全文获取类型
收费全文 | 1273篇 |
免费 | 49篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 33篇 |
儿科学 | 46篇 |
妇产科学 | 55篇 |
基础医学 | 99篇 |
口腔科学 | 86篇 |
临床医学 | 77篇 |
内科学 | 215篇 |
皮肤病学 | 11篇 |
神经病学 | 132篇 |
特种医学 | 104篇 |
外科学 | 308篇 |
综合类 | 17篇 |
一般理论 | 1篇 |
预防医学 | 31篇 |
眼科学 | 28篇 |
药学 | 60篇 |
肿瘤学 | 25篇 |
出版年
2023年 | 10篇 |
2022年 | 19篇 |
2021年 | 27篇 |
2020年 | 13篇 |
2019年 | 27篇 |
2018年 | 31篇 |
2017年 | 32篇 |
2016年 | 44篇 |
2015年 | 37篇 |
2014年 | 66篇 |
2013年 | 83篇 |
2012年 | 84篇 |
2011年 | 87篇 |
2010年 | 50篇 |
2009年 | 43篇 |
2008年 | 77篇 |
2007年 | 102篇 |
2006年 | 94篇 |
2005年 | 98篇 |
2004年 | 87篇 |
2003年 | 82篇 |
2002年 | 60篇 |
2001年 | 15篇 |
2000年 | 9篇 |
1999年 | 4篇 |
1998年 | 7篇 |
1997年 | 2篇 |
1996年 | 10篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 1篇 |
1992年 | 8篇 |
1991年 | 1篇 |
1990年 | 2篇 |
1988年 | 1篇 |
1980年 | 1篇 |
1979年 | 1篇 |
1978年 | 2篇 |
1977年 | 1篇 |
1976年 | 2篇 |
1974年 | 2篇 |
1965年 | 1篇 |
排序方式: 共有1328条查询结果,搜索用时 15 毫秒
51.
Erhan Arslan Irsadi Demirci Mehmet Oguz Kılıncaslan Cigdem Hacıfazlıoglu Tugcan Demir Ismail Demirkale 《European spine journal》2014,23(5):1044-1051
Purpose
The aim of this study was to demonstrate regeneration of intervertebral discs undergoing laser therapy with sagittal relaxation time (T2) mapping after a long-term follow-up.Materials and methods
Fourteen patients (9 men, 5 women; age range 20–57 years; mean age 36.5 years) treated with percutaneous 908-nm wave-length diode laser nucleoplasty for lumbar disc prolapsus at our clinic between January 2006 and June 2009 were studied. For the application of laser nucleoplasty in the past, patients who did not have central canal stenosis and/or lateral stenosis, sequestered disc fragment, operation scars and bleeding disorders were selected. The intervertebral disc levels undergoing laser therapy were L3–L4 (n = 2) or L4–L5 (n = 12). Patients were called for follow-up visits after a maximum 6-years (n = 2) or a minimum 3 years (n = 3) with a mean of 4.4 years. The patients’ clinical status for leg pain was evaluated according to the visual analog scale (VAS) and subsequently, a lumbar magnetic resonance imaging was performed. Sagittal T2 mapping was performed for the intervertebral discs undergoing laser nucleoplasty. We analyzed the relationship between T2 in the regions of interest (ROIs), which is known to correlate with changes in the composition of intervertebral discs, and the degree of degeneration determined using the Pfirrmann grading system and VAS of patients.Results
On the basis of the evaluation of the results of intervertebral discs in all patients, there was a significant increase in T2 in the anterior NP (ROI 2, +10.3 ms; p < 0.05). A significant increase was noted in T2 in the middle NP (ROI 3, +24.6 ms; p < 0.001). The most significant increase was recorded for the posterior NP (ROI 4, +28.6 ms; p < 0.001). No significant decrease was found in T2 in the anterior and posterior AF (ROI 1, ?1.5 ms; p = 0.925; ROI 5, ?0.1 ms; p = 0.683). According to the Pfirrmann grading system, disc degeneration grades before laser therapy were recorded as grade III (n = 6) and grade IV (n = 8) whereas disc degeneration grades after laser therapy were found to be grade I (n = 6) and II (n = 8). A significant decrease was noted in Pfirrmann grades of disc degeneration after laser therapy (p < 0.0005).Conclusions
In this study, there was a prolongation of T2 indicating regeneration in the nucleus pulposus after laser therapy and these results were found to be consistent with VAS measurements after a long-term follow-up. This study, which demonstrates the quantitative efficacy of laser therapy, indicates that MRG can be more effectively used in the future. 相似文献52.
