全文获取类型
收费全文 | 3625篇 |
免费 | 376篇 |
国内免费 | 41篇 |
专业分类
耳鼻咽喉 | 26篇 |
儿科学 | 140篇 |
妇产科学 | 67篇 |
基础医学 | 337篇 |
口腔科学 | 10篇 |
临床医学 | 481篇 |
内科学 | 1358篇 |
皮肤病学 | 75篇 |
神经病学 | 320篇 |
特种医学 | 49篇 |
外科学 | 332篇 |
综合类 | 141篇 |
预防医学 | 303篇 |
眼科学 | 37篇 |
药学 | 187篇 |
1篇 | |
中国医学 | 10篇 |
肿瘤学 | 168篇 |
出版年
2024年 | 12篇 |
2023年 | 74篇 |
2022年 | 28篇 |
2021年 | 74篇 |
2020年 | 76篇 |
2019年 | 35篇 |
2018年 | 138篇 |
2017年 | 132篇 |
2016年 | 121篇 |
2015年 | 111篇 |
2014年 | 110篇 |
2013年 | 138篇 |
2012年 | 288篇 |
2011年 | 371篇 |
2010年 | 100篇 |
2009年 | 122篇 |
2008年 | 263篇 |
2007年 | 261篇 |
2006年 | 196篇 |
2005年 | 228篇 |
2004年 | 300篇 |
2003年 | 224篇 |
2002年 | 196篇 |
2001年 | 94篇 |
2000年 | 55篇 |
1999年 | 37篇 |
1998年 | 45篇 |
1997年 | 18篇 |
1996年 | 11篇 |
1995年 | 17篇 |
1994年 | 19篇 |
1993年 | 6篇 |
1992年 | 15篇 |
1991年 | 6篇 |
1990年 | 14篇 |
1989年 | 8篇 |
1988年 | 7篇 |
1987年 | 7篇 |
1986年 | 21篇 |
1985年 | 10篇 |
1984年 | 7篇 |
1983年 | 3篇 |
1981年 | 3篇 |
1979年 | 8篇 |
1977年 | 5篇 |
1970年 | 2篇 |
1968年 | 2篇 |
1966年 | 3篇 |
1965年 | 2篇 |
1946年 | 2篇 |
排序方式: 共有4042条查询结果,搜索用时 15 毫秒
121.
122.
123.
Ingrid B. de Groot J. Iraida E. Veen Paul J. M. van der Boog Sandra van Dijk Anne M. Stiggelbout Perla J. Marang‐van de Mheen The PARTNER‐study group 《Clinical transplantation》2013,27(4):E415-E423
Purpose of this study was to assess whether living (LD) and deceased donor (DD) kidney transplant recipients differ in health‐related quality of life (HRQoL), fatigue and societal participation, depending on time since transplantation and after adjustment for clinical and demographic variables. A questionnaire study was performed among 309 LD and 226 DD recipients (response rate 74% and 61%) transplanted between 1997 and 2009. After adjustment for age, sex, and education, LD recipients transplanted less than or equal to five yr ago experienced better HRQoL than DD recipients on the domains' role limitations due to physical problems, general health perception, and on the physical component summary score (all p < 0.05) and a better societal participation (all subscales, p < 0.05). No differences were found in the mental health domains. The LD recipients also had better renal clearance than DD recipients (62.1 vs. 55.9 mL/min, p = 0.01). After additional adjustment for renal clearance, the differences in HRQoL and societal participation between LD and DD recipients remained. No differences were found in recipients transplanted more than five yr ago. We conclude that LD recipients on average have better HRQoL and societal participation than DD recipients, in the first years after transplantation. 相似文献
124.
125.
126.
Marisa Iborra Belén Beltrán Agnes Fernández-Clotet Eva Iglesias-Flores Pablo Navarro Montserrat Rivero Ana Gutiérrez Mónica Sierra-Ausin Francisco Mesonero Rocío Ferreiro-Iglesias Joaquín Hinojosa Xavier Calvet Beatriz Sicilia Carlos González-Muñoza Beatriz Antolín María González-Vivo Ana Y. Carbajo Santiago García-López Albert Martín-Cardona Gerard Surís María Dolores Martin-Arranz Ruth de Francisco Fiorella Cañete Eugeni Domènech Pilar Nos GETECCU group 《Alimentary pharmacology & therapeutics》2020,52(6):1017-1030
127.
