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Jian-ya Zhou Fa-di Tang Guo-gen Mao Jie Shao Yan Wang Ru-lian Bian 《浙江大学学报(医学版)》2003,32(4):315-8, 326
OBJECTIVE: To study the effect of eucalyptus globulus oil on the activity of nuclear factor-kappaB(NF-kappaB) in THP-1 cell line. METHODS: THP-1 cells were cultured with or without eucalyptus globulus oil at different concentrations (1, 10, 100 mg x L(-1), 30 min) before being stimulated with lipopolysaccharide (LPS, 1 mg x L(-1), 30 min). The location of NF-kappaB p65 subunit (NF-kappaB/p65) in THP-1 cells was detected by indirect immunofluorescence and laser scanning confocal microscope. The expression of NF-kappaB/p65 in nuclei was measured by Western-blot analysis. RESULT: The FITC-label NF-kappaB/p65 was mainly located in the nuclei after THP-1 cells were stimulated with LPS. Whereas, no fluorescence were seen in the nuclei of cells pretreated with eucalyptus globulus oil. This effect on NF-kappaB/p65 nuclear translocation was in a concentration dependent manner. CONCLUSION: Eucalyptus globulus oil inhibits the nuclear translocation of NF-kappaB induced by LPS in THP-1 cells. 相似文献
13.
(1)目的 总结探讨11例非体外循环冠状动脉搭桥术(OPCAB)的经验。(2)方法 2001年6-12月对11例冠心患采用非体外循环心脏不停跳方法完成冠状动脉搭桥术。(3)结果 共搭桥35支,平均3.17支/例,其中左乳内动脉桥8支,大隐静脉桥27支。6例患(54.5%)未血,无手术死亡及并发症。(4)结论 非体外循环搭桥术克服了体外循环搭桥术(CABG)的诸多缺点和弊端,手术简化,时间缩短,适应证扩大,并发症明显减少,效果满意。 相似文献
14.
Intestinal obstruction proximal to a transition zone without an interposed physical barrier usually indicates Hirschsprung disease. The authors report one case of focal small bowel muscular thinning just distal to a transition zone that produced clinical and radiographic findings that simulated long-segment Hirschsprung disease in a 2-day-old infant. 相似文献
15.
通过实验室和口腔科临床观察表明:TD清洗消毒剂(氯化磷酸三钠)对金黄色葡萄球菌、绿脓杆菌和枯草杆菌黑色变种的平均杀菌率为100.0%,对口腔科器械消毒无菌率为100%,对被HBsAg阳性血清污染的器械浸泡30分钟转阴率为98.1%。其消毒效果优于新洁尔灭,与戊二醛相同。在口腔科使用两年,未见金属器械有锈斑生成。 相似文献
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Application of reflectance spectroscopy to the estimation of uric acid, urea and glucose: an evaluation of the Ames Seralyzer 下载免费PDF全文
An original approach to the measurement of analytes in clinical chemistry has now become available, in which dry reagent strip technology is linked to measurement by reflectance spectroscopy. The present studies have evaluated the performance of the first of these test systems—for uric acid, urea and glucose, in serum—by comparison with conventional liquid chemistry methods. Satisfactory performance in terms of both precision and accuracy was obtained for all three test systems, the current “state-of-the-art” performance criteria being met; the Seralyzer system proved reliable and easy to use in the hands of trained operators. It should find a place as a “Stat” analyser in the laboratory, in specified wards and in Health Centres. 相似文献
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Influence of co-culture with established human endometrial epithelial and stromal cell lines on sperm movement characteristics 总被引:2,自引:0,他引:2
The effects of co-culture of human spermatozoa with human immortalized
endometrial cells - epithelial or stromal - on sperm movement
characteristics, including hyperactivation, were studied using computer-
assisted sperm analysis (CASA). Epithelial and stromal cell types could be
separated following 8-10 days of culture of endometrial cells originating
from human biopsies. Both cell types were immortalized by the SV 40 large T
antigen. Co-incubation of sperm with epithelial and stromal monolayers
enhanced the rate of hyperactivation: 24.9% (P <0.05) and 17.8% (P =
0.05) versus 9.5% as control, respectively, whereas the majority of
motility parameters remained unchanged. Conditioned media had no effect
upon sperm parameters, including hyperactivation. Co-incubation with either
monolayer was able to maintain sperm motility over a longer period than
incubation in control medium alone. In four patients whose spermatozoa did
not exhibit hyperactivation, co-incubation with epithelial cells, but not
conditioned medium, allowed normal rates of hyperactivation (range: 6.9-
15.6%).
相似文献
20.
Synchronous ileal and colonic adenocarcinomas associated with Crohn's disease: report of a case with a focus on genetic alterations and carcinogenesis 下载免费PDF全文
Baisse B Fontolliet C Bian YS Vuilleumier H Benhattar J 《Journal of clinical pathology》2004,57(8):885-887
Patients with Crohn's disease have an increased risk of developing intestinal tumours. However, the carcinogenic mechanisms remain poorly understood. To address this question, this report describes an unusual case of Crohn's disease complicated by synchronous small intestinal and colonic adenocarcinomas. Genetic events in both the tumours and their adjacent mucosae were evaluated and the tumorigenesis of these cancers is discussed. 相似文献