Yasemin Top?u Erhan Bayram Pakize Karao?lu Ulu? Yi? Semra H?z Kurul 《Annals of Indian Academy of Neurology》2014,17(4):437-440
Metabolic myopathies due to disorders of lipid metabolism are a heterogeneous group of diseases. Newborns may present with hypotonia and convulsions, while progressive proximal muscle weakness or recurrent episodes of muscle weakness accompanied by rhabdomyolysis/myoglobinuria may be seen in older ages. There is little knowledge on detection of disorders of lipid metabolism by acylcarnitine profile (ACP) analysis by tandem mass spectrometry outside the neonatal period particularly in cases with recurrent rhabdomyolysis first presenting in adolescence and adulthood. Two adolescent female cases presented with episodes of rhabdomyolysis and muscle weakness. A 13-year-old patient had five episodes of rhabdomyolysis triggered by infections. Tandem mass spectrometry was normal. A 16-year-old female patient was hospitalized eight times due to recurrent rhabdomyolysis. Increased levels of C14:2, C14:1, and C14 were determined in tandem mass spectrometry. Final diagnoses were carnitine palmitoyltransferase II (CPT II) deficiency and very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency. Increased serum levels of long-chain acylcarnitine can guide to the diagnosis of lipid metabolism disorders. Serum ACP should be performed before enzyme assay and genetic studies. 相似文献
53.
Seluk Kanat Hakan akr Ahmet Tütüncü Erhan Tenekecioglu 《Pacing and clinical electrophysiology : PACE》2019,42(3):309-312
We herein report successful cryoablation of paroxysmal atrial fibrillation via right jugular vein in a patient with interrupted inferior vena cava. We preferred cryoablation instead of radiofrequency ablation in the treatment of our patient. For stronger support in aiming the Brockenbrough needle toward the septum, we manuallly curved the needle with a 120° angle about 6 cm proximal to the tip. After successful transseptal puncture, we performed balloon dilatation in the septal puncture zone to facilitate passage. Cryoablation has theoretical advantage, particularly in challenging anatomies, in which it eliminates the need for point‐by‐point ablation around the pulmonary vein. 相似文献
54.
Muhammet Gürdo?an Hasan Ari Erhan Tenekecio?lu Selma Ar? Tahsin Bozat Vedat Koca Mehmet Melek 《Arquivos brasileiros de cardiologia》2016,106(2):84-91
Background
Atrial fibrillation (AF) is the most common arrhythmia in adults, and is encountered in 10-15% of the patients with hyperthyroidism. Unless euthyroidism is restored, pharmacological or electrical cardioversion is controversial in patients with AF who remain hyperthyroid.Objective
The aim of this study was to assess the efficacy of electrical cardioversion and predictors of AF recurrence in hyperthyroid and euthyroid patients.Methods
The study included 33 hyperthyroid (21 males) and 48 euthyroid (17 males) patients with persistent AF. The patients were sedated with intravenous midazolam before undergoing electrical cardioversion delivered by synchronized biphasic shocks. Rates of AF recurrence were recorded.Results
Mean follow-up was 23.63 ± 3.74 months in the hyperthyroid group and 22.78 ± 3.15 months in the euthyroid group (p = 0.51). AF recurred in 14 (43.8%) and 21 (44.7%) patients in each group, respectively (p = 0.93). Multivariate regression analysis in each group showed that AF duration was the only predictor of AF recurrence, with odds ratios of 1.38 (95% confidence interval [CI] = 1.05 - 1.82, p = 0.02) in the hyperthyroid group and 1.42 (95% CI = 1.05 - 1.91, p= 0.02) in the euthyroid group.Conclusion
Rates of long-term AF recurrence were similar in successfully cardioverted hyperthyroid and euthyroid patients. The only predictor of AF recurrence in both groups was AF duration. 相似文献55.
