective in the treatment of a wide variety of experimental models of human malignancies. This study
seeks to investigate the effectiveness of oncolytic herpes viruses in the treatment of primary HCC cell lines. Sixteen commercially
available human HCC cell lines were studied. G207 is an attenuated, replication-competent, oncolytic HSV engineered to selectively
replicate within cancer cells. Cell lines were tested for viral sensitivity to G207 and their ability to support viral replication
using standard cytotoxicity and viral replication assays. Eleven of 16 cell lines were moderately to highly sensitive to G207
viral oncolysis. HCC cell lines additionally demonstrated the ability to support viral replication in vitro with as high as
800-fold amplification of the administered viral dose observed. G207 is cytotoxic to, and efficiently replicates within, HCC
cell lines in vitro. From these data, we suggest that oncolytic HSV therapy may have a role in the treatment of HCC, and in
vivo studies are warranted.
Presented in part at the 2005 American Hepato-Pancreato-Biliary Association Congress, Hollywood, Florida, April 14–17, 2005.
Supported by grants R01CA75461 and R01CA72632 from the National Institutes of Health, and by grant MBC-99366 from the American
Cancer Society (Yuman Fong). 相似文献
80.
BACKGROUND. A health risk appraisal (HRA) is a tool for health promotion. Conversational microcomputer-based HRAs may be more cost effective than other HRA formats. The acceptability of conversational HRAs, however, has not been demonstrated for older adults. METHODS. We studied the acceptability of a conversational microcomputer-based HRA in a sample of 247 adults at the Minnesota State Fair and the Senior Options Exposition. All users were offered the appraisal via mouse or keyboard interface. Acceptability was measured in terms of user-reported helpfulness, intent to change, time of use, and willingness to view HRA health recommendations. Data on completion time and willingness to view HRA recommendations were collected for Senior Exposition users only. Regression analyses were used to examine the combined impact of interface (mouse or keyboard), location (State Fair or Senior Exposition), age, and sex on user acceptability. Results. Interface and location had no effect on helpfulness or change ratings. Older users rated the appraisal more helpful (P less than .007). Both older and female users reported more intent to change behavior (P = .016, both). Time to use the appraisal was related to interface, age, and sex. Mouse users (P less than .0001), older users (P less than .0001) and female users (P less than .05) took significantly longer to use the appraisal. Significantly more mouse users declined to see recommendations (P less than .02). CONCLUSIONS. Older users can derive as much or more value from conversational health risk appraisals as younger users; however, a mouse interface may be less effective for this age group. 相似文献