Daniel?Junker Thomas?R.?W.?Herrmann Markus?Bader Jasmin?Bektic Gregor?Henkel Stephan?Kruck Markus?Sandbichler David?Schilling Georg?Sch?fer Udo?Nagele the Training Research in Urological Surgery Therapy group 《World journal of urology》2016,34(2):245-252
Introduction
Experience from interdisciplinary cooperation revealed the need for a prostate mapping scheme to communicate multiparametric MRI (mpMRI) findings between radiologists, urologists, and pathologists, which should be detailed, yet easy to memorize. For this purpose, the ‘Prostate interdisciplinary communication and mapping algorithm for biopsy and pathology’ (PIC-MABP) was developed. This study evaluated the accuracy of the PIC-MABP system.Methods
PIC-MABP was tested and validated in findings of 10 randomly selected patients from routine clinical practise with 18 histologically proven cancer lesions. Patients received an mpMRI of the prostate prior to prostatectomy. After surgery the prostates were prepared as whole-mount step sections. Cancer lesions, which were found suspicious on mpMRI, were assigned to the according PIC-MABP sectors by a radiologist. MpMRI slides were masked and sent to seven urologists from different centres, providing only the PIC-MABP location of each lesion. Urologists marked the accordant regions. Then mpMRI slides were unmasked, and the correctness of each mark was evaluated.Results
One hundred and seventeen of the 126 marks (93 %) were correctly assigned. Detection rates differed for lesions >0.5 cc compared with lesions <0.5 cc (p < 0.005): 3/7 (43 %) marks were correctly assigned in lesions <0.3 cc, 16/21 (76 %) in lesions with 0.3–0.5 cc, and 98/98 (100 %) in lesions >0.5 cc. Interobserver agreement was good for lesions >0.5 cc and poor for lesions <0.3 cc (Fleiss Kappa 1 vs. 0.0175).Conclusion
PIC-MABP seems to be a reliable system to communicate the location of mpMRI findings >0.5 cc between different disciplines and can be a useful guidance for cognitive mpMRI/TRUS fusion biopsy.128.
Site‐Dependent Reference Point Microindentation Complements Clinical Measures for Improved Fracture Risk Assessment at the Human Femoral Neck 下载免费PDF全文
Stefania D'Angelo Douglas G Dunlop Richard OC Oreffo Cyrus Cooper and the Observational Study Examining Osteoporosis group 《Journal of bone and mineral research》2016,31(1):196-203
In contrast to traditional approaches to fracture risk assessment using clinical risk factors and bone mineral density (BMD), a new technique, reference point microindentation (RPI), permits direct assessment of bone quality; in vivo tibial RPI measurements appear to discriminate patients with a fragility fracture from controls. However, it is unclear how this relates to the site of the most clinically devastating fracture, the femoral neck, and whether RPI provides information complementary to that from existing assessments. Femoral neck samples were collected at surgery after low‐trauma hip fracture (n = 46; 17 male; aged 83 [interquartile range 77–87] years) and compared, using RPI (Biodent Hfc), with 16 cadaveric control samples, free from bone disease (7 male; aged 65 [IQR 61–74] years). A subset of fracture patients returned for dual‐energy X‐ray absorptiometry (DXA) assessment (Hologic Discovery) and, for the controls, a micro‐computed tomography setup (HMX, Nikon) was used to replicate DXA scans. The indentation depth was greater in femoral neck samples from osteoporotic fracture patients than controls (p < 0.001), which persisted with adjustment for age, sex, body mass index (BMI), and height (p < 0.001) but was site‐dependent, being less pronounced in the inferomedial region. RPI demonstrated good discrimination between fracture and controls using receiver‐operating characteristic (ROC) analyses (area under the curve [AUC] = 0.79 to 0.89), and a model combining RPI to clinical risk factors or BMD performed better than the individual components (AUC = 0.88 to 0.99). In conclusion, RPI at the femoral neck discriminated fracture cases from controls independent of BMD and traditional risk factors but dependent on location. The clinical RPI device may, therefore, supplement risk assessment and requires testing in prospective cohorts and comparison between the clinically accessible tibia and the femoral neck. © 2015 American Society for Bone and Mineral Research. 相似文献
129.
130.
Jaime Ruiz-Tovar Lorea Zubiaga Maria Diez Ana Murcia Evangelina Boix José Luis Muñoz Carolina Llavero OBELCHE group 《Obesity surgery》2016,26(6):1221-1227