Background and objectives
Laryngoscopy and intubation can cause hemodynamic response. Various medications may be employed to control that response. In this study, we aimed to compare the effects of dexmedetomidine, fentanyl and esmolol on hemodynamic response.Method
Ninety elective surgery patients who needed endotracheal intubation who were in American Society of Anesthesiology I–II group and ages between 21 and 65 years were included in that prospective, randomized, double‐blind study. Systolic, diastolic, mean arterial pressures, heart rates at the time of admittance at operation room were recorded as basal measurements. The patients were randomized into three groups: Group I (n = 30) received 1 μg/kg dexmedetomidine with infusion in 10 min, Group II (n = 30) received 2 μg/kg fentanyl, Group III received 2 mg/kg esmolol 2 min before induction. The patients were intubated in 3 min. Systolic, diastolic, mean arterial pressures and heart rates were measured before induction, before intubation and 1, 3, 5, 10 min after intubation.Results
When basal levels were compared with the measurements of the groups, it was found that 5 and 10 min after intubation heart rate in Group I and systolic, diastolic, mean arterial pressures in Group III were lower than other measurements (p < 0.05).Conclusions
Dexmedetomidine was superior in the prevention of tachycardia. Esmolol prevented sytolic, diastolic, mean arterial pressure increases following intubation. We concluded that further studies are needed in order to find a strategy that prevents the increase in systemic blood pressure and heart rate both. 相似文献56.
57.
58.
Erhan Akinci Max-Oskar Wieser Simon Vanscheidt Shirin Diop Vera Flasbeck Burhan Akinci Cora Stiller Georg Juckel Paraskevi Mavrogiorgou 《Psychiatry investigation》2022,19(3):178
ObjectiveDespite the numerous findings on the altered emotion recognition and dysfunctional social interaction behavior of depressive patients, a lot of the relationships are not clearly clarified.MethodsIn this pilot study, 20 depressive patients (mean±SD, 38.4±14.2) and 20 healthy subjects (mean±SD, 38.9±15.3) (each in dyads) were videographed. We then analyzed their social interaction behavior and emotion processing in terms of emotion recognition, their own emotional experience, and the expression of emotions under the conditions of a semi-structured experimental paradigm. ResultsPatients showed more significant impairment regarding the dimensions of social interaction behavior (i.e., attention, interest, and activity) and their interaction behavior was characterized by neutral affectivity, silence, and avoidance of direct eye contact. This interactive behavioral style was statistically related to depressive psychopathology. There were no differences concerning emotion recognition. ConclusionImpairments of non-verbal and verbal social interaction behavior of depressive patients seem to be less associated with disturbances of basic skills of emotion recognition. 相似文献
59.
Paketci Cem Edem Pinar Okumus Canan Sarioglu Fatma Ceren Bayram Erhan Hiz Semra Yis Uluç 《Journal of neurovirology》2020,26(2):270-272
Journal of NeuroVirology - Acute cerebellitis is one of the most common cerebellar disorders and occurs due to para-infectious, post-infectious, or post-vaccination cerebellar inflammation. Herpes... 相似文献
60.
Evaluation of Different Thickness,Die Color,and Resin Cement Shade for Veneers of Multilayered CAD/CAM Blocks
下载免费PDF全文
![点击此处可从《Journal of prosthodontics》网站下载免费的PDF全文](/ch/ext_images/free.